Composition containing, as active ingredient, green tea extract with increased polysaccharide content

Patent metadata

Field	Value
Publication number	US-11318180-B2
Application number	US-201816765823-A
Country	US
Kind code	B2
Filing date	Oct 24, 2018
Priority date	Nov 20, 2017
Publication date	May 3, 2022
Grant date	May 3, 2022

Abstract

Disclosed in the present application are: a composition containing a green tea extract comprising at least one selected from the group consisting of 7 wt % or more of polysaccharides, less than 20 wt % of catechins, and 10 wt % or more of dietary fibers, relative to a total weight of the green tea extract, the composition having a use for blood glucose control; and a method for preparing the composition. The composition has not only effects of inhibiting activity of glucosidase and amylase but also effects of lowering blood glucose by inhibiting the glucose uptake in small intestinal cells.

First claim

The invention claimed is:

1. A method for regulating blood glucose, the method comprising:
administering an effective amount of a composition comprising a green tea extract comprising 7 wt % or more of a polysaccharide, less than 20 wt % of catechin and 10 wt % or more of a dietary fiber based on the total weight of the green tea extract to a subject in need of blood glucose regulation.

2. The method according to claim 1 , wherein the green tea extract further comprises less than 7 wt % of a monosaccharide and a disaccharide based on the total weight of the green tea extract.

3. The method according to claim 1 , wherein the green tea extract comprises 9 wt % or more of a polysaccharide based on the total weight of the green tea extract.

4. The method according to claim 1 , wherein the green tea extract comprises 13 wt % or more of a dietary fiber based on the total weight of the green tea extract.

5. The method according to claim 1 , wherein the composition lowers blood glucose.

6. The method according to claim 1 , wherein the composition inhibits carbohydrate digestion and glucose uptake in small intestine cells.

7. The method according to claim 6 , wherein the inhibition of carbohydrate digestion is achieved by inhibiting the activity of amylase or glucosidase.

8. The method according to claim 1 , wherein the green tea extract is a hot-water extract obtained by hot-water extracting an extraction residue of an extract obtained by adding an alcohol or an aqueous alcohol solution to green tea as a first solvent.

9. The method according to claim 8 , wherein the green tea extract is an alcohol or aqueous alcohol solution precipitate of the hot-water extract.

10. The method according to claim 1 , wherein the composition is a pharmaceutical composition.

11. The method according to claim 1 , wherein the composition is a food composition.

Assignees

• Amorepacific Corp

Inventors

• Chung Jinoh
• Kim A Young
• Seo Juyeon
• LEE Bumjin
• Kim Jeong-Kee

Classifications

• A23L33/105 Primary

  Plant extracts, their artificial duplicates or their derivatives · CPC title

• A23V2002/00

  Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title

• A61K36/82 Primary

  Theaceae (Tea family), e.g. camellia · CPC title

• A61K2236/333

  using mixed solvents, e.g. 70% EtOH · CPC title

• A23V2200/328

  having effect on glycaemic control and diabetes · CPC title