Piezoelectric ultrasonic microinjection device based on flexible hinge mechanism

Patent metadata

Field	Value
Publication number	US-11312934-B2
Application number	US-201816958729-A
Country	US
Kind code	B2
Filing date	May 22, 2018
Priority date	May 14, 2018
Publication date	Apr 26, 2022
Grant date	Apr 26, 2022

Abstract

The present invention discloses a piezoelectric ultrasonic microinjection device based on a flexible hinge mechanism. The device includes: a cover, a flexible hinge mechanism, a base, a screw cap and an end cap fixedly assembled together, the base being provided with a pump interface; and a micropipette fixedly mounted in the base, the screw cap and the end cap and extending outward, the micropipette being in communication with the pump interface; wherein the flexible hinge mechanism comprises a housing, a piezoelectric ceramic package module encapsulated in the housing, a central shaft fixedly mounted with the piezoelectric ceramic package module and the base, and a vibration output shaft extending from the piezoelectric ceramic package module into the central shaft, a plurality of flexible hinge beams being disposed between the central shaft and the housing.

First claim

The invention claimed is:

1. A piezoelectric ultrasonic microinjection device based on a flexible hinge mechanism, the device comprising:
a cover, a flexible hinge mechanism, a base, a screw cap and an end cap fixedly assembled together, the base being provided with a pump interface; and
a micropipette fixedly mounted in the base, the screw cap and the end cap and extending outward, the micropipette being in communication with the pump interface;
wherein the flexible hinge mechanism comprises a housing, a piezoelectric ceramic package module encapsulated in the housing, a central shaft fixedly mounted with the piezoelectric ceramic package module and the base, and a vibration output shaft extending from the piezoelectric ceramic package module into the central shaft, a plurality of flexible hinge beams being disposed between the central shaft and the housing;
wherein the end cap and the screw cap as well as the screw cap and the base are respectively fixedly mounted to each other through a thread;
wherein the base comprises a bent section fixedly mounted to the screw cap, and a horizontal section fixedly mounted with the flexible hinge mechanism, the bent section and the horizontal section being respectively fixedly mounted to the screw cap and the flexible hinge mechanism through a thread;
wherein an end of the horizontal section is provided with a first flange, and a plurality of first reinforcing ribs is provided between the first flange and the horizontal section; and
wherein the central shaft of the flexible hinge mechanism is provided with a second flange, and a plurality of second reinforcing ribs is provided between the second flange and the central shaft.

2. The piezoelectric ultrasonic microinjection device based on a flexible hinge mechanism according to claim 1 , wherein a gasket is disposed between the end cap and the screw cap and/or between the screw cap and the base, and two sides of the gasket are different first and second tapered faces.

3. The piezoelectric ultrasonic microinjection device based on a flexible hinge mechanism according to claim 1 , wherein the end cap comprises an end cap body and an end cap mounting portion, an outer diameter of the end cap body being greater than that of the end cap mounting portion, and an outer side of the end cap mounting portion being provided with a first thread, the first thread being adapted for fixedly mounting the end cap mounting portion to the screw cap.

4. The piezoelectric ultrasonic microinjection device based on a flexible hinge mechanism according to claim 3 , wherein a first cavity and a second cavity are formed in the end cap in a direction from the end cap body toward the end cap mounting portion, the second cavity being tapered.

5. The piezoelectric ultrasonic microinjection device based on a flexible hinge mechanism according to claim 2 , wherein the screw cap comprises a screw cap body and a screw cap mounting portion, an outer diameter of the screw cap body being greater than that of the screw cap mounting portion, an inner side of the screw cap body being provided with a second thread fixedly mounted to the end cap, and an outer side of the screw cap mounting portion being provided with a third thread fixedly mounted to the base.

6. The piezoelectric ultrasonic microinjection device based on a flexible hinge mechanism according to claim 5 , wherein a third cavity, a fourth cavity and a fifth cavity are formed in the screw cap in a direction from the screw cap body to the screw cap mounting portion, the fifth cavity being tapered.

7. The piezoelectric ultrasonic microinjection device based on a flexible hinge mechanism according to claim 1 , wherein an inner side of the bent section is provided with a fourth thread fixedly mounted to the screw cap.

8. The piezoelectric ultrasonic microinjection device based on a flexible hinge mechanism according to claim 1 , wherein a sixth cavity and a seventh cavity are provided in the bent section, and an eighth cavity is provided in the horizontal section, the seventh cavity being tapered, and the sixth cavity being in communication with the pump interface through the seventh cavity and a micro flow channel.

9. The piezoelectric ultrasonic microinjection device based on a flexible hinge mechanism according to claim 1 , wherein an inner side of the horizontal section is provided with a fifth thread, an outer side of an end of the central shaft of the flexible hinge mechanism is provided with a sixth thread, and the base and the flexible hinge mechanism are fixedly mounted through the fifth thread and the sixth thread.

10. The piezoelectric ultrasonic microinjection device based on a flexible hinge mechanism according to claim 1 , wherein the flexible hinge beams are provided with a plurality of V-shaped recesses.

11. The piezoelectric ultrasonic microinjection device based on a flexible hinge mechanism according to claim 1 , wherein the flexible hinge beams are distributed in a circumferential array with an equal angle of 120° centered on the central shaft, and the flexible hinge beams in each direction are distributed in a parallel linear array of equidistant double flexible hinge beams at a certain distance in the axial direction.

12. The piezoelectric ultrasonic microinjection device based on a flexible hinge mechanism according to claim 1 , wherein the central shaft is provided with a mounting hole, and a screw is fixedly mounted in the mounting hole to fix the central shaft and the vibration output shaft.

Assignees

• Univ Soochow

Inventors

• Huang Haibo
• Gao Xiwei
• Chen Liguo
• Zhou Fei
• Guo Hao
• Chang Lingfeng
• Liu Jizhu
• Wang Yangjun
• Sun Lining

Classifications

• C12M33/04

  by injection or suction, e.g. using pipettes, syringes, needles (pipettes in general B01L3/02) · CPC title

• B01L2400/0475

  specific mechanical means and fluid pressure · CPC title

• B01L2300/042

  Caps; Plugs · CPC title

• C12M35/04 Primary

  Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli · CPC title

• C12M23/16

  Microfluidic devices; Capillary tubes (integrated microfluidic structures B01L3/5027; microreactors B01J19/0093) · CPC title