KRAS G12C inhibitors and methods of using the same
US-10519146-B2 · Dec 31, 2019 · US
Synthesis of key intermediate of KRAS G12C inhibitor compound
US11299491B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11299491-B2 |
| Application number | US-201916685841-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 15, 2019 |
| Priority date | Nov 16, 2018 |
| Publication date | Apr 12, 2022 |
| Grant date | Apr 12, 2022 |
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- Title
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- Abstract
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- Assignees and inventors
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- Key dates
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- First independent claim
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- CPC / IPC classifications
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Abstract
Official abstract text for this publication.
The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure useful for the synthesis of compounds that target KRAS G12C mutations, such as
First claim
Opening claim text (preview).
What is claimed is: 1. A compound, wherein the compound is:
Assignees
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Classifications
Separation of optically-active compounds · CPC title
Optical isomers · CPC title
with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms · CPC title
Benzoic acid esters · CPC title
by change in the physical state, e.g. crystallisation · CPC title
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Frequently asked questions
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- What does patent US11299491B2 cover?
- The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure useful for the synthesis of compounds that target KRAS G12C mutations, such as
- Who is the assignee on this patent?
- Amgen Inc
- What technology area does this patent fall under?
- Primary CPC classification C07D471/04. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 12 related publications on this page (citations in our corpus or others sharing the same primary CPC).