Disposable interconnected pump cassettes having first and second pump chambers with valved inlet and outlet connections

Patent metadata

Field	Value
Publication number	US-11319944-B2
Application number	US-201815966877-A
Country	US
Kind code	B2
Filing date	Apr 30, 2018
Priority date	Oct 30, 2003
Publication date	May 3, 2022
Grant date	May 3, 2022

Abstract

A system and method for pumping fluid using a set of interconnected pump cassettes is disclosed. Each of the pump cassettes can receive a first solution in a first pumping chamber and each of the pump cassettes can receive separate second solutions in respective second pumping chambers, so that the first solution can be mixed with the separate second solutions, each said mixture capable of being placed in separate containers. The system includes a control assembly for operating each pump cassette, each pump cassette having a flexible membrane to pump fluid into and out of the pumping chambers, and each pump cassette configured for mating with a base unit that provides positive or negative pneumatic pressure to the flexible membrane.

First claim

What is claimed is:

1. A disposable set of n interconnected pump cassettes comprising:
a first infusion line to the set connected to a distribution line of the set that has n branches, each branch connected to a respective first inlet of each of the n pump cassettes;
n second infusion lines to the set, each one of the n second infusion lines configured to connect one of n separate solution sources to a respective one of n second inlets of the n pump cassettes;
each one of the n pump cassettes comprising a first and a second pumping chamber, wherein for each pump cassette of the n pump cassettes:
wherein the first inlet of each pump cassette connects via a single valve only to the first pumping chamber, and the second pumping chamber has a valved connection to the second inlet of each of the n pump cassettes, an outlet of the first pumping chamber has a valved connection to the second pumping chamber, and an outlet of the second pumping chamber has a valved connection to an outlet of each of the n pump cassettes; each one of the outlets of the n pump cassettes is connected to a respective one of n containers via a flexible line, each container configured to receive a mixture of fluid from the first inlet and the second inlet of a pump cassette to which said container is connected.

2. The disposable set of claim 1 , wherein each one of said n pump cassettes includes a vent in valved connection with the first or second pumping chamber.

3. The disposable set of claim 2 , wherein each said pumping chamber comprises a flexible membrane configured to pump fluid in and out of the pumping chamber, and configured to mate with a base unit that provides positive or negative pneumatic actuation pressure to the flexible membrane.

4. The disposable set of claim 2 , wherein each of the n second infusion lines is configured to connect to a container holding a mixture of red blood cells.

5. The disposable set of claim 2 , wherein the first infusion line is configured for connection to a container of incubation fluid for mixing with each of the n solution sources.

6. The disposable set of claim 1 , wherein each said pumping chamber comprises a flexible membrane configured to pump fluid in and out of the pumping chamber, and configured to mate with a base unit that provides positive or negative pneumatic actuation pressure to the flexible membrane.

7. The disposable set of claim 1 , wherein each of the n second infusion lines is configured to connect to a container holding a mixture of red blood cells.

8. The disposable set of claim 7 , wherein the first infusion line is configured for connection to a container of incubation fluid for mixing with each of the n solution sources.

9. The disposable set of claim 1 , wherein the first infusion line is configured for connection to a container of incubation fluid for mixing with each of the n solution sources.

10. The disposable set of claim 1 , wherein for each pump cassette of the n pump cassettes, the outlet of the first pumping chamber has a valved connection to a flowpath in the pump cassette, the flowpath having a valved connection to an inlet or the outlet of the second pumping chamber.

11. A disposable set of n interconnected pump cassettes comprising:
a first infusion line to the set connected to a distribution line of the set that has n branches, each branch connected to a respective first inlet of each of the n pump cassettes;
n second infusion lines to the set, each one of the n second infusion lines configured to connect one of n separate solution sources to a respective one of n second inlets of the n pump cassettes;
each one of the n pump cassettes comprising a first and a second pumping chamber, wherein for each pump cassette of the n pump cassettes:
wherein the first inlet of each cassette connects via a single valve only to the first pumping chamber, and the second pumping chamber has a valved connection to the second inlet of each of the n pump cassettes, an outlet of the first pumping chamber has a valved connection to the second pumping chamber, and an outlet of the second pumping chamber has a valved connection to an outlet of each of the n pump cassettes; each one of the outlets of the n pump cassettes is connected to a respective one of n containers via a flexible line, each container configured to receive a mixture of fluid from the first inlet and the second inlet of a pump cassette to which said container is connected; and
wherein each said pumping chamber comprises a flexible membrane configured to pump fluid in and out of the pumping chamber, and configured to mate with a base unit that provides positive or negative pneumatic actuation pressure to the flexible membrane.

12. The disposable set of claim 11 , wherein each one of said n pump cassettes includes a vent in valved connection with the first or second pumping chamber.

13. The disposable set of claim 11 , wherein each of the n second infusion lines is configured to connect to a container holding a mixture of red blood cells.

14. The disposable set of claim 13 , wherein the first infusion line is configured for connection to a container of incubation fluid for mixing with each of the n second solution sources.

15. The disposable set of claim 11 , wherein the first infusion line is configured for connection to a container of incubation fluid for mixing with each of the n solution sources.

16. The disposable set of claim 11 , wherein for each pump cassette of the n pump cassettes, the outlet of the first pumping chamber has a valved connection to a flowpath in the pump cassette, the flowpath having a valved connection to an inlet or the outlet of the second pumping chamber.

Assignees

• Deka Products Lp

Inventors

• Demers Jason A
• Gray Larry B
• Mcgill David W
• Lanigan Richard J

Classifications

• A61L2103/05

  Living organisms or biological materials · CPC title

• A61L2/18

  Liquid substances · CPC title

• B01F33/81

  Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles · CPC title

• Y10T29/53

  Means to assemble or disassemble · CPC title

• B01F35/711

  for feeding a mixture of components, i.e. solids in liquid, solids in a gas stream · CPC title