Six-membered C—N-bonded aryl sulphide and aryl sulphoxide derivatives as pesticides
US-10039282-B2 · Aug 7, 2018 · US
US11384124B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11384124-B2 |
| Application number | US-201916346725-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 4, 2019 |
| Priority date | Jan 4, 2018 |
| Publication date | Jul 12, 2022 |
| Grant date | Jul 12, 2022 |
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The present disclosure relates to a novel protein variant having an activity of exporting 5′-inosine monophosphate, a microorganism comprising the protein variant, and a method for preparing 5′-inosine monophosphate using the microorganism.
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The invention claimed is: 1. A protein variant capable of exporting 5′-inosine monophosphate, having at least 90% sequence identity to SEQ ID NO: 2, and comprising one or more substitutions selected from the group consisting of: a substitution of the 123 rd amino acid of SEQ ID NO: 2 with cysteine, a substitution of the 243 rd amino acid of SEQ ID NO: 2 with valine, a substitution of the 387 th amino acid of SEQ ID NO: 2 with threonine, a substitution of the 405 th amino acid of SEQ ID NO: 2 with tyrosine, a substitution of the 413 th amino acid of SEQ ID NO: 2 with threonine, and a substitution of the 458 th amino acid of SEQ ID NO: 2. 2. The protein variant according to claim 1 , wherein the protein variant further comprises a substitution of the 2 nd amino acid of SEQ ID NO: 2 with isoleucine, a substitution of the 64 th amino acid of SEQ ID NO: 2 with glutamic acid or aspartate, or a combination thereof.
from Corynebacterium (G) · CPC title
for Corynebacterium; for Brevibacterium · CPC title
having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide · CPC title
Corynebacterium · CPC title
having a condensed ring system containing a six-membered ring having two nitrogen atoms in the same ring, e.g. purine nucleosides · CPC title
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