Non-invasive method for focal deep-brain stimulation equipment and methodologies
US-2018368726-A1 · Dec 27, 2018 · US
US11357997B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11357997-B2 |
| Application number | US-201816120974-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 4, 2018 |
| Priority date | Sep 1, 2017 |
| Publication date | Jun 14, 2022 |
| Grant date | Jun 14, 2022 |
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Methodologies and mechanisms are provided for introducing one or more magnetizable particles introduced non-invasively into one or more body structures containing nervous tissue in a subject, directing, guiding, transporting, focusing and/or concentrating the one or more particles using at least one image-guidance component in proximity to the one or more body structures which can direct the one or more particles within the one or more body structures, and modulating, using at least one activation component, the one or more particles to modulate neuronal function in the one or more body structures of the subject.
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What is claimed: 1. A method of treating a patient with a neurological disorder with noninvasive administration of one or more magnetizable particles, wherein the method comprises: performing image-guided magnetic delivery of the one or more magnetizable particles to a neural structure of a subject; and modulating the neural structure with at least one activation component so as to treat the neurological disorder. 2. The method of claim 1 , wherein the neurological disorder is an addiction disorder. 3. The method of claim 1 , wherein the modulation is activated by an authorization code that is not known to the subject. 4. The method of claim 1 , wherein neuromodulation is implemented by moving the one or more magnetizable particles in the neural structure. 5. The method of claim 1 , wherein the one or more magnetizable particles degrade in less than one month. 6. The method of claim 1 , wherein the one or more magnetizable particles degrade in less than one year. 7. The method of claim 1 , wherein the at least one activation component weighs less than 10 kilograms. 8. The method of claim 1 , wherein the image-guided magnetic delivery of the one or more magnetizable particles to the subject's neural structure is performed using at least one image-guidance component positioned in proximity to the neural structure within the subject, wherein the at least one image-guidance component is configured to direct the one or more magnetizable particles within the one or more body structures. 9. The method of claim 8 , wherein the at least one image-guidance component comprises an MRI system that includes at least one magnetic coil. 10. The method of claim 8 , wherein the MRI system is a single-sided MRI system. 11. The method of claim 8 , wherein the MRI system includes a plurality of electropermanent sections. 12. The method of claim 8 , wherein the MRI system generates pulse sequences wherein the MRI has pulse sequences whose rise-time, fall-time, or duration are less than 10 microseconds long. 13. The method of claim 8 , wherein the MRI system includes at least one magnetic coil generates a magnetic field that rises or falls in such short a time as not to cause nerve stimulation of the subject. 14. The method of claim 13 , wherein the at least one magnetic coil generates a magnetic field that rises or falls in less than 10 microseconds.
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