Devices, systems and methods for tissue resection

Patent metadata

Field	Value
Publication number	US-11389185-B2
Application number	US-201916419918-A
Country	US
Kind code	B2
Filing date	May 22, 2019
Priority date	May 23, 2018
Publication date	Jul 19, 2022
Grant date	Jul 19, 2022

Abstract

Exemplary embodiments of the present disclosure relate to devices, systems, and methods for tissue resection in a body lumen of a patient, and may include an elongate body having a cavity at a distal end and a tissue retractor extendable distally from the distal end of the elongate body. The tissue retractor may include an expansion mechanism. The expansion mechanism may include a plurality of arms each having a first end coupled around a distal cap and expandable radially outward from the distal cap such that an anchoring mechanism on a second end of the arms is engageable with selected tissue for resection of the body lumen. The tissue resection device may further include a tissue resecting device.

First claim

What is claimed is:

1. A device for tissue resection from within a body lumen, comprising:
an elongate body having a cavity at a distal end;
a tissue retractor extendable distally from the distal end of the elongate body and including an expansion mechanism, the expansion mechanism including a plurality of arms each having a first end coupled around a distal cap and expandable radially outward from the distal cap such that an anchoring mechanism on a tip of a second end of each arm of the plurality of arms is engageable with selected tissue for resection of the body lumen;
a tissue resecting device; and
a tissue closure device disposed on an outer surface of the distal end of the elongate body, the tissue closure device configured to be deliverable off of the elongate body.

2. The tissue resection device according to claim 1 , further comprising a sheath attached to the tissue retractor and extendable from the elongate body.

3. The tissue resection device according to claim 2 , wherein the expansion mechanism further includes a plurality of connectors each having a first end coupled to the sheath and a second end coupled to a respective arm.

4. The tissue resection device according to claim 2 , wherein the expansion mechanism is configured to radially expand symmetrically around the distal cap and the sheath.

5. The tissue resection device according to claim 2 , wherein the expansion mechanism is configured to radially expand asymmetrically around the distal cap and the sheath.

6. The tissue resection device according to claim 1 , wherein the tissue retractor is configured to extend through a wall of the body lumen, the plurality of arms positioned substantially parallel to the elongate body, and engage the selected tissue for resection when the plurality of arms is expanded radially.

7. The tissue resection device according to claim 1 , wherein the tissue resecting device is an internal shear edge of the cavity, a shear proximal edge of the distal cap, or a shear edge of the distal end of the elongate body, or combinations thereof.

8. The tissue resection device according to claim 1 , wherein the tissue resecting device is a mechanical cutting tool or a cauterizing tool, or combinations thereof.

9. The tissue resection device according to claim 1 , wherein each arm of the plurality of arms is independently articulatable.

10. The tissue resection device according to claim 1 , wherein the tissue closure device is deliverable within the body lumen.

11. A system for tissue resection from within a body lumen, comprising:
a lumen extendable into a patient, the lumen including one or more working channels for delivering accessories to selected tissue for resection of the body lumen; and
a tissue resection device deliverable over the lumen, the tissue resection device including:
an elongate body having a cavity at a distal end;
a tissue retractor extendable distally from the distal end of the elongate body and including an expansion mechanism, the expansion mechanism including a plurality of arms each having a first end coupled circumferentially around a distal cap and expandable radially outward from the distal cap such that an anchoring mechanism on a tip of a second end of each arm of the plurality of arms is engageable with the selected tissue for resection of the body lumen;
a tissue resecting device; and
a tissue closure device disposed on an outer surface of the distal end of the elongate body, the tissue closure device configured to be deliverable off of the elongate body.

12. The tissue resection system according to claim 11 , wherein the tissue retractor is configured to extend through the selected tissue for resection to an outer surface of the body lumen, the plurality of arms positioned substantially parallel to the elongate body, and engaged with the outer surface when the plurality of arms is expanded radially.

13. The tissue resection system according to claim 12 , wherein the tissue retractor is configured to retract the arms substantially parallel to the elongate body while the anchoring mechanisms are engaged with the outer surface of the selected tissue for resection.

14. The tissue resection system according to claim 11 , wherein the tissue retractor is configured to retract proximally towards the elongate body such that the arms are receivable in the cavity.

15. The tissue resection system according to claim 11 , further comprising a sheath attached to the tissue retractor and extendable from the elongate body.

16. The tissue resection system according to claim 15 , wherein the sheath and the lumen are coaxial such that the sheath is extendable and retractable with respect to the elongate body along the lumen.

17. A method for resection of selected tissue in a body lumen of a patient, comprising:
positioning a distal end of a lumen in the body lumen of the patient to the selected tissue for resection;
extending a tissue resection device to the selected tissue for resection, the tissue resection device including an elongate body having a cavity at a distal end and a tissue retractor extendable distally from the distal end of the elongate body;
advancing the tissue retractor from an inner surface of the selected tissue to an outer surface of the selected tissue;
radially expanding a plurality of arms on an expansion mechanism of the tissue retractor;
engaging an anchoring mechanism on a tip of an end of each arm to the tissue selected for resection;
retracting the plurality of arms radially inward while the anchoring mechanisms are engaged to the selected tissue for resection, to capture the selected tissue;
retracting the tissue retractor in proximally toward the elongate body such that the captured tissue is received within the cavity of the elongate body;
resecting the selected tissue from the body lumen; and
delivering a tissue closure device off of an outer surface of the distal end of the elongate body.

18. The method according to claim 17 , wherein the expansion mechanism further includes a plurality of connectors each having a first end coupled to a sheath distally extendable from the elongate body, and a second end coupled to a respective arm such that the plurality of arms is radially expandable by articulation of the connectors.

19. The method according to claim 17 , further comprising closing remaining tissue of the body lumen with the tissue closure device.

Assignees

• Boston Scient Scimed Inc

Inventors

• Golden John B
• Valdes Caleb A
• Johnson Austin G
• Jicka Chris
• Scott Serena
• Ford Michael K
• Moore Kyle P
• Courtois Janice
• Somasundaram Prashanth

Classifications

• A61B2017/00668

  the implement being a tack or a staple · CPC title

• A61B2017/00269

  endoscopic mucosal resection EMR · CPC title

• A61B17/0218

  for minimally invasive surgery (A61B17/0281, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence) · CPC title

• A61B17/3478

  Endoscopic needles, e.g. for infusion (biopsy needles A61B10/0233; catheters with injection needles A61M25/0067) · CPC title

• A61B2017/00575

  for closure at remote site, e.g. closing atrial septum defects · CPC title