Ceramic bodies having antimicrobial properties and methods of making the same

Patent metadata

Field	Value
Publication number	US-11298213-B2
Application number	US-201816167950-A
Country	US
Kind code	B2
Filing date	Oct 23, 2018
Priority date	Oct 23, 2017
Publication date	Apr 12, 2022
Grant date	Apr 12, 2022

Abstract

A method for making a ceramic body comprised of a ceramic material having an inhibitory effect on bacterial growth is provided. A dental prosthesis may be made of a ceramic material that comprises a molybdenum-containing component on a portion of the prosthesis that contacts the gingival surface of a patient. In one method, a porous zirconia ceramic structure is shaped in the form of a dental prosthesis, and then infiltrated with a molybdenum-containing composition, before sintering to densify the ceramic structure.

First claim

I claim:

1. A method of making a sintered ceramic dental prosthesis for restoring dentition of a patient that inhibits bacterial growth, comprising
a. obtaining a porous ceramic body comprising a shape of a dental prosthesis,
b. obtaining a liquid molybdenum-containing composition comprising from 0.015 wt % to 5 wt % of a molybdenum-containing component, based on the weight of the molybdenum-containing composition,
c. infiltrating the liquid molybdenum-containing composition into a first portion of the porous ceramic body that corresponds to a portion of the sintered ceramic body that contacts a gingival surface of the patient, and
d. sintering the infiltrated porous zirconia ceramic to form the sintered ceramic dental prosthesis.

2. The method of claim 1 , wherein the liquid molybdenum-containing composition is an aqueous solution.

3. The method of claim 1 , wherein the liquid molybdenum-containing composition comprises a resin.

4. The method of claim 1 , wherein the molybdenum-containing component comprises a molybdenum-containing salt.

5. The method of claim 1 , wherein the molybdenum-containing component comprises molybdenum (V) chloride (MoCl 5 ).

6. The method of claim 1 , wherein the liquid molybdenum-containing composition comprises from 0.015 wt % to 3 wt % of the molybdenum-containing component, based on the weight of the molybdenum-containing composition.

7. The method of claim 1 , wherein the liquid molybdenum-containing composition comprising 0.015 wt % to less than 0.1 wt % of the molybdenum-containing component, based on the weight of the molybdenum-containing composition.

8. The method of claim 1 , wherein the dental prosthesis is an implant, and the porous zirconia ceramic body is fully infiltrated with the liquid molybdenum-containing composition.

9. The method of claim 1 , wherein the dental prosthesis is a crown, and the first portion corresponds to an intaglio surface or a margin of the sintered ceramic dental prosthesis.

10. The method of claim 1 , wherein the dental prosthesis is a crown, and the first portion corresponds to a cervical third region of the sintered ceramic dental prosthesis.

11. The method of claim 1 , wherein the dental prosthesis is an implant abutment and the first portion corresponds to a subgingival portion when the sintered ceramic dental restoration is installed in the mouth of a user.

12. The method of claim 1 , wherein the porous ceramic body comprises an yttria-stabilized zirconia.

13. The method of claim 1 , wherein the sintering step is performed at a sintering temperature greater than 800° C.

14. The method of claim 1 , wherein the porous body comprises a second portion that is not infiltrated with the liquid molybdenum-containing composition, and the second portion corresponds to a vestibular surface of an incisal region of the sintered dental restoration.

Assignees

• Glidewell James R Dental Ceramics Inc

Inventors

• Kim Jae Won

Classifications

• A61K6/824

  comprising transition metal oxides · CPC title

• A61L27/427

  of other specific inorganic materials not covered by A61L27/422 or A61L27/425 · CPC title

• A61K6/818

  comprising zirconium oxide · CPC title

• A61L2430/12

  for dental implants or prostheses · CPC title

• A61C8/008

  Healing caps or the like · CPC title