Method and device for processing tissues and cells
US-2018361382-A1 · Dec 20, 2018 · US
US11298707B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11298707-B2 |
| Application number | US-201916253567-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 22, 2019 |
| Priority date | Jan 23, 2018 |
| Publication date | Apr 12, 2022 |
| Grant date | Apr 12, 2022 |
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A method and a device for monitoring the rotational speed of an element are disclosed. The element may be part of a centrifuge, e.g. a motor, drive shaft, or rotor of a laboratory centrifuge. The rotational speed of the element is not determined directly, but rather clock cycles are counted while the element rotates by a predetermined rotational angle. Exceeding a predetermined rotational speed is determined by comparing a number of counted cycles with a predetermined value. The method and device can be implemented in hardware without requiring a microcontroller with corresponding software, thereby eliminating a need to software certification.
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What is claimed is: 1. A method for monitoring a rotational speed of an element and detecting when the rotational speed of the element exceeds a predetermined rotational speed, comprising: generating a clock signal with a defined frequency; counting a number of cycles of the clock signal within a period of time during which the element rotates by a predetermined fraction or multiple of one revolution; comparing the counted number of cycles with a predetermined counter value; determining that the rotational speed of the element exceeds the predetermined rotational speed when the counted number of cycles falls below the predetermined counter value; reducing the rotational speed of the element when the counted number of cycles falls below the predetermined counter value; storing, in a results memory, that the rotational speed of the element has exceeded the predetermined rotational speed; and deleting the results memory by a control signal indicating that the element has come to a standstill or has reached a peripheral speed of less than 3 m/s. 2. The method according to claim 1 , wherein the predetermined counter value is proportional to a product of the time required for the element to complete one revolution at the predetermined rotational speed and the defined frequency of the clock signal, rounded to a natural number. 3. The method according to claim 1 , wherein rotation of the element is sensed electromagnetically by at least one magnet interacting with a magnetic sensor. 4. The method according to claim 1 , wherein the element is part of a laboratory centrifuge and wherein the predetermined rotational speed is adapted for the element. 5. The method according to claim 4 , wherein the predetermined rotational speed is encoded on and read out from the element, and wherein i) encoding of the predetermined rotational speed is effected by one or more magnets and reading out is effected by a Hall sensor or ii) encoding is effected by an RFID transponder and reading out is effected by an RFID receiver. 6. The method according to claim 1 , wherein the rotational speed of the element is reduced to a standstill when the counted number of cycles falls below the predetermined counter value. 7. A device for monitoring a rotational speed of an element and detecting when the rotational speed of the element exceeds a predetermined rotational speed, comprising: a clock generator which generates a clock signal with a defined frequency, a revolution detector which senses rotation of the element by a predetermined fraction or multiple of one revolution; a binary counter adapted to count a number of cycles of the clock signal during which the element rotates by the predetermined fraction or multiple of one revolution; a comparator adapted to compare the counted number of cycles with a predetermined counting value; and a results memory configured to store that the rotational speed of the element has exceeded the predetermined rotational speed, the results memory having an input for a control signal indicating that the element has come to a standstill or has reached a peripheral speed of less than 3 m/s, wherein the control signal causes the results memory to be deleted, wherein exceeding of the predetermined rotational speed is detected by the counted number of cycles falling below the predetermined counting value, and wherein the device reduces the rotational speed of the element when the counted number of cycles falls below the predetermined counting value. 8. The device according to claim 7 , wherein the clock generator is a quartz-stabilized clock generator and/or wherein a controller for controlling the rotational speed of the element is adapted to reduce the rotational speed of the element if an exceeding of the predetermined rotational speed is detected. 9. The device according to claim 7 , wherein the revolution detector is operatively connected to a D flip-flop and thereby adapted to react only to a rising or falling signal edge. 10. The device according to claim 7 , wherein the binary counter is adapted to count the number of cycles of the clock signal during which the element rotates by the predetermined fraction or multiple of one revolution and not to count during a subsequent time period during which the element rotates by the predetermined fraction or multiple of one revolution. 11. The device according to claim 7 , wherein the binary counter is an 8-bit binary counter. 12. The device according to claim 7 , wherein the comparator is as an 8-bit comparator. 13. The device according to claim 7 , wherein the binary counter comprises an overflow memory. 14. The device according to claim 13 , wherein a sequence controller is provided which resets at least one of the binary counter, the comparator, and the overflow memory. 15. The method as in claim 1 , wherein the element is a centrifuge rotor with a centrifuge, the method further comprising: deleting the results memory in response to a signal indicating that a cover of the centrifuge is open. 16. The method as in claim 1 , further comprising: transmitting an output signal from the results memory into a motor control. 17. The device according to claim 7 , wherein an output signal from the results memory is transmitted into a motor control, and wherein the motor control is configured to reduce the rotational speed of the element to a standstill when the output signal is high. 18. A method for preventing excessive rotational speed of a rotor within a centrifuge, comprising: generating a clock signal with a defined frequency; counting a number of cycles of the clock signal within a period of time during which the rotor rotates by a predetermined fraction or multiple of one revolution; comparing the counted number of cycles with a predetermined counter value; determining that the rotational speed of the rotor exceeds the predetermined rotational speed when the counted number of cycles falls below the predetermined counter value; storing, in a results memory, that the rotational speed of the rotor has exceeded the predetermined rotational speed; transmitting a control signal from the results memory to a motor controller while the results memory stores that the rotor has exceeded the predetermined rotational speed; reducing the speed of the rotor to a standstill in response to the control signal; and deleting the results memory by a control signal indicating that a cover of the centrifuge has been opened.
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