Realistic electro-anatomical model of the mammalian His/Purkinje system

Patent metadata

Field	Value
Publication number	US-11295634-B2
Application number	US-201816208348-A
Country	US
Kind code	B2
Filing date	Dec 3, 2018
Priority date	Dec 4, 2017
Publication date	Apr 5, 2022
Grant date	Apr 5, 2022

Abstract

An electro-anatomical model of the mammalian His/Purkinje system includes a shell simulating the anatomy of at least a portion of a mammalian heart. The shell has a hollow interior and a first port providing an aperture to the interior of the shell. A plug is inserted in the first port so that a surface of the plug is exposed to the interior of the shell. An electrical circuit provides signals to electrodes in the plug which simulate the electrical signals generated by the bundle of His/Purkinje system in vivo. A second port provides access to the interior of the shell for an introducer catheter to locate the simulated bundle of His and to insert a pacing lead therein. The model is useful for developing tools for His pacing and for training users in techniques for implanting His pacing leads.

First claim

The invention claimed is:

1. An electro-anatomical model of the mammalian His/Purkinje system, the model comprising:
a base;
a shell mounted to the base and simulating the anatomy of at least a portion of a mammalian heart, the shell having a hollow interior;
a first port providing an aperture to the interior of the shell;
a plug inserted in the first port, the plug having a surface exposed to the interior of the shell; and
a circuit providing electrical signals to the plug to simulate electrical signals generated by the bundle of His/Purkinje system in vivo.

2. The electro-anatomical model as claimed in claim 1 , wherein the portion of the mammalian heart includes the right atrium and the right ventricle of the heart.

3. The electro-anatomical model as claimed in claim 2 , wherein the portion of the mammalian heart further includes a portion of the superior vena cava.

4. The electro-anatomical model as claimed in claim 1 , wherein the shell is coated with a waterproofing composition.

5. The electro-anatomical model as claimed in claim 4 , wherein the waterproofing composition is coated on an exterior surface of the shell and on an interior surface of the shell.

6. The electro-anatomical model as claimed in claim 1 , wherein the shell includes a second port providing access for a tool to enter the interior of the shell.

7. The electro-anatomical model as claimed in claim 6 , wherein the second port includes a hemostasis valve.

8. The electro-anatomical model as claimed in claim 1 , wherein the exposed surface of the plug includes a material insert simulating tissue of the mammalian heart.

9. The electro-anatomical model as claimed in claim 8 , wherein the material insert in use is electrically conductive.

10. The electro-anatomical model as claimed in claim 9 , wherein the material insert has a structure including open porosity.

11. The electro-anatomical model as claimed in claim 8 , wherein the material insert comprises a polyurethane foam.

12. The electro-anatomical model as claimed in claim 8 , wherein the material insert comprises a conductive gel.

13. The electro-anatomical model as claimed in claim 1 , wherein the plug includes a first electrode connected to the circuit and a second electrode connected to ground, the first electrode being separated from the second electrode.

14. The electro-anatomical model as claimed in claim 13 , wherein the plug includes a physical barrier disposed between the first electrode and the second electrode.

15. The electro-anatomical model as claimed in claim 14 , wherein the exposed surface of the plug includes a material insert simulating tissue of the mammalian heart, the material insert providing a conductive path between the first electrode and the second electrode.

16. The electro-anatomical model as claimed in claim 13 , wherein the interior of the shell includes a conductive fluid, the conductive fluid conducting electrical signals from the first electrode to the second electrode.

17. The electro-anatomical model as claimed in claim 1 , further comprising a first video camera for capturing images at the exposed surface of the plug.

18. The electro-anatomical model as claimed in claim 17 , wherein the shell is mounted to the base by a plurality of stanchions, the first video camera being mounted in one of the stanchions in alignment with the exposed surface of the plug.

19. The electro-anatomical model as claimed in claim 17 , further comprising a second video camera mounted in the base and adapted to capture images in the vicinity of the exposed surface of the plug.

20. A method for simulating the delivery of a pacing lead to the His bundle of a patient's heart, the method comprising:
providing an electro-anatomical model simulating the anatomy of at least a portion of a mammalian heart, the model including a shell with a hollow interior, first and second ports providing apertures to the interior of the shell, and a plug inserted in the first port, the plug having a face exposed to the interior of the shell;
transmitting electrical signals to the plug to simulate electrical signals generated by the bundle of His/Purkinje system in vivo;
providing an introducer catheter having a sheath with an axial lumen, a distal end, an electrode at the distal end, and a pacing lead disposed in the axial lumen;
inserting the introducer catheter through the second port to the interior of the shell until the distal end of the sheath confronts the exposed face of the plug;
moving the distal end of the sheath relative to the exposed face of the plug until the electrode at the distal end of the sheath receives at least a portion of the electrical signals transmitted to the plug; and
deploying the pacing lead from the axial lumen of the sheath and implanting the pacing lead in the exposed face of the plug.

Assignees

• St Jude Medical Cardiology Div Inc

Inventors

• Kramer Scott A
• Belk Paul A
• Tantalean Ii Juan Carlos
• Seeker Gavin P
• Senarith Patrick P
• Stoermer Erich W
• Broman David J

Classifications

• A61N1/056

  Transvascular endocardial electrode systems · CPC title

• A61B2018/00351

  Heart · CPC title

• A61B34/10

  Computer-aided planning, simulation or modelling of surgical operations · CPC title

• G09B23/30 Primary

  Anatomical models {(G09B23/281 - G09B23/288 take precedence)} · CPC title

• A61N1/365

  controlled by a physiological parameter, e.g. heart potential {(evoked response A61N1/371)} · CPC title