B-1,3-1,6-glucan powder, glucan-containing composition, method for producing B-1,3-1,6-glucan powder, inclusion complex, method for producing inclusion complex, and method for recovering guest molecule

Patent metadata

Field	Value
Publication number	US-11384159-B2
Application number	US-201816754952-A
Country	US
Kind code	B2
Filing date	Oct 10, 2018
Priority date	Oct 12, 2017
Publication date	Jul 12, 2022
Grant date	Jul 12, 2022

Abstract

Provided are a β-1,3-1,6-glucan powder having high solubility in water, a glucan-containing composition using the powder or the like, a method for producing the β-1,3-1,6-glucan powder, an inclusion complex, a method for producing the inclusion complex, and a method for recovering a guest molecule. The β-1,3-1,6-glucan powder has a saturation solubility in water at 25° C. of from 1.0 to 20.0 % by mass. The β-1,3-1,6-glucan powder is such that in a particle size distribution of β-1,3-1,6-glucans, determined by subjecting the β-1,3-1,6-glucan powder to dynamic light scattering measurements, a particle size of a peak representing a largest volume fraction is in a range from 5 nm to 15 nm, and a volume fraction of a peak outside of the particle size range from 5 nm to 15 nm is 30 % or less of the volume fraction of the peak having the largest volume fraction.

First claim

The invention claimed is:

1. A β-1,3-1,6-glucan powder with a saturation solubility in water at 25° C. of from 1.0 to 20.0% by mass,
wherein in a particle size distribution of β-1,3-1,6-glucans, determined by subjecting the β-1,3-1,6-glucan powder to dynamic light scattering measurements, a particle size of a peak representing a largest volume fraction is in a range of from 5 nm to less than 100 nm, and a volume fraction of a peak outside of the particle size range of from 5 nm to less than 100 nm is 30% or less of the volume fraction of the peak having the largest volume fraction.

2. A β-1,3-1,6-glucan powder wherein,
in a particle size distribution of β-1,3-1,6-glucans, determined by subjecting the β-1,3-1,6-glucan powder to dynamic light scattering measurements, a particle size of a peak representing a largest volume fraction is in a range of from 5 nm to 15 nm, and a volume fraction of a peak outside of the particle size range of from 5 nm to 15 nm is 30% or less of the volume fraction of the peak having the largest volume fraction.

3. A glucan-containing composition comprising water and β-1,3-1,6-glucans, wherein
the β-1,3-1,6-glucans are dissolved at a ratio of from 1.0 to 20.0% by mass in water; and
in a particle size distribution of β-1,3-1,6-glucans, determined by subjecting the composition to dynamic light scattering measurements, a particle size of a peak representing a largest volume fraction is in a range of from 5 nm to less than 100 nm, and a volume fraction of a peak outside of the particle size range of from 5 nm to 15 nm is 30% or less of the volume fraction of the peak having the largest volume fraction.

4. A β-1,3-1,6-glucan-containing composition comprising water and β-1,3-1,6-glucans, wherein,
in a particle size distribution of β-1,3-1,6-glucans, determined by subjecting the glucan-containing composition to dynamic light scattering measurements, a particle size of a peak representing a largest volume fraction is in a range from 5 nm to 15 nm, and a volume fraction of a peak outside of the particle size range from 5 nm to 15 nm is 30% or less of the volume fraction of the peak having the largest volume fraction.

5. A glucan-containing composition comprising the β-1,3-1,6-glucan powder described in claim 1 , and water.

6. The glucan-containing composition according to claim 5 , wherein the composition has a transmittance of light with a wavelength of 660 nm at 25° C. of 70% or more.

7. An inclusion complex in which a guest molecule is enveloped in β-1,3-1,6-glucan derived from a β-1,3-1,6-glucan powder according to claim 1 with a saturation solubility in water at 25° C. of from 1.0 to 20.0% by mass.

8. The inclusion complex according to claim 7 , wherein the inclusion complex is in powder form.

9. An inclusion complex in which a guest molecule is enveloped in β-1,3-1,6-glucan derived from the β-1,3-1,6-glucan powder described in claim 5 .

10. A method for producing an inclusion complex, the method comprising enveloping a guest molecule using the β-1,3-1,6-glucan powder described in claim 1 .

11. The method for producing an inclusion complex according to claim 10 , wherein the inclusion complex is in powder form.

12. A method for recovering a guest molecule, the method comprising enveloping a guest molecule using the β-1,3-1,6-glucan powder described in claim 1 .

13. A method for recovering a guest molecule, the method comprising enveloping a guest molecule using the β-1,3-1,6-glucan powder described in claim 5 .

14. A method for producing an inclusion complex, the method comprising enveloping a guest molecule using the β-1,3-1,6-glucan powder described in claim 5 .

Assignees

• Mitsubishi Gas Chemical Co
• Konan Gakuen

Inventors

• Kitahara Yoshitaka
• Koumoto Kazuya

Classifications

• A61K31/716

  Glucans · CPC title

• C08L5/00

  Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00 · CPC title

• A23V2002/00

  Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title

• C12P19/04 Primary

  Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds · CPC title

• C08B37/0024 Primary

  beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof · CPC title