Genetically modified bacillus subtilis strain and use as a live delivery and production system
US-2024390433-A1 · Nov 28, 2024 · US
US11375734B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11375734-B2 |
| Application number | US-201615568364-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 21, 2016 |
| Priority date | Apr 21, 2015 |
| Publication date | Jul 5, 2022 |
| Grant date | Jul 5, 2022 |
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The compositions, method, system, and process of the invention provide increased circulating lipids, including serum triglycerides, in animals by utilizing oleaginous microorganisms as an oral supplement for the animals to increase available energy, enhance probiotics health, and provide enhanced immune system protection against pathogens in the animals.
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What is claimed is: 1. A method of improving the nutritional supplementation profile of an animal in need thereof, the method comprising: forming an oral supplement composition comprising a delivery media combined with at least one oleaginous microorganism; administering said oral supplement composition to the animal in an amount effective to improve the nutritional supplementation profile in the animal, wherein the oral supplement composition comprises at least about 20% of its cellular weight as lipid; and increasing a level of circulating triglycerides of the animal through the administration of the composition to the animal to enhance an immunity response of the animal, and wherein the nutritional supplementation includes nutritional, energy, or immune system supplementation, or a combination thereof, for the animal and wherein the at least one oleaginous microorganism is enteric bacteria Enterobacter cloacae strain JD6301, Enterobacter cloacae strain JD8715, or a combination thereof. 2. The method of claim 1 , wherein the delivery media is an orally ingestible solid, liquid, or combination thereof. 3. A method of increasing triacylglyceride concentration and improving the nutritional supplementation profile of an animal in need thereof, the method comprising: forming an oral supplement composition comprising a delivery media combined with at least one oleaginous microorganism; and administering said oral supplement composition to the animal in an amount effective to improve the nutritional supplementation profile in the animal, wherein the oral supplement composition comprises at least about 20% of its cellular weight as lipid, wherein the nutritional supplementation includes nutritional, energy, or immune system supplementation, or a combination thereof, for the animal, and wherein the at least one oleaginous microorganism is enteric bacteria Enterobacter cloacae strain JD6301, Enterobacter cloacae strain JD8715, or a combination thereof. 4. The method of claim 3 , wherein the delivery media is an orally ingestible solid, liquid, or combination thereof.
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