Ophthalmic device for drug delivery

Patent metadata

Field	Value
Publication number	US-11298262-B2
Application number	US-201916516356-A
Country	US
Kind code	B2
Filing date	Jul 19, 2019
Priority date	Jul 23, 2018
Publication date	Apr 12, 2022
Grant date	Apr 12, 2022

Abstract

An ophthalmic implant for drug delivery. The implant includes a primary intracapsular device coupled to a secondary device, wherein, when implanted in a patient's eye, the primary intracapsular device is held in place by the patient's capsular bag and the secondary device is held in place by the primary intracapsular device. The implant may be inserted in the eye by injecting the primary intracapsular device into the eye either before or after attaching the secondary device to the primary intracapsular device, and subsequently positioning the joined secondary device and primary intracapsular device with the primary intracapsular device held in place by the patient's capsular bag and the secondary device held in place by the primary intracapsular device. The secondary device may be designed to hold a tertiary device that can be implanted and attached at the time of surgery or anytime postoperatively.

First claim

What is claimed is:

1. An ophthalmic implant comprising:
a multi-part IOL assembly comprising a primary device ( 23 ) comprising an IOL ( 22 ) and a secondary device comprising a first drug delivery device ( 30 );

wherein:
said IOL ( 22 ) comprising a lens ( 24 ), a tab ( 26 ), and a haptic ( 28 );
said tab ( 26 ) extending from the IOL ( 22 ), and said tab ( 26 ) configured to engage the first drug delivery device ( 30 );
said haptic ( 28 ) extending radially outwardly from the lens ( 24 ), such that said haptic ( 28 ) is configured to hold the IOL ( 22 ) in place within a capsular bag of a patient's eye;
said first drug delivery device ( 30 ) comprises a ring configured for a mechanical fit on the tab ( 26 ); and
in an assembled configuration, the first drug delivery device ( 30 ) is engaged in said mechanical fit with the tab ( 26 ) to secure the first drug delivery device ( 30 ) to the IOL ( 22 ) such that the tab ( 26 ) extends from the IOL ( 22 ) through a hole in the first drug delivery device ( 30 ) to establish said mechanical fit on the tab ( 26 ).

2. The ophthalmic implant of claim 1 , wherein:
the first drug delivery device ( 30 ) comprises a drug pad integrated into the first drug delivery device ( 30 ).

3. The ophthalmic implant of claim 1 , wherein:
the first drug delivery device ( 30 ) is further configured to comprise a drug pad.

4. The ophthalmic implant of claim 1 , wherein:
the first drug delivery device ( 30 ) further comprises a refillable reservoir.

5. The ophthalmic implant of claim 1 , further comprising:
a second drug delivery device ( 39 ) configured for attachment to the first drug delivery device ( 30 ).

6. The ophthalmic implant of claim 1 , wherein:
the haptic ( 28 ) extending radially outwardly from the lens ( 24 ) extends outwardly in a plane of the lens.

7. The ophthalmic implant of claim 1 , wherein:
the IOL ( 22 ) has an anterior side ( 24 ) and is configured for placement into the eye of a patient with said anterior side ( 24 ) disposed anteriorly in the eye of the patient; and
the tab ( 26 ) extends from the anterior side ( 24 ) of the IOL ( 22 ).

Assignees

• Univ Colorado Regents
• Spyglass Pharma Inc

Inventors

• Kahook Malik Y
• Sussman Glenn
• Cable Ii Craig Alan

Classifications

• A61F2/1613 Primary

  having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus · CPC title

• A61F2220/0025

  Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements · CPC title

• A61F2002/1683

  having filiform haptics · CPC title

• A61F2/16

  Intraocular lenses · CPC title

• A61F2/15

  Implant having one or more holes, e.g. for nutrient transport, for facilitating handling · CPC title