Heat exchanger, oxygenator, and method of manufacturing a heat exchanger

Patent metadata

Field	Value
Publication number	US-11364327-B2
Application number	US-201916273495-A
Country	US
Kind code	B2
Filing date	Feb 12, 2019
Priority date	Aug 31, 2016
Publication date	Jun 21, 2022
Grant date	Jun 21, 2022

Abstract

A heat exchanger for an oxygenator device has multiple hollow fiber membranes that each have a hollow portion through which a heat medium passes, wherein the fibers are wound as a cylinder body. Each of the hollow fiber membranes follows a path between opposing ends of the cylinder body which is tilted with respect to a central axis of the cylinder body and is wound around the central axis of the cylinder body, wherein a tilt angle θ with respect to the central axis ranges from 22° to smaller than 67°, and wherein a constituent material of each of the hollow fiber membranes has a Young's modulus E ranging from 2.6 GPa to 0.07 GPa. During winding, the hollow fiber membranes are stretched according to a stretching rate between 0.5% and 3.0% and then fixed at the ends to maintain the stretching.

First claim

What is claimed is:

1. A heat exchanger for an oxygenator, comprising:
a cylinder member;
multiple hollow fiber membranes that each have a hollow portion through which a heat medium passes, and exhibiting a shape of a cylinder body as a whole shape in which the multiple hollow fiber membranes are each wound onto the cylinder member along a path which is tilted with respect to a central axis of the cylinder according to a tilt angle θ with respect to the central axis of the cylinder member which ranges from 22° to smaller than 67°, and wherein a constituent material of each of the hollow fiber membranes has a Young's modulus E of 2.6 GPa or smaller; and
fixing bodies at opposing sides of the cylinder member fixing opposite ends of each of the hollow fiber membranes such that each hollow fiber membrane is fixed under tension that stretches each hollow fiber membrane at a stretching rate between 0.5% and 3.0%, wherein stretching of the hollow fiber membranes reduces an outer diameter of the hollow fiber membranes and a blood filling amount of the heat exchanger is accordingly reduced.

2. The heat exchanger according to claim 1 ,
wherein the Young's modulus E is 0.07 GPa or greater.

3. The heat exchanger according to claim 1 ,
wherein the constituent material of each of the hollow fiber membranes is a polyamide-based resin material or a polyester-based resin material.

4. The heat exchanger according to claim 1 ,
wherein each hollow fiber membrane has an outer diameter of 1 mm or smaller in a natural state without stretching.

5. The heat exchanger according to claim 1 ,
wherein the fixing bodies are comprised of potting material applied over the respective ends of the hollow fiber membranes.

6. The heat exchanger according to claim 1 ,
wherein the stretching rate is between 0.5% and 1.0%.

7. A method of manufacturing a heat exchanger including multiple hollow fiber membranes that each have a hollow portion through which a heat medium passes, and exhibiting a shape of a cylinder body as a whole shape disposed over a cylinder member, the method comprising:
winding each of the hollow fiber membranes around a central axis of the cylinder following a path which is tilted at a tilt angle θ with respect to the central axis of the cylinder body while simultaneously tensioning the hollow fiber membranes in a pulled state wherein the hollow fiber membrane is stretched in a longitudinal direction of the hollow fiber membrane at a stretching rate of each of the hollow fiber membranes ranging from 0.5% to 3%, wherein tilt angle θ with respect to the central axis of the cylinder body of each of the hollow fiber membranes ranges from 22° to smaller than 67°, and wherein a constituent material of each of the hollow fiber membranes has a Young's modulus E of 2.6 GPa or smaller; and
fixing the hollow fiber membranes as opposing ends of the cylinder member to maintain the stretching of the hollow fiber membranes.

8. The method of manufacturing a heat exchanger according to claim 7 ,
wherein the Young's modulus E is 0.07 GPa or greater.

9. The method of manufacturing a heat exchanger according to claim 7 ,
wherein the constituent material of each of the hollow fiber membranes is a polyamide-based resin material or a polyester-based resin material.

10. The method of manufacturing a heat exchanger according to claim 7 ,
wherein the hollow fiber membrane has an outer diameter of 1 mm or smaller in a natural state without stretching.

11. The method of manufacturing a heat exchanger according to claim 7 ,
wherein in the winding step, each of the hollow fiber membranes is wound by reciprocating each of the hollow fiber membranes on an outer peripheral portion of the cylinder member in a central axis direction; and
wherein in the winding step, when each of the hollow fiber membranes is reciprocating, a turned-back portion is formed by causing the hollow fiber membrane to be turned back on both one end and the other end of the cylinder member, and the fixing step is comprised of winding a fixing string around the central axis of the cylinder member in the vicinity of the turned-back portion in an overlapping manner.

12. The method of manufacturing a heat exchanger according to claim 11 ,
wherein a stepped portion having a reduced outer diameter is formed at both ends of the cylinder member; and
wherein the fixing string is disposed in a manner overlapping the stepped portions at both the ends.

13. The method of manufacturing a heat exchanger according to claim 11 ,
wherein respective grooves are formed along a circumferential direction recessed from both the ends of the cylinder member; and
wherein the fixing string is disposed in a manner overlapping the grooves at both the ends.

14. The method of manufacturing a heat exchanger according to claim 7 ,
wherein the stretching rate is between 0.5% and 1.0%.

15. A gas exchanger for an oxygenator, comprising:
a cylinder member;
multiple hollow fiber membranes that each have a hollow portion through which a gas passes, and exhibiting a shape of a cylinder body as a whole shape in which the multiple hollow fiber membranes are each wound onto the cylinder member along a path which is tilted with respect to a central axis of the cylinder according to a tilt angle θ with respect to the central axis of the cylinder member which ranges from 22° to smaller than 67°, and wherein a constituent material of each of the hollow fiber membranes has a Young's modulus E between 0.07 GPa and 2.6 GPa; and
fixing bodies at opposing sides of the cylinder member fixing opposite ends of each of the hollow fiber membranes such that each hollow fiber membrane is fixed under tension that stretches each hollow fiber membrane at a stretching rate between 0.5% and 3.0%, wherein stretching of the hollow fiber membranes reduces an outer diameter of the hollow fiber membranes and a blood filling amount of the gas exchanger is accordingly reduced.

16. The gas exchanger according to claim 15 ,
wherein the constituent material of each of the hollow fiber membranes is a polyamide-based resin material or a polyester-based resin material, and wherein each hollow fiber membrane has an outer diameter of 1 mm or smaller in a natural state without stretching.

17. The gas exchanger according to claim 15 ,
wherein the fixing bodies are comprised of potting material applied over the respective ends of the hollow fiber membranes.

18. The gas exchanger according to claim 15 ,
wherein the stretching rate is between 0.5% and 1.0%.

Assignees

• Terumo Corp

Inventors

• Gyoten Akira
• Hiraguchi Ryuji

Classifications

• A61M1/1698 Primary

  Blood oxygenators with or without heat-exchangers (intracorporal A61M1/1678; manufacturing of membranes therefor B01D67/00; semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi-permeable membranes characterised by their material B01D71/00) · CPC title

• B01D2313/60

  Specific sensors or sensor arrangements · CPC title

• B01D2313/221

  Heat exchangers · CPC title

• B01D63/022

  Encapsulating hollow fibres · CPC title

• B01D71/48

  Polyesters · CPC title