Novel polypeptide and method of producing imp using the same
US-2020377558-A1 · Dec 3, 2020 · US
Polypeptide and method of producing IMP using the same
US11299521B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11299521-B2 |
| Application number | US-201816346041-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 14, 2018 |
| Priority date | Dec 15, 2017 |
| Publication date | Apr 12, 2022 |
| Grant date | Apr 12, 2022 |
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- Title
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Abstract
Official abstract text for this publication.
The present disclosure relates to a novel polypeptide having an activity of exporting 5′-inosine monophosphate, a microorganism comprising the same, a method for preparing 5′-inosine monophosphate using the same, and a method for increasing export of 5′-inosine monophosphate.
First claim
Opening claim text (preview).
The invention claimed is: 1. A protein variant exporting 5′-inosine monophosphate, comprising a polypeptide having at least 95% sequence identity to SEQ ID NO: 1, wherein the 164 th amino acid in the amino acid sequence of SEQ ID NO: 1 is substituted with another amino acid at the corresponding position in the protein variant, wherein the protein variant has 5′-inosine monophosphate exporting activity. 2. The protein variant of claim 1 , wherein the another amino acid is selected from the group consisting of lysine, arginine, asparagine, glycine, threonine, and proline. 3. A polynucleotide encoding the protein variant of claim 1 . 4. A vector comprising the polynucleotide of claim 3 . 5. A microorganism of genus Corynebacterium producing 5′-inosine monophosphate, which comprises the protein variant of claim 1 ; a polynucleotide encoding the protein variant of claim 1 ; or a vector comprising the polynucleotide encoding the protein variant of claim 1 . 6. The microorganism of the genus Corynebacterium of claim 5 , wherein the microorganism of the genus Corynebacterium is Corynebacterium stationis. 7. A method for preparing 5′-inosine monophosphate, comprising culturing the microorganism of the genus Corynebacterium of claim 5 in a medium; and recovering 5′-inosine monophosphate from the microorganism or the medium. 8. The method of claim 7 , wherein the microorganism of the genus Corynebacterium is Corynebacterium stationis.
Assignees
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Classifications
for Corynebacterium; for Brevibacterium · CPC title
Corynebacterium · CPC title
- C07K14/34Primary
from Corynebacterium (G) · CPC title
Bacteria; Culture media therefor · CPC title
having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide · CPC title
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- What does patent US11299521B2 cover?
- The present disclosure relates to a novel polypeptide having an activity of exporting 5′-inosine monophosphate, a microorganism comprising the same, a method for preparing 5′-inosine monophosphate using the same, and a method for increasing export of 5′-inosine monophosphate.
- Who is the assignee on this patent?
- Cj Cheiljedang Corp
- What technology area does this patent fall under?
- Primary CPC classification C07K14/34. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 6 related publications on this page (citations in our corpus or others sharing the same primary CPC).