Reservoir for storing a liquid medicament and method of producing a reservoir

Patent metadata

Field	Value
Publication number	US-11337891-B2
Application number	US-201716346678-A
Country	US
Kind code	B2
Filing date	Nov 21, 2017
Priority date	Nov 23, 2016
Publication date	May 24, 2022
Grant date	May 24, 2022

Abstract

The invention concerns a reservoir (1) for storing a liquid medicament. The reservoir (1) comprises a flexible container (10) which includes one folding layer (12), wherein the folding layer (12) includes a seam (13) which provides for a sealing of the flexible container (1). The reservoir comprises a rigid part (20) which is connected to the flexible container (10) and which includes a support (25) extending into the flexible container (10) and which includes one or more ports (21, 22) providing fluidic access to the flexible container (10). The reservoir comprises a porous hydrophilic membrane (26) which is connected to the support (25) of the rigid part (20). The invention further concerns a method for producing of a reservoir (1). The method comprises: providing a flexible tube (30) and a movable opening device (40) located inside the flexible tube (30), moving (S1) the moveable opening device (40) inside the flexible tube (30) by a distance in a longitudinal direction of the flexible tube (30), providing a rigid part (20), and bonding (S2) the flexible tube (30) to the rigid part (20) and providing a folding layer (12) included in the flexible container (10).

First claim

The invention claimed is:

1. A reservoir for storing a liquid medicament, comprising:
a flexible container comprising a proximal end and a distal end, and further including side walls extending from the distal end and terminating at the proximal end, the side walls defining a proximal end opening, the flexible container comprising a folding layer terminating at the distal end in a seam which provides for a sealing of the flexible container,
a rigid part connected to the side walls and enclosing the proximal end opening of the flexible container, the rigid part including one or more ports;
a support connected to the rigid part and extending into the flexible container, the support including an opening in communication with the one or more ports and providing fluidic access to the interior of the flexible container, and
a porous hydrophilic membrane connected to the support and covering the opening of the support,
the reservoir having a first condition in which the folding layer is folded and a second condition in which the folding layer is unfolded.

2. The reservoir according to claim 1 , wherein the flexible container includes four side walls defining a proximal rectangular end opening, the rigid part being rectangular and being received by and connected to the four side walls, the rigid part enclosing the proximal rectangular end opening, thereby sealing the proximal rectangular end opening.

3. The reservoir according to claim 2 , wherein the flexible container includes a section of a foil tube, the section of the foil tube has a rectangular cross section defining the proximal rectangular end opening of the flexible container.

4. The reservoir according to claim 1 , wherein the flexible container includes a section of a foil tube.

5. The reservoir according to claim 4 , wherein the section of the foil tube has a folded cross section.

6. The reservoir according to claim 1 , wherein the folding layer provides that walls of the flexible container exhibit a curved surface.

7. The reservoir according to claim 1 , wherein the folding layer and the rigid part are arranged on opposite sides of the flexible container.

8. The reservoir according to claim 1 , wherein the flexible container is bonded to the rigid part.

9. The reservoir according to claim 1 , wherein the rigid part includes one or more mounting parts for mounting the reservoir to a medical device.

10. The reservoir according to claim 1 , wherein the rigid part includes one or more pins for mounting the reservoir to a medical device.

11. A method for producing a reservoir comprising:
providing a flexible tube and a movable opening device located inside the flexible tube,
moving the movable opening device inside the flexible tube by a distance in a longitudinal direction of the flexible tube to provide a flexible container,
forming a seam in the flexible tube to provide a sealed distal end of the flexible container,
providing a folding layer in the flexible container adjacent the seam,
removing the movable opening device from the flexible container to provide the flexible container with a proximal end, a distal end, and side walls extending from the distal end to terminate at the proximal end, and the side walls defining a proximal end opening,
providing a rigid part, and
bonding the side walls of the flexible container to the rigid part, thereby enclosing the proximal end opening.

12. The method according to claim 11 , wherein the flexible tube and the rigid part are provided having a rectangular cross section enabling bonding of the flexible tube to the rigid part.

13. The method according to claim 11 , wherein the flexible tube is a part of a foil tube and the forming the seam includes forming the seam and separating the flexible tube from the foil tube.

14. A method for filling a reservoir according to claim 1 , comprising: actuating a fill device connected to the reservoir for filling the reservoir via the one or more ports at least partly with the liquid medicament thereby unfolding the flexible container.

15. A method for delivering a liquid medicament from a reservoir according to claim 1 , comprising: actuating a delivery device connected to the reservoir for at least a partial delivery via the one or more ports of the liquid medicament stored in the reservoir and thereby folding the flexible container during the delivering.

16. A medical pump for an automated administration of a liquid medicament, wherein the medical pump comprises a reservoir according to claim 1 .

Assignees

• Roche Diabetes Care Inc

Inventors

• Leichner Wilhelm
• List Hans

Classifications

• A61M1/602

  Mechanical means for preventing flexible containers from collapsing when vacuum is applied inside, e.g. stents · CPC title

• A61M2205/7527

  liquophilic, hydrophilic · CPC title

• A61M5/148

  flexible, {e.g. independent bags}(A61M5/155 takes precedence) · CPC title

• A61M2209/045

  for filling, e.g. for filling reservoirs · CPC title

• A61M2205/126

  with incorporated membrane filters · CPC title