Probiotic formulations for improving athletic performance

Patent metadata

Field	Value
Publication number	US-11324783-B2
Application number	US-202117395588-A
Country	US
Kind code	B2
Filing date	Aug 6, 2021
Priority date	Apr 11, 2016
Publication date	May 10, 2022
Grant date	May 10, 2022

Abstract

A probiotic formulation is provided including one or more bacteria, bacterial strains or bacterial species of the genus Veillonella, genus Faecalibacterium, genus Phascolarctobacteria, genus Oscillospira, genus Ruminococcus, genus Bacteroides, genus Blautia, family Christensenellaceae, genus Dialister, or phylum cyanobacteria.

First claim

The invention claimed is:

1. A probiotic composition formulated for administration to a human, comprising: at least 10 5 CFU of bacteria of the genus Veillonella , wherein the bacteria are in a dried form.

2. The probiotic composition of claim 1 , wherein the probiotic composition further comprises one or more bacteria selected from the group consisting of: Faecalibacterium, Phascolarctobacteria, Oscillospira, Ruminococcus, Bacteroides, Blautia, Christensenellaceae, Dialister, Lactobacillus , and Cyanobacteria.

3. The probiotic composition of claim 1 , wherein the probiotic composition comprises Veillonella atypica.

4. The probiotic composition of claim 1 , wherein the probiotic composition comprises Veillonella parvula.

5. The probiotic composition of claim 1 , wherein the probiotic composition comprises Veillonella parvula and Veillonella atypica.

6. The probiotic composition of claim 1 , wherein the probiotic composition further comprises one or more Lactobacillus bacteria.

7. The probiotic composition of claim 1 , wherein the Veillonella bacteria are live bacteria.

8. The probiotic composition of claim 1 , wherein the probiotic composition further comprises one or more prebiotics, minerals, vitamins, amino acids, or any combination thereof.

9. The probiotic composition of claim 1 , wherein the probiotic composition further comprises one or more nutraceutical compounds.

10. The probiotic composition of claim 1 , wherein the probiotic composition further comprises one or more flavoring agents.

11. The probiotic composition of claim 1 , wherein the probiotic composition is formulated for oral delivery.

12. The probiotic composition of claim 1 , wherein the probiotic composition is encapsulated.

13. The probiotic composition of claim 1 , wherein the probiotic composition is a dietary supplement.

14. The probiotic composition of claim 1 , wherein the probiotic composition is a dietary supplement formulated to improve athletic training, performance, and/or recovery.

15. The probiotic composition of claim 1 , wherein the probiotic composition is formulated as an ingestible liquid medium, a gel medium, a food stuff, a food product, a beverage, a freeze dried product, a powder, a yogurt, a capsule, a tablet, a pill, a gelatin capsule, a caplet, a chewable formulation, or a dissolvable formulation.

16. The probiotic composition of claim 1 , wherein the probiotic composition is formulated as a food product or food stuff.

17. The probiotic composition of claim 1 , wherein the probiotic composition is formulated as a food product or food stuff, which further comprises prebiotics, minerals, vitamins, amino acids, proteins, or any combination thereof.

18. The probiotic composition of claim 1 , wherein the probiotic composition is formulated as a powder food stuff.

19. The probiotic composition of claim 1 , wherein the probiotic composition is formulated as a powder food stuff, which further comprises prebiotics, minerals, vitamins, amino acids, proteins, or any combination thereof.

20. The probiotic composition of claim 1 , wherein the probiotic composition is formulated as a yogurt.

21. The probiotic composition of claim 1 , wherein the probiotic composition is formulated as a yogurt and the yogurt is a yogurt drink or a yogurt-based beverage.

22. The probiotic composition of claim 1 , wherein the probiotic composition is formulated as a beverage.

23. The probiotic composition of claim 1 , wherein the probiotic composition is formulated as a beverage, which further comprises one or more prebiotics, minerals, vitamins, amino acids, proteins, or any combination thereof.

24. The probiotic composition of claim 1 , wherein administration of the probiotic composition to a human increases the population of Veillonella bacteria within the human.

25. The probiotic composition of claim 1 , wherein administration of the probiotic composition to a human increases or maintains training endurance or performance endurance of the human during physical exercise.

26. The probiotic composition of claim 1 , wherein administration of the probiotic composition to a human reduces muscle fatigue of the human during or following physical exercise.

27. The probiotic composition of claim 1 , wherein administration of the probiotic composition to a human reduces lactate levels of the human during or following physical exercise.

28. The probiotic composition of claim 1 , wherein administration of the probiotic composition to a human reduces inflammation of the human during or following physical exercise.

29. The probiotic composition of claim 1 , wherein administration of the probiotic composition to a human increases energy metabolism and/or promotes weight loss of the human.

30. A kit, comprising: the probiotic composition of claim 1 and instructions for administration of the probiotic composition to the human.

31. The probiotic composition of claim 1 , wherein the Veillonella bacteria are dead bacteria.

32. The probiotic composition of claim 1 , wherein the Veillonella bacteria are freeze dried Veillonella bacteria, spray dried Veillonella bacteria, or fluidized bed dried Veillonella bacteria.

33. The probiotic composition of claim 32 , wherein the Veillonella bacteria are freeze dried Veillonella bacteria.

Assignees

• Harvard College

Inventors

• Scheiman Jonathan
• Church George M

Classifications

• C12N1/20

  Bacteria; Culture media therefor · CPC title

• A23L33/135

  Bacteria or derivatives thereof, e.g. probiotics · CPC title

• C12Q1/025

  for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics (antimicrobial activity C12Q1/18) · CPC title

• A23C9/123

  using only microorganisms of the genus lactobacteriaceae; Yoghurt (A23C9/13 takes precedence) · CPC title

• A61K35/748

  Cyanobacteria, i.e. blue-green bacteria or blue-green algae, e.g. spirulina (algae, microalgae or microphytes A61K36/02) · CPC title