Cylindrical microelectrode array for neural stimulation and recording

Patent metadata

Field	Value
Publication number	US-11357975-B2
Application number	US-201615580640-A
Country	US
Kind code	B2
Filing date	Jun 9, 2016
Priority date	Jun 9, 2015
Publication date	Jun 14, 2022
Grant date	Jun 14, 2022

Abstract

A cylindrical microelectrode array having an elongated cylindrical core, and a multilayer structure conformally folded around and affixed to the cylindrical core so as to extend between opposite ends of the core. The multilayer structure has integrated sections including an electrode section with electrodes exposed through electrically insulating layers, a connector section with conductive bond pads for interfacing with external electronics, and a cable section with conductive traces encapsulated in electrically insulating layers and which connect between the electrodes and their corresponding bond pads. The array may be fabricated using a planar multilayer structure having the electrode, connector, and cable sections, and conformally folding the multilayer structure around and affixing to the cylindrical core. The cable section in particular may be conformally coiled around and affixed to the cylindrical core so that the electrical conduits helically extend between the connector and electrode sections.

First claim

We claim:

1. A cylindrical microelectrode array, comprising:
an elongated cylindrical core; and
a multilayer structure conformally folded around and affixed to the cylindrical core so as to extend between opposite ends thereof, said multilayer structure having integrated sections comprising:
a multilayer electrode section having a plurality of electrodes exposed through electrically insulating layers, and conformally folded around and affixed to a first one of the opposite ends of said elongated cylindrical core,
a multilayer connector section having a plurality of conductive bond pads exposed through electrically insulating layers for interfacing with external electronics, and conformally folded around and affixed to a second one of the opposite ends of said elongated cylindrical core, and
a multilayer cable section connecting between the multilayer electrode and connector sections and conformally folded around and affixed to the elongated cylindrical core between the opposite ends thereof, and having a plurality of conductive traces encapsulated in electrically insulating layers and which connect between the electrodes and their corresponding bond pads.

2. The cylindrical microelectrode array of claim 1 ,
wherein the multilayer electrode section of the multilayer structure has a substantially rectangular planar layout so that opposite longitudinal edges of the multilayer electrode section connect to form a seam when conformally folded around and affixed to the cylindrical core.

3. The cylindrical microelectrode array of claim 1 ,
wherein the multilayer cable section of the multilayer structure is helically coiled around the cylindrical core.

4. The cylindrical microelectrode array of claim 1 ,
wherein both the multilayer electrode and cable sections of the multilayer structure are helically coiled around the cylindrical core.

5. The cylindrical microelectrode array of claim 1 ,
wherein the multilayer cable section of the multilayer structure has a planar layout that is selected from the group consisting of polygonal spiral, non-polygonal spiral, and serpentine with switchbacks.

6. The cylindrical microelectrode array of claim 1 ,
wherein the multilayer cable section includes a plurality of multilayer strands extending between the multilayer electrode and connector regions, with each strand having at least one insulated conductive trace.

7. The cylindrical microelectrode array of claim 1 ,
wherein the elongated cylindrical core is hollow to receive a stylet therein.

8. A method of fabricating a cylindrical microelectrode array, comprising:
providing a planar multilayer structure having a multilayer electrode section with a plurality of electrodes exposed through electrically insulating layers, and multilayer connector section having conductive bond pads for interfacing with external electronics; and a multilayer cable section having insulated electrical conduits connecting between the bond pads of the multilayer connector section with the electrodes of the multilayer electrode section; and
conformally folding the planar multilayer structure around and affixing to a cylindrical core so that the multilayer electrode section is conformally folded around and affixed to a first one of the opposite ends of said elongated cylindrical core, the multilayer connector section is conformally folded around and affixed to a second one of the opposite ends of said elongated cylindrical core, and the multilayer cable section is conformally folded around and affixed to the elongated cylindrical core between the opposite ends thereof, and the plurality of electrodes are distributed radially and/or axially along a cylindrical axis of the cylinder core.

9. The method of claim 8 ,
wherein the step of conformally folding the planar multilayer structure around and affixing to the cylindrical core includes helically coiling the multilayer cable section around the cylindrical core.

Assignees

• L Livermore Nat Security Llc

Inventors

• Shah Kedar G
• Chen Supin
• Felix Sarah H
• Pannu Satinderpall S
• Patra Susant
• Tolosa Vanessa
• Tooker Angela C
• Jones Jason

Classifications

• A61N1/0551 Primary

  Spinal or peripheral nerve electrodes · CPC title

• A61B2562/046

  in a matrix array · CPC title

• A61N1/0529

  Electrodes for brain stimulation · CPC title

• A61B2562/125

  characterised by the manufacture of electrodes · CPC title

• A61B5/24 Primary

  Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof · CPC title