Devices, systems, and methods for the treatment of vascular defects

Patent metadata

Field	Value
Publication number	US-11324513-B2
Application number	US-201916718171-A
Country	US
Kind code	B2
Filing date	Dec 17, 2019
Priority date	Dec 17, 2018
Publication date	May 10, 2022
Grant date	May 10, 2022

Abstract

Devices, systems, and methods for treating vascular defects are disclosed herein. One aspect of the present technology, for example, includes an occlusive device comprising a mesh having a low-profile state for intravascular delivery to the aneurysm and a deployed state, the mesh comprising a first end portion, a second end portion, and a length extending between the first and second end portions, and a first lateral edge, a second lateral edge, and a width extending between the first and second lateral edges. The mesh may have a predetermined shape in the deployed state in which (a) the mesh is curved along its width, (b) the mesh is curved along its length, and (c) the mesh has an undulating contour across at least a portion of one or both of its length or its width. The mesh is configured to be positioned within the aneurysm in the deployed state such that the mesh extends over the neck of the aneurysm.

First claim

We claim:

1. An assembly for forming an occlusive mesh configured to treat a cerebral aneurysm, the assembly comprising:
a first member having a first surface bound between opposing first longitudinal ends and opposing first side edges, the first surface having a first length between the first longitudinal ends and a first width between the first side edges, wherein the first surface is curved along the first length and curved along the first width, and wherein the first surface has a first convex region and a first concave region; and
a second member having a second surface bound between opposing second longitudinal ends and opposing second side edges, the second surface having a second length between the second longitudinal ends and a second width between the second side edges, wherein the second surface is curved along the second length and curved along the second width, and wherein the second surface has a second convex region complementary to the first concave region and a second concave region complementary to the first convex region, and
wherein the assembly is configured to receive a mesh between the first and second surfaces.

2. The assembly of claim 1 , wherein the first concave region is surrounded by the first convex region.

3. The assembly of claim 1 , wherein the second convex region is surrounded by the second concave region.

4. The assembly of claim 1 , wherein:
the first concave region is surrounded by the first convex region, and
the second convex region is surrounded by the second concave region.

5. The assembly of claim 1 , wherein the mesh is a flattened tubular braid.

6. The assembly of claim 1 , wherein the first convex region has a radius of curvature that increases continuously along the first length.

7. The assembly of claim 1 , wherein the second concave region has a radius of curvature that increases continuously along the second length.

8. The assembly of claim 1 , wherein a radius of curvature of the first convex region is greater than a radius of curvature of the first concave region.

9. The assembly of claim 1 , wherein a radius of curvature of the second convex region is less than a radius of curvature of the second concave region.

10. The assembly of claim 1 , wherein the assembly is configured to withstand the application of heat at a temperature sufficient to shape set the mesh while the mesh is between the first and second surfaces.

11. The assembly of claim 1 , wherein the first concave region is a divot.

12. The assembly of claim 11 , wherein the divot extends laterally across at least a portion of the first width.

13. The assembly of claim 11 , wherein the divot extends lengthwise across at least a portion of the first surface.

14. The assembly of claim 1 , wherein the side edges of the first surface are generally parallel to one another.

15. The assembly of claim 1 , wherein the side edges of the second surface are generally parallel to one another.

16. The assembly of claim 1 , further comprising a groove in the first surface, wherein the groove extends diagonally relative to the first side edges.

17. The assembly of claim 16 , wherein the groove is a first groove disposed at one of the first longitudinal ends and the first surface further comprises a second groove disposed at the other of the first longitudinal ends.

18. The assembly of claim 1 , wherein the first concave region is a first longitudinal concave region that extends along at least a portion of the first length and the first surface further includes a first lateral concave region that extends along at least a portion of the first width.

19. The assembly of claim 18 , wherein the first longitudinal concave region and the second longitudinal concave region intersect one another.

20. The assembly of claim 18 , wherein the first longitudinal concave region and the second longitudinal concave region are spaced apart from one another.

21. The assembly of claim 18 , wherein:
the first longitudinal concave region has a first average radius of curvature, the first lateral concave region has a second average radius of curvature, and the first convex region has a third average radius of curvature, and
each of the first and second average radii of curvature are less than the third average radius of curvature.

22. A method for making an occlusive device configured to treat an aneurysm, the method comprising:
positioning a mesh between first and second members of a forming assembly such that the mesh conforms to first and second surfaces of the first and second members, respectively, wherein:
the first surface is bound between opposing first longitudinal ends and opposing first side edges, the first surface having a first length between the first longitudinal ends and a first width between the first side edges, wherein the first surface is curved along the first length and curved along the first width, and wherein the first surface has a first convex region and a first concave region; and
the second surface bound between opposing second longitudinal ends and opposing second side edges, the second surface having a second length between the second longitudinal ends and a second width between the second side edges, wherein the second surface is curved along the second length and curved along the second width, and wherein the second surface has a second convex region complementary to the first concave region and a second concave region complementary to the first convex region, and

applying heat to the assembly forming assembly and the mesh while the mesh is held between the first and second members.

23. The method of claim 22 , wherein the mesh is a generally flat ribbon and the method further comprises forming the generally flat ribbon, wherein forming the generally flat ribbon comprises flattening a tubular mesh such that opposing portions of a sidewall of the mesh are urged towards one another.

24. The method of claim 22 , further comprising compressing the mesh between the first and second members.

25. The method of claim 22 , wherein the first concave region is surrounded by the first convex region.

26. The method of claim 22 , wherein the second convex region is surrounded by the second concave region.

27. The method of claim 22 , wherein:
the first concave region is surrounded by the first convex region, and
the second convex region is surrounded by the second concave region.

28. The method of claim 22 , wherein the mesh is a flattened tubular braid.

29. The method of claim 22 , wherein the first convex region has a radius of curvature that increases continuously along the first length.

30. The method of claim 22 , wherein the second concave region has a radius of curvature that increases continuously along the second length.

31. The method of claim 22 , wherein a radius of curvature of the first convex region is greater than a radius of curvature of the first concave region.

32. The method of claim 22 , wherein a radius of curvature of the second convex region is less than a radius of curvature of the second concave region.

33. The method of claim 22 , wherein the assembly is configured to withstand the application of heat at a temperature sufficient to shape set the mesh while the mesh is between the first and second surfaces.

34

Assignees

• Covidien Lp

Inventors

• Hamel Gregory
• Quinn Patrick
• Rosqueta Arturo
• Sosnowski Stephen
• Andrews Christopher
• Dang Hieu
• Nguyen Dinh
• Pecor Robert
• Dinh Minh Q
• Tatavoosian Ahramahzd

Classifications

• A61B17/12172

  having a pre-set deployed three-dimensional shape (methods of manufacturing A61B2017/00526) · CPC title

• A61B2017/00526

  Methods of manufacturing · CPC title

• A61B17/1214

  Coils or wires · CPC title

• A61B2017/00867

  shape memory effect · CPC title

• A61B17/12118

  for positioning in conjunction with a stent · CPC title