Apparatus and method for estimating bio-information

Patent metadata

Field	Value
Publication number	US-11389092-B2
Application number	US-202016816415-A
Country	US
Kind code	B2
Filing date	Mar 12, 2020
Priority date	Aug 20, 2019
Publication date	Jul 19, 2022
Grant date	Jul 19, 2022

Abstract

An apparatus for estimating bio-information according to an embodiment of the present disclosure includes a processor configured to obtain spectra from an object, obtain a component produced based on a change in pressure applied to the object, correct the spectra based on the obtained component produced based on the change in pressure, and estimate bio-information of the object based on the corrected spectra.

First claim

What is claimed is:

1. An apparatus for estimating bio-information, the apparatus comprising:
a processor configured to:
obtain spectra from an object;
perform principal component analysis (PCA) on the obtained spectra;
obtain a component, which is produced based on a change in pressure applied to the object, based on a result of performing the PCA;
correct the spectra based on the obtained component produced based on the change in pressure; and
estimate the bio-information of the object based on the corrected spectra.

2. The apparatus of claim 1 , wherein the processor is configured to:
obtain the component, produced based on the change in pressure, based on a shape of components which are analyzed by using the PCA.

3. The apparatus of claim 2 , wherein the processor is further configured to:
obtain the component, having a shape similar to a hemoglobin absorption peak among the components analyzed by using the PCA, as the component produced based on the change in pressure.

4. The apparatus of claim 2 , wherein the processor is further configured to:
obtain the component, having a spectrum shape similar to that of a component defined in a component database among the components analyzed by the PCA, as the component produced based on the change in pressure.

5. The apparatus of claim 1 , wherein the processor is further configured to:
obtain the component from a component database, based on the result of performing the PCA.

6. The apparatus of claim 5 , wherein the processor is further configured to:
collect spectra, obtained from a plurality of subjects, as training data;
perform the PCA on the collected training data; and
store a spectrum shape of principal components and principal component scores in the component database based on performing the PCA.

7. The apparatus of claim 6 , wherein the processor is further configured to:
perform the PCA on the obtained spectra from the object; and
update the component database by using the components analyzed by using the PCA.

8. The apparatus of claim 7 , wherein the processor is further configured to:
determine whether to update the component database based on at least one of the result of performing the PCA on the spectra obtained from the object, a generation date and an update date of the component database, and a collection environment of the training data.

9. The apparatus of claim 8 , further comprising a communication interface which, in response to determining to update the component database, receives data from an external device.

10. The apparatus of claim 1 , wherein the component corresponds to a first component, and the obtained spectra comprises the first component and a second component, and
wherein the processor is further configured to:
correct a spectrum change caused by the change in pressure by removing the second component, produced based on the change in pressure, from the obtained spectra; and
obtain the first component based on the corrected spectrum change.

11. The apparatus of claim 10 , wherein the processor is further configured to:
remove the second component from the obtained spectra by using a least square method.

12. The apparatus of claim 1 , wherein the processor is further configured to:
obtain the component, produced based on the change in pressure, based on spectra obtained during an initial pressure phase of an entire time period in which the spectra are obtained.

13. The apparatus of claim 1 , wherein the processor is further configured to:
obtain a noise-related component of the obtained spectra; and
correct the obtained spectra based on the component produced based on the change in pressure and the noise-related component.

14. The apparatus of claim 13 , wherein based on a correlation between principal component scores of principal components, which are analyzed by performing principal component analysis on at least one spectrum of the obtained spectra, and an estimated bio-information value which is estimated based on the at least one spectrum of the spectra, the processor is further configured to:
obtain at least one of the component produced based on the change in pressure and the noise-related component.

15. The apparatus of claim 1 , wherein the bio-information of the object includes at least one of blood glucose, triglyceride, cholesterol, calories, protein, carotenoid, lactate, and uric acid.

16. A method of estimating bio-information of an object, the method comprising:
obtaining spectra from the object;
performing principal component analysis (PCA) on the obtained spectra;
obtaining a component, which is produced based on a change in pressure applied to the object, based on a result of the PCA;
correcting the spectra based on the obtained component produced based on the change in pressure; and
estimating the bio-information of the object based on the corrected spectra.

17. The method of claim 16 , wherein the obtaining of the component produced based on the change in pressure comprises obtaining the component, produced based on the change in pressure, based on a shape of components which are analyzed by using the PCA.

18. The method of claim 17 , wherein the obtaining of the component produced due to the change in pressure comprises obtaining the component, having a shape similar to a hemoglobin absorption peak among the components analyzed by using the PCA, as the component produced based on the change in pressure.

19. The method of claim 17 , wherein the obtaining of the component produced based on the change in pressure comprises obtaining a component, having a spectrum shape similar to that of a component defined in a component database among the components analyzed by the PCA, as the component produced based on the change in pressure.

20. The method of claim 16 , wherein the obtaining of the component produced based on the change in pressure comprises obtaining the component from a component database, based on the result of performing the PCA.

21. The method of claim 16 , wherein the correcting of the spectra comprises correcting a spectrum change caused by the change in pressure by removing the component, produced based on the change in pressure, from the obtained spectra.

22. The method of claim 16 , wherein the obtaining of the component produced based on the change in pressure comprises obtaining the component, produced based on the change in pressure, based on spectra obtained during an initial pressure phase of an entire time period in which the spectra are obtained.

23. The method of claim 16 , further comprising:
obtaining a noise-related component of the obtained spectra,
wherein the correcting of the spectra comprises correcting the obtained spectra based on the component produced based on the change in pressure and the noise-related component.

24. The method of claim 23 , wherein the obtaining of the noise-related component comprises obtaining the noise-related component based on a correlation between principal component scores of principal components, which are analyzed by performing principal component analysis on at least one spectrum of the obtained spectra, and an estimated bio-information value which is estimated based on the at least one spectrum of the spectra.

25. A non-transitory computer-readable medium storing instructions, the instructions comprising:
one or more instructions that, when executed by one or more processors of a device, cause the

Assignees

• Samsung Electronics Co Ltd

Inventors

• Ahn Sung Mo
• Jang Hyeong Seok
• Kim Sang Kyu
• Park Jin Young
• Lee Jun Ho

Classifications

• A61B5/14551

  for measuring blood gases · CPC title

• G01N21/31 Primary

  Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry {(G01N21/72 takes precedence)} · CPC title

• A61B5/0053

  by applying pressure, e.g. compression, indentation, palpation, grasping, gauging · CPC title

• A61B5/681

  Wristwatch-type devices · CPC title

• A61B5/0075 Primary

  by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy (A61B5/0071 takes precedence) · CPC title