Device and method for evaluating amount of biological sample in a specimen container

Patent metadata

Field	Value
Publication number	US-11378435-B2
Application number	US-201515511982-A
Country	US
Kind code	B2
Filing date	Sep 16, 2015
Priority date	Sep 17, 2014
Publication date	Jul 5, 2022
Grant date	Jul 5, 2022

Abstract

An apparatus and method are provided to evaluate an amount of a biological sample in a specimen container. A fixture has a bottom surface configured to support a specimen container. A reference indicator is disposed at a predetermined height relative to the bottom surface. The reference indicator is configured to facilitate a visual comparison of the reference indicator with a height of a volume of a biological sample in the specimen container.

First claim

What is claimed is:

1. An apparatus for evaluating an amount of biological sample in a specimen container, comprising:
a removable member comprising a protruding portion on one face of the removable member and a reference indicator disposed on the removable member on another face of the removable member directly opposite the one face;
a fixture with a bottom surface configured to support a specimen container, wherein the fixture further comprises a holder for holding receiving the protruding portion of the removable member, the holder having a bottom support portion;
wherein a lower end of the protruding portion is configured to rest on top of the bottom support portion of the holder such that, when the removable member is held in the holder, the holder positions the removable member in a predetermined position relative to the bottom surface of the fixture and the reference indicator is positioned at a predetermined height relative to the bottom surface,
wherein the lower end of the protruding portion is an end of the removable member that is closest to the bottom surface,
wherein the reference indicator is an indicium that identifies a location above the bottom support portion of the holder and provides a volume measurement of a biological sample in the specimen container, wherein the volume measurement is based on a biological sample distance of the specimen container above the bottom surface of the fixture,
wherein the reference indicator is configured to facilitate a visual comparison of the reference indicator with a height of a volume of the biological sample in the specimen container to provide the volume measurement,
wherein the holder is at least one of a slot and a sleeve having a shape corresponding to a shape of the protruding portion of the removable member.

2. The apparatus of claim 1 , wherein the bottom surface comprises a flat surface configured to support a specimen container with a flat bottom.

3. The apparatus of claim 1 , wherein the bottom surface comprises a curved surface configured to support a specimen container with a curved bottom.

4. The apparatus of claim 1 , wherein the fixture includes a support, wherein the support is configured to support a substantially vertical surface of the specimen container.

5. The apparatus of claim 1 , wherein the fixture includes a spirit level configured to indicate an orientation of the bottom surface.

6. The apparatus of claim 1 , wherein the removable member comprises an indicator to identify a type of specimen container to be used with the removable member.

7. The apparatus of claim 1 , wherein the reference indicator is at least one of a reference line, an arrow, and a top surface of the fixture.

8. The apparatus of claim 1 , further comprising a light source configured to illuminate the specimen container to facilitate the visual comparison of the reference indicator with the height of the volume of biological sample in the specimen container.

9. The apparatus of claim 1 , wherein the bottom surface is transparent.

10. The apparatus of claim 1 , further comprising a second reference indicator located at a second predetermined height relative to the bottom surface.

11. The apparatus of claim 10 , wherein the area above the reference indicator indicates a volume of biological sample suitable for a first condition, and the area between the reference indicator and the second reference indicator indicates a volume of biological sample suitable for a second condition.

12. A method of evaluating an amount of biological sample in a specimen container, the method comprising:
disposing the specimen container in a fixture having a bottom surface configured to support the specimen container, wherein the fixture further comprises a holder for receiving a removable member having a protruding portion on one face of the removable member and a reference indicator disposed on the removable member on another face of the removable member directly opposite the one face;
disposing the protruding portion of the removable member in the holder such that a lower end of the protruding portion rests on top of a bottom support portion of the holder, the holder positions the removable member in a predetermined position relative to the bottom surface of the fixture, and the reference indicator is positioned at a predetermined height relative to the bottom surface,
wherein the holder is at least one of a slot and a sleeve having a shape corresponding to a shape of the protruding portion of the removable member,
wherein the lower end of the protruding portion is an end of the removable member that is closest to the bottom surface; and
visually comparing a height of a volume of a biological sample in the specimen container with the reference indicator to provide a volume measurement of biological sample contained within the specimen container,
the reference indicator comprising an indicium that identifies a location above the bottom support portion of the holder and provides the volume measurement of the biological sample in the specimen container, wherein the volume measurement is based on a biological sample distance of the specimen container above the bottom surface of the fixture.

13. The method of claim 12 , further comprising placing a substantially vertical surface of the specimen container in contact with a support of the fixture that is configured to support a substantially vertical surface of the specimen container.

14. The method of claim 12 , further comprising leveling the bottom surface.

15. The method of claim 12 , further comprising illuminating the specimen container with a light source.

16. The method of claim 12 , further comprising relatively positioning the reference indicator and an eye level of a user such that the reference indicator and the eye level of the user are located at substantially the same height, wherein visually comparing the height of the volume of the biological sample in the specimen container with the reference indicator comprises visually comparing a portion of a meniscus formed by the biological sample to the reference indicator.

Assignees

• Quest Diagnostics Invest Inc

Inventors

• Amendt Christine
• Bedrosian Sevag
• Love Gordon
• Daniyelyan Mkrtich
• Torrero Miguel

Classifications

• G01F11/262

  for liquid or semi-liquid · CPC title

• B01L3/00

  Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers · CPC title

• G01F23/02 Primary

  by gauge glasses or other apparatus involving a window or transparent tube for directly observing the level to be measured or the level of a liquid column in free communication with the main body of the liquid · CPC title

• G01N30/00

  Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography {or field flow fractionation} (G01N3/00, G01N5/00, G01N7/00, G01N9/00, G01N11/00, G01N13/00, G01N15/00, G01N17/00, G01N19/00, G01N21/00, G01N22/00, G01N23/00, G01N24/00, G01N25/00, G01N27/00, G01N29/00 take precedence) · CPC title

• B01L9/06

  Test-tube stands; Test-tube holders · CPC title