Ultrasonic diagnostic apparatus and image processing apparatus

Patent metadata

Field	Value
Publication number	US-11298109-B2
Application number	US-201514850807-A
Country	US
Kind code	B2
Filing date	Sep 10, 2015
Priority date	Mar 11, 2013
Publication date	Apr 12, 2022
Grant date	Apr 12, 2022

Abstract

An ultrasonic diagnostic apparatus according to an embodiment includes a candidate-position extracting circuitry and a position setting circuitry. The candidate-position extracting circuitry extracts a first position through comparison of a fundamental wave component between a plurality pieces of image data collected by performing ultrasonic scanning on a subject injected with a contrast agent. The candidate-position extracting circuitry also extracts a second position through comparison of a harmonic component between the pieces of image data. The position setting circuitry sets the first position or the second position as a position of a region of interest where predetermined analysis is performed in at least one image data of the pieces of image data.

First claim

What is claimed is:

1. An ultrasonic diagnostic apparatus comprising:
processing circuitry configured to
control a probe to perform ultrasonic scanning on a subject injected with contrast agent to generate a plurality of pieces of reflected wave data in time series,
generate, in accordance with the plurality of pieces of reflected wave data in time series, a plurality of pieces of fundamental wave data in time series in which tissue in the subject functions as a reflection source and a plurality of pieces of harmonic data in time series in which microbubbles included in the contrast agent function as a reflection source,
generate a plurality of fundamental images based on the plurality of pieces of fundamental wave data in time series and a plurality of harmonic images based on the plurality of pieces of harmonic data in time series,
set, in accordance with a position of a first region of interest in a fundamental image of a first time phase among the plurality of fundamental images, a plurality of sub regions in a fundamental image of a second time phase among the plurality of fundamental images,
compare the first region of interest in the fundamental image of the first time phase with each of the plurality of sub regions in the fundamental image of the second time phase, respectively, and extract a sub region of the plurality of sub regions in the fundamental image, as a first candidate position for a second region of interest in an ultrasonic image based on reflected wave data of the second time phase among the plurality of pieces of reflected wave data,
set, in accordance with a position of a first region of interest in a harmonic image of the first time phase among the plurality of harmonic images, a plurality of sub regions in a harmonic image of the second time phase among the plurality of harmonic images,
compare the first region of interest in the harmonic image of the first time phase with each of the plurality of sub regions in the harmonic image of the second time phase, respectively, and extract a sub region of the plurality of sub regions in the harmonic image, as a second candidate position for the second region of interest in the ultrasonic image based on reflected wave data of the second time phase among the plurality of pieces of reflected wave data,
compare a first similarity between the sub region corresponding to the first candidate position and the first region of interest in the fundamental image with a second similarity between the sub region corresponding to the second candidate position and the first region of interest in the harmonic image, and
set the sub region having a higher similarity between the first similarity and the second similarity, as the second region of interest in the ultrasonic image of the second dine phase, wherein
the second region of interest is an analysis region in which Time Curve Analysis (TCA) relating to administration of the contrast agent is performed.

2. The ultrasonic diagnostic apparatus according to claim 1 , wherein the processing circuitry is configured to
compare a pixel value in the first region of interest in the fundamental image of the first time phase and each pixel value of the plurality of sub regions in the fundamental image of the second time phase, respectively, and extract, as the first candidate position, the sub region having a pixel value most similar to the pixel value in the first region of interest in the fundamental image of the first time phase, and
compare a pixel value in the first region of interest in the harmonic image of the first time phase and each pixel value of the plurality of sub regions in the harmonic image of the second time phase, respectively, and extract, as the second candidate position, the sub region having a pixel value most similar to the pixel value in the first region of interest in the harmonic image of the first time phase.

3. The ultrasonic diagnostic apparatus according to claim 1 , wherein the processing circuitry is configured to set the sub region having the higher similarity between the first similarity and the second similarity as the second region of interest on condition that a variance value of pixel values of a plurality of pixels included in the sub region exceeds a predetermined threshold.

4. The ultrasonic diagnostic apparatus according to claim 1 , wherein the processing circuitry is configured to
extract the sub region corresponding to the first candidate position in each of a fundamental image of a time phase among the plurality of fundamental images in chronological order and a fundamental image of a time phase among the plurality of fundamental images in reverse chronological order based on the fundamental image of the first time phase where the first region of interest is set, and
extract the sub region corresponding to the second candidate position in each of a harmonic image of a time phase among the plurality of harmonic images in the chronological order and a harmonic image of a time phase among the plurality of harmonic images in the reverse chronological order based on the harmonic image of the first time phase where the first region of interest is set.

5. The ultrasonic diagnostic apparatus according to claim 1 , wherein the processing circuitry is configured to set the sub region as the second region of interest on condition that the higher similarity exceeds a predetermined threshold.

6. The ultrasonic diagnostic apparatus according to claim 5 , wherein the processing circuitry is further configured to notify an operator of a warning when the first similarity based on a pixel value in the sub region corresponding to the first candidate position and the second similarity based on a pixel value in the sub region corresponding to the second candidate position are determined to not exceed the predetermined threshold.

7. The ultrasonic diagnostic apparatus according to claim 1 , wherein the second region of interest set in the ultrasonic image of the second time phase has a same shape and a same size as the first region of interest in the fundamental image of the first time phase and the first region of interest in the harmonic image of the first time phase.

8. An image processing apparatus comprising:
processing circuitry configured to
acquire a plurality of fundamental images based on a plurality of pieces of fundamental wave data in time series in which tissue in a subject functions as a reflection source in a plurality of pieces of reflected wave data in time series,
acquire a plurality of harmonic images based on a plurality of pieces of harmonic data in time series in which microbubbles included in a contrast agent function as a reflection source in the plurality of pieces of reflected wave data in time series,
set, in accordance with a position of a first region of interest in a fundamental image of a first time phase among the plurality of fundamental images, a plurality of sub regions in a fundamental image of a second time phase among the plurality of fundamental images,
compare the first region of interest in the fundamental image of the first time phase with each of the plurality of sub regions in the fundamental image of the second time phase, respectively, and extract a sub region of the plurality of sub regions in the fundamental image, as a first candidate position for a second region of interest in an ultrasonic image based on reflected wave data of the second time phase among the plurality of pieces of reflected wave data,
set, in accordance with a position of a first region of interest in a harmonic image of the first time phase among the plurality of harmonic images, a plurality of sub regions in a harmonic image of the second time phase among the plurality of harmonic images,
compare the first r

Assignees

• Toshiba Medical Sys Corp
• Canon Medical Systems Corp

Inventors

• Yao Cong
• Kawagishi Tetsuya
• Mine Yoshitaka
• Yoneyama Naoki
• Yoshiara Hiroki

Classifications

• A61B8/481 Primary

  involving the use of contrast agents, e.g. microbubbles introduced into the bloodstream · CPC title

• A61B8/06

  Measuring blood flow · CPC title

• G01S7/52038

  involving non-linear properties of the propagation medium or of the reflective target · CPC title

• A61B8/5223

  for extracting a diagnostic or physiological parameter from medical diagnostic data (for algorithms to analyse biomedical images G06T7/0012) · CPC title

• A61B8/463

  characterised by displaying multiple images or images and diagnostic data on one display · CPC title