Methods and compositions for treating melanoma
US-2024424002-A1 · Dec 26, 2024 · US
Treatment of GVHD
US11311541B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11311541-B2 |
| Application number | US-201515303420-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 9, 2015 |
| Priority date | Apr 9, 2014 |
| Publication date | Apr 26, 2022 |
| Grant date | Apr 26, 2022 |
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- Title
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- Abstract
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Abstract
Official abstract text for this publication.
The invention relates to treatment of graft versus host disease (GVHD) using compounds that inhibit ROCK2. In preferred aspects, the present invention provides methods for the treatment of GVHD, including chronic GVHD (cGVHD) using compounds having the formulae 1-XXV, as set forth herein.
First claim
Opening claim text (preview).
We claim: 1. A method of treating sclerodermatous chronic graft versus host disease in a subject in need thereof, which comprises administering to the subject an effective amount of a compound of Formula: or pharmaceutically acceptable salt thereof. 2. The method of claim 1 , wherein the compound is administered to the subject with a second agent.
Assignees
Inventors
Classifications
Ortho-condensed systems · CPC title
containing three or more hetero rings · CPC title
having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine (melarsoprol A61K31/555 {; with four nitrogen atoms A61K31/495}) · CPC title
containing three or more hetero rings · CPC title
Two nitrogen atoms · CPC title
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Frequently asked questions
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- What does patent US11311541B2 cover?
- The invention relates to treatment of graft versus host disease (GVHD) using compounds that inhibit ROCK2. In preferred aspects, the present invention provides methods for the treatment of GVHD, including chronic GVHD (cGVHD) using compounds having the formulae 1-XXV, as set forth herein.
- Who is the assignee on this patent?
- Kadmon Corp Llc, Univ Minnesota
- What technology area does this patent fall under?
- Primary CPC classification A61K31/506. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Apr 26 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).