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Polyoxometalate complexes and uses in managing cancer
US11331297B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11331297-B2 |
| Application number | US-201716345578-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 26, 2017 |
| Priority date | Oct 26, 2016 |
| Publication date | May 17, 2022 |
| Grant date | May 17, 2022 |
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- Title
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Abstract
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The disclosure relates polyoxometalate complexes and uses in the management, treatment, or prevention of cancer. In certain embodiments, the polyoxometalate complexes comprise polydentate oxygen bridging ligands such as those of the following formula: [POM{(OCH2)3CX}2], [M6O13{(OCH2)3CX}2], [V6O13 {(OCH2)3CX}2], salts, or derivatives thereof wherein POM is a polyoxometalate, M is a metal, and X is defined herein. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising polyoxometalate complexes disclosed herein.
First claim
Opening claim text (preview).
The invention claimed is: 1. A method of treating cancer comprising administering an effective amount of [V 6 O 13 {(OCH 2 ) 3 CNH 3 } 2 ], or salts thereof to a subject in need thereof. 2. The method of claim 1 , wherein the subject is diagnosed with cancer. 3. The method of claim 1 , wherein the cancer is leukemia, lymphoma, melanoma, glioblastoma, cervical, ovarian, colon, breast, gastric, lung, skin, ovarian, pancreatic, prostate, head, neck, bladder, and renal cancer. 4. The method of claim 1 , wherein the polyoxometalate complex is administered in combination with a second chemotherapeutic agent. 5. The method of claim 4 , wherein the second chemotherapy agent is a platinum-based antineoplastic, cisplatin, carboplatin, oxaliplatin, nedaplatin, triplatin tetranitrate, phenanthriplatin, picoplatin, satraplatin, or combinations thereof.
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Compounds containing amino and carboxyl groups bound to the same carbon skeleton · CPC title
the layer being formed} of fibres, chips, or particles {, e.g. MDF, HDF, OSB, chipboard, particle board, hardboard · CPC title
Anti-corrosive paints · CPC title
Emulsion paints {including aerosols} · CPC title
macromolecular (C09D7/41-C09D7/48 take precedence) · CPC title
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- What does patent US11331297B2 cover?
- The disclosure relates polyoxometalate complexes and uses in the management, treatment, or prevention of cancer. In certain embodiments, the polyoxometalate complexes comprise polydentate oxygen bridging ligands such as those of the following formula: [POM{(OCH2)3CX}2], [M6O13{(OCH2)3CX}2], [V6O13 {(OCH2)3CX}2], salts, or derivatives thereof wherein POM is a polyoxometalate, M is a metal, and X…
- Who is the assignee on this patent?
- Univ Emory
- What technology area does this patent fall under?
- Primary CPC classification A61K31/28. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue May 17 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).