Pharmaceutical compositions
US-11872314-B2 · Jan 16, 2024 · US
US11337925B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11337925-B2 |
| Application number | US-201615145337-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 3, 2016 |
| Priority date | Jun 30, 2005 |
| Publication date | May 24, 2022 |
| Grant date | May 24, 2022 |
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A preparation in the form of a powder containing: (a) at least one carotenoid, (b) at least one modified starch, and (c) sucrose; wherein the at least one carotenoid is present in the powder in an amount of 1 to 25% by weight, based on the weight of the powder; and wherein the at least one carotenoid and the sucrose are present in the powder in a ratio by weight of 1:2 to 1:80.
Opening claim text (preview).
We claim: 1. A preparation in powder form comprising: (a) β-carotene, (b) at least one modified starch, and (c) sucrose; wherein the at least one carotenoid is present in the powder in an amount of 1 to 25% by weight, based on the weight of the powder; and wherein the at least one carotenoid and the sucrose are present in the powder in a ratio by weight of 1:2 to 1:80 and said at least one modified starch is present in an amount from 5 to 30% by weight, based on the powder, and wherein the β-carotene has a degree of crystallinity in the range from 90 to 99% determined by X-ray diffraction. 2. The preparation according to claim 1 , which further comprises component d) from 0.1 to 10% by weight of an antioxidant based on the total mass of the preparation in powder form. 3. A composition comprising: an additive amount of the preparation according to claim 1 ; and a component selected from the group consisting of human foods, dietary supplements, animal feeds, pharmaceutical preparations and cosmetic preparations. 4. The preparation according to claim 1 , wherein the β-carotene is present in the powder in an amount of 2 to 20% by weight, based on the weight of the powder; and wherein the α-carotene and the sucrose are present in the powder in a ratio by weight of 1:3 to 1:40. 5. The preparation according to claim 1 , wherein the β-carotene is present in the powder in an amount of 5 to 15% by weight, based on the weight of the powder; and wherein the β-carotene and the sucrose are present in the powder in a ratio by weight of 1:4 to 1:18. 6. A preparation in powder form comprising: (a) at least one carotenoid, (b) at least one modified starch, and (c) sucrose; wherein the at least one carotenoid is present in the powder in an amount of 1 to 25% by weight, based on the weight of the powder; and wherein the at least one carotenoid and the sucrose are present in the powder in a ratio by weight of 1:2 to 1:80 and said at least one modified starch is present in an amount from 5 to 30% by weight, based on the powder, and wherein the carotenoid has a degree of crystallinity in the range from 90 to 99% determined by X-ray diffraction, wherein the at least one carotenoid is present in the powder in an amount of 8 to 13% by weight, based on the weight of the powder; and wherein the at least one carotenoid and the sucrose are present in the powder in a ratio by weight of 1:5 to 1:10. 7. The preparation according to claim 1 , wherein the β-carotene is present in the powder in an amount of 8 to 13% by weight, based on the weight of the powder; and wherein the β-carotene and the sucrose are present in the powder in a ratio by weight of 1:5 to 1:10. 8. The preparation according to claim 1 , wherein said at least one modified starch is present in an amount from 8 to 26% by weight. 9. The preparation according to claim 7 , which further comprises component d) from 1 to 2% by weight of an antioxidant based on the total mass of the preparation in powder form and said at least one modified starch is present in an amount from 8 to 26% by weight. 10. The preparation according to claim 1 , which further comprises component d) from 1 to 2% by weight of an antioxidant based on the total mass of the preparation in powder form. 11. A composition comprising: an additive amount of the preparation according to claim 9 ; and a component selected from the group consisting of human foods, dietary supplements, animal feeds, pharmaceutical preparations and cosmetic preparations. 12. The preparation according to claim 9 , wherein the β-carotene and the sucrose are present in the powder in a ratio by weight of 1:6.6 to 1:7.2. 13. The preparation according to claim 12 , wherein the β-carotene has a degree of crystallinity in the range from 95 to 99% determined by X-ray diffraction. 14. The preparation according to claim 1 , wherein the preparation is prepared by the process which consists essentially of: i) suspending said β-carotene a) in an aqueous molecular dispersed or colloidal solution of said at least one modified starch b), ii) grinding the suspended particles, iii) mixing the ground suspension with said sucrose c), and iv) subsequently converting the suspension optionally in the presence of a coating material into a dry powder, where the suspension comprises after process step iii), based on the dry matter of the aqueous suspension, from 1 to 25% by weight of β-carotene, and the ratio of β-carotene a) to sucrose c) is from 1:2 to 1:80 by weight.
Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules · CPC title
Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin · CPC title
Plant extracts, their artificial duplicates or their derivatives · CPC title
Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin · CPC title
carbocyclic · CPC title
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