Nanoparticle-lipid composite carriers and uses thereof
US-2020170946-A1 · Jun 4, 2020 · US
Magnetic nanocomposite compositions
US11298430B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11298430-B2 |
| Application number | US-201916587973-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 30, 2019 |
| Priority date | Oct 1, 2018 |
| Publication date | Apr 12, 2022 |
| Grant date | Apr 12, 2022 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
Superparamagnetic nanocomposites are provided. In an embodiment, a superparamagnetic nanocomposite comprises a superparamagnetic core comprising a first, soft superparamagnetic ferrite and a superparamagnetic shell comprising a second, soft superparamagnetic ferrite, the shell formed over the core, wherein the first and second soft superparamagnetic ferrites are different compounds and have different magnetocrystalline anisotropies.
First claim
Opening claim text (preview).
What is claimed is: 1. A superparamagnetic nanocomposite comprising a superparamagnetic core comprising a first, soft superparamagnetic ferrite and a superparamagnetic shell comprising a second, soft superparamagnetic ferrite, the shell formed over the core, wherein the first and second soft superparamagnetic ferrites are different compounds and have different magnetocrystalline anisotropies, wherein the first soft superparamagnetic ferrite is MnFe 2 O 4 and the second soft superparamagnetic ferrite is Zn 0.2 Mn 0.8 Fe 2 O 4 or the first soft superparamagnetic ferrite is Zn 0.2 Mn 0.8 Fe 2 O 4 and the second soft superparamagnetic ferrite is MnFe 2 O 4 . 2. The superparamagnetic nanocomposite of claim 1 , wherein a sample of nanoparticles composed of the first, soft superparamagnetic ferrite and having an average diameter of 12 nm provides a magnetization-field loop exhibiting no hysteresis at room temperature and a single-peaked zero-field cooling curve having a blocking temperature of less than room temperature. 3. The superparamagnetic nanocomposite of claim 1 , wherein the nanocomposite is characterized by a specific absorption rate of at least 300 W/g. 4. The superparamagnetic nanocomposite of claim 1 , wherein the nanocomposite is characterized by a specific absorption rate of at least 600 W/g. 5. The superparamagnetic nanocomposite of claim 1 , wherein the first soft superparamagnetic ferrite is MnFe 2 O 4 and the second soft superparamagnetic ferrite is Zn 0.2 Mn 0.8 Fe 2 O 4 . 6. The superparamagnetic nanocomposite of claim 1 , wherein the first soft superparamagnetic ferrite is Zn 0.2 Mn 0.8 Fe 2 O 4 and the second soft superparamagnetic ferrite is MnFe 2 O 4 . 7. The superparamagnetic nanocomposite of claim 1 , wherein the nanocomposite is free of Co, Pt, Nd, and Sm. 8. The superparamagnetic nanocomposite of claim 1 , wherein the nanocomposite is a nanoparticle. 9. A composition comprising the superparamagnetic nanocomposite of claim 1 and a carrier. 10. A method comprising delivering the superparamagnetic nanocomposite of claim 1 to a patient and exposing the nanocomposite to a magnetic field. 11. A method comprising delivering the superparamagnetic nanocomposite of claim 1 to a patient and exposing the nanocomposite to an external radio frequency field.
Assignees
Inventors
Classifications
Zinc oxides, zincates, cadmium oxides, cadmiates, mercury oxides, mercurates or oxide forming salts thereof · CPC title
nanometer sized, i.e. below 100 nm · CPC title
Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use (preparation of fullerenes in general C01B32/15) · CPC title
- A61K49/1827Primary
having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle · CPC title
- C04B35/62826Primary
Iron group metal oxides · CPC title
Patent family
Related publications grouped by family.
External sources
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US11298430B2 cover?
- Superparamagnetic nanocomposites are provided. In an embodiment, a superparamagnetic nanocomposite comprises a superparamagnetic core comprising a first, soft superparamagnetic ferrite and a superparamagnetic shell comprising a second, soft superparamagnetic ferrite, the shell formed over the core, wherein the first and second soft superparamagnetic ferrites are different compounds and have dif…
- Who is the assignee on this patent?
- Univ Northwestern
- What technology area does this patent fall under?
- Primary CPC classification A61K49/1827. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Apr 12 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 7 related publications on this page (citations in our corpus or others sharing the same primary CPC).