Compositions and methods for cancer immunotherapy
US-9770467-B2 · Sep 26, 2017 · US
US11339188B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11339188-B2 |
| Application number | US-202016781352-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 4, 2020 |
| Priority date | Feb 17, 2017 |
| Publication date | May 24, 2022 |
| Grant date | May 24, 2022 |
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Provided herein are compounds useful for the treatment of cancer.
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We claim: 1. A compound or pharmaceutically acceptable salt thereof, selected from the group consisting of: 2. The compound or pharmaceutically acceptable salt of claim 1 , wherein the compound or pharmaceutically acceptable salt is Compound 2 or a pharmaceutically acceptable salt thereof. 3. The compound or pharmaceutically acceptable salt of claim 2 , wherein the compound is selected, and wherein the compound is Compound 2. 4. The compound or pharmaceutically acceptable salt of claim 2 , wherein the pharmaceutically acceptable salt is selected, and wherein the pharmaceutically acceptable salt is a diammonium salt of Compound 2. 5. A pharmaceutical composition comprising a compound or pharmaceutically acceptable salt of claim 2 and a pharmaceutically acceptable excipient. 6. The compound or pharmaceutically acceptable salt of claim 1 , wherein the compound or pharmaceutically acceptable salt is Compound 6 or a pharmaceutically acceptable salt thereof. 7. The compound or pharmaceutically acceptable salt of claim 6 , wherein the compound is selected, and wherein the compound is Compound 6. 8. The compound or pharmaceutically acceptable salt of claim 6 , wherein the pharmaceutically acceptable salt is selected, and wherein the pharmaceutically acceptable salt is a diammonium salt of Compound 6. 9. A pharmaceutical composition comprising a compound or pharmaceutically acceptable salt of claim 6 and a pharmaceutically acceptable excipient. 10. The compound or pharmaceutically acceptable salt of claim 1 , wherein the compound or pharmaceutically acceptable salt is Compound 26 or a pharmaceutically acceptable salt thereof. 11. The compound or pharmaceutically acceptable salt of claim 10 , wherein the compound is selected, and wherein the compound is Compound 26. 12. The compound or pharmaceutically acceptable salt of claim 10 , wherein the pharmaceutically acceptable salt is selected, and wherein the pharmaceutically acceptable salt is a diammonium salt of Compound 26. 13. A pharmaceutical composition comprising a compound or pharmaceutically acceptable salt of claim 10 and a pharmaceutically acceptable excipient. 14. The compound or pharmaceutically acceptable salt of claim 10 , wherein the pharmaceutically acceptable salt is selected, and wherein the pharmaceutically acceptable salt is a di-triethylamine salt of Compound 26. 15. The compound or pharmaceutically acceptable salt of claim 1 , wherein the compound or pharmaceutically acceptable salt is Compound 29 or a pharmaceutically acceptable salt thereof. 16. The compound or pharmaceutically acceptable salt of claim 15 , wherein the compound is selected, and wherein the compound is Compound 29. 17. The compound or pharmaceutically acceptable salt of claim 15 , wherein the pharmaceutically acceptable salt is selected, and wherein the pharmaceutically acceptable salt is a diammonium salt of Compound 29. 18. A pharmaceutical composition comprising a compound or pharmaceutically acceptable salt of claim 15 and a pharmaceutically acceptable excipient.
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