Packaging and devices for mixing medicament substances

Patent metadata

Field	Value
Publication number	US-11311673-B2
Application number	US-201716462038-A
Country	US
Kind code	B2
Filing date	Nov 17, 2017
Priority date	Nov 18, 2016
Publication date	Apr 26, 2022
Grant date	Apr 26, 2022

Abstract

A device ( 200 ) for mixing first and second substances. The device comprises a first container ( 100 ) for storage of the first substance and a second container ( 150 ) received in the first container ( 100 ) and for storage of the second substance. An outlet ( 112 ) is disposed at the distal end of the first container ( 100 ). Valve means ( 180 ) are provided for closing a distal end of the second container ( 150 ) and a proximal end of the first container ( 100 ). A stopper means ( 166 ) closes a proximal end of the second chamber ( 152 ) and is movable with respect to the second container ( 150 ). An operating mechanism drives relative movement between the first and second containers for causing displacement of the second substance into the first chamber ( 102 ) through the valve means ( 180 ) when the outlet ( 112 ) is closed, for mixing the first and second substances in a mixing stroke of the device.

First claim

The invention claimed is:

1. A device for mixing first and second substances in a cartridge comprising a first container having a first chamber for storage of the first substance, an outlet disposed at a distal end of the first chamber, a closure member for closing the outlet, a second container at least partially received in the first container and having a second chamber for storage of the second substance, a valve for closing a distal end of the second chamber and a proximal end of the first chamber, and a stopper for closing a proximal end of the second chamber, the stopper being movable with respect to the second container, the device comprising:
a cartridge holder for receiving the cartridge;
a mixing drive element;
a delivery drive element; and
an operating mechanism comprising a spring for driving movement of the mixing drive element in a distal direction with respect to the cartridge holder upon activation of the operating mechanism, thereby to cause relative movement between the first container and the second container and to displace the second substance into the first chamber through the valve when the outlet is closed to cause mixing of the first and second substances in a mixing stroke of the device;
wherein the second container, in response to actuation of the delivery drive element, moves in a distal direction with respect to the first container when the outlet is open to displace the mixed first and second substances through the outlet in a delivery stroke of the device,
wherein movement of the mixing drive element in the distal direction causes proximal movement of the second container with respect to the cartridge holder, and
wherein the proximal movement of the second container during the mixing stroke of the device causes movement of the delivery drive element from an initial position into an operating position disposed proximally with respect to the initial position.

2. The device according to claim 1 , wherein the mixing drive element is arranged to displace the stopper of the cartridge in a distal direction with respect to the second container during the mixing stroke.

3. The device according to claim 2 , wherein the mixing drive element comprises a plunger.

4. The device according to claim 1 , wherein the delivery drive element comprises a button.

5. The device according to claim 1 , wherein the delivery drive element is attachable to the second container of the cartridge.

6. The device according to claim 5 , further comprising a clamp arrangement for securing the delivery drive element to the second container.

7. The device according to claim 6 , wherein the clamp arrangement is arranged to apply a clamping force to an outer wall of the second container.

Assignees

• Owen Mumford Ltd

Inventors

• Cowe Toby

Classifications

• A61M5/2066

  comprising means for injection of two or more media, e.g. by mixing · CPC title

• A61M5/284 Primary

  comprising means for injection of two or more media, e.g. by mixing · CPC title

• A61J1/2037

  having valve means · CPC title

• A61J1/2089

  Containers or vials which are to be joined to each other in order to mix their contents (combinations of vial and syringe for mixing their contents A61J1/2096) · CPC title

• A61M5/002

  Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics (needle protection, e.g. caps, A61M5/3202; for sharps A61B50/3001) · CPC title