Polypeptide and method of producing IMP using the same

US11384124B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11384124-B2
Application numberUS-201916346725-A
CountryUS
Kind codeB2
Filing dateJan 4, 2019
Priority dateJan 4, 2018
Publication dateJul 12, 2022
Grant dateJul 12, 2022

How to read this patent

A practical reading order for non-experts. Skip the full description unless you need deep technical detail.

  1. Title

    What the patent document calls the invention.

  2. Abstract

    A short plain-language summary of the technical disclosure.

  3. Assignees and inventors

    Who owns or filed the patent and who is credited as inventor.

  4. Key dates

    Filing, priority, publication, and grant dates set the timeline.

  5. First independent claim

    The legal scope of protection — read this for what is actually claimed.

  6. CPC / IPC classifications

    Technology tags used to group this patent with similar filings.

  7. Citations and related patents

    Prior art links and similar publications in this corpus.

Abstract

Official abstract text for this publication.

The present disclosure relates to a novel protein variant having an activity of exporting 5′-inosine monophosphate, a microorganism comprising the protein variant, and a method for preparing 5′-inosine monophosphate using the microorganism.

First claim

Opening claim text (preview).

The invention claimed is: 1. A protein variant capable of exporting 5′-inosine monophosphate, having at least 90% sequence identity to SEQ ID NO: 2, and comprising one or more substitutions selected from the group consisting of: a substitution of the 123 rd amino acid of SEQ ID NO: 2 with cysteine, a substitution of the 243 rd amino acid of SEQ ID NO: 2 with valine, a substitution of the 387 th amino acid of SEQ ID NO: 2 with threonine, a substitution of the 405 th amino acid of SEQ ID NO: 2 with tyrosine, a substitution of the 413 th amino acid of SEQ ID NO: 2 with threonine, and a substitution of the 458 th amino acid of SEQ ID NO: 2. 2. The protein variant according to claim 1 , wherein the protein variant further comprises a substitution of the 2 nd amino acid of SEQ ID NO: 2 with isoleucine, a substitution of the 64 th amino acid of SEQ ID NO: 2 with glutamic acid or aspartate, or a combination thereof.

Assignees

Inventors

Classifications

  • C07K14/34Primary

    from Corynebacterium (G) · CPC title

  • C12N15/77Primary

    for Corynebacterium; for Brevibacterium · CPC title

  • having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide · CPC title

  • Corynebacterium · CPC title

  • having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides · CPC title

Patent family

Related publications grouped by family.

External sources

Frequently asked questions

Answers are generated from the same data shown on this page.

What does patent US11384124B2 cover?
The present disclosure relates to a novel protein variant having an activity of exporting 5′-inosine monophosphate, a microorganism comprising the protein variant, and a method for preparing 5′-inosine monophosphate using the microorganism.
Who is the assignee on this patent?
Cj Cheiljedang Corp
What technology area does this patent fall under?
Primary CPC classification C07K14/34. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Jul 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 5 related publications on this page (citations in our corpus or others sharing the same primary CPC).