Biodegradable iron-containing compositions, methods of preparing and applications therefor

Patent metadata

Field	Value
Publication number	US-11376349-B2
Application number	US-201314045011-A
Country	US
Kind code	B2
Filing date	Oct 3, 2013
Priority date	Oct 5, 2012
Publication date	Jul 5, 2022
Grant date	Jul 5, 2022

Abstract

Biodegradable compositions containing from 10.0 to 95.0 weight percent iron for use in preparing medical devices. These biodegradable compositions exhibit properties that make them suitable for use as medical devices for implantation into a body of a patient. The compositions also include one or more elements selected from manganese, magnesium, zirconium, zinc and calcium. The compositions can be prepared using a high energy milling technique and high energy mechanical alloying followed by compaction and sintering, film deposition techniques, such as, pulsed laser deposition (PLD), as well as melting, casting, homogenization and extrusion methods. The resulting compositions and the medical devices formed therefrom are useful in various surgical procedures, such as but not limited to orthopedic, craniofacial and cardiovascular.

First claim

The invention claimed is:

1. A biodegradable iron-based alloy, consisting of:
2.9 weight percent of magnesium;
5.8 weight percent of calcium;
38.1 weight percent of zinc; and
53.2 weight percent of iron.

Assignees

• Univ Of Pittsburgh—Of The Commonwealth System Of Higher Education

Inventors

• Kumta Prashant N
• Chung Sung Jae
• Saha Partha
• Velikokhatnyi Oleg
• Datta Moni Kanchan
• Hong Dae Ho
• Chou Da-Tren

Classifications

• C22C45/02

  with iron as the major constituent · CPC title

• C22C38/14

  containing titanium or zirconium · CPC title

• C22C33/10

  including procedures for adding magnesium · CPC title

• C22C38/04

  containing manganese · CPC title

• A61L31/148

  Materials at least partially resorbable by the body · CPC title