Determining a volume of medical fluid pumped into or out of a medical fluid cassette

Patent metadata

Field	Value
Publication number	US-11291753-B2
Application number	US-201816143000-A
Country	US
Kind code	B2
Filing date	Sep 26, 2018
Priority date	Aug 21, 2013
Publication date	Apr 5, 2022
Grant date	Apr 5, 2022

Abstract

A method that includes pumping medical fluid out of or drawing medical fluid into a chamber of a medical fluid cassette, calculating a theoretical volume of fluid pumped out of or drawn into the chamber, and multiplying the theoretical volume of fluid pumped out of or drawn into the chamber by a correction factor to determine a corrected volume of fluid pumped out of or drawn into the chamber.

First claim

What is claimed is:

1. A medical fluid pumping system comprising:
a medical fluid cassette comprising a flexible membrane that at least partially defines a pump chamber; and
a medical fluid pumping machine defining a compartment configured to receive the medical fluid cassette, the medical fluid pumping machine comprising
a piston that is aligned with the pump chamber of the medical fluid cassette when the medical fluid cassette is disposed within the compartment, the piston being operable to pump medical fluid out of or draw medical fluid into the pump chamber of the medical fluid cassette, wherein a pressure of the medical fluid in the medical fluid cassette during pumping of the medical fluid causes the membrane of the medical fluid cassette to bulge around a perimeter of a piston head of the piston of the medical fluid pumping machine; and
a control unit that is operable to calculate a theoretical volume of fluid pumped out of or drawn into the pump chamber and is operable to multiply the theoretical volume of fluid pumped out of or drawn into the pump chamber by a correction factor to determine a corrected volume of fluid pumped out of or drawn into the pump chamber, wherein the correction factor corresponds to an amount of bulging of the membrane of the medical fluid cassette around the perimeter of the piston head during pumping of the medical fluid.

2. The medical fluid pumping system of claim 1 , wherein the medical fluid cassette comprises a rigid base that cooperates with the flexible membrane to at least partially form the chamber.

3. The medical fluid pumping system of claim 2 , wherein the medical fluid cassette comprises a fastening member attached to the flexible membrane, the fastening member defining a recess configured to receive the piston head of the piston of the medical fluid pumping machine, and the fastening member having an engagement surface that engages an engagement surface of the piston head when the piston head is disposed in the recess such that, when the piston head is disposed in the recess and is moved linearly away from the base of the cassette, the engagement surface of the piston head is engaged with the engagement surface of the fastening member and pulls the fastening member and the flexible membrane to which the fastening member is attached away from the base to increase a volume of the pump chamber.

4. The medical fluid pumping system of claim 2 , wherein the membrane of the medical fluid cassette is configured to be driven to decrease a volume of the chamber and is configured to be driven to increase the volume of the chamber.

5. The medical fluid pumping system of claim 4 , wherein the membrane is configured to be driven by the piston.

6. The medical fluid pumping system of claim 5 , wherein the piston comprises the piston head attached to a piston shaft.

7. The medical fluid pumping system of claim 6 , wherein the piston head is substantially dome-shaped or mushroom head shaped.

8. The medical fluid pumping system of claim 5 , wherein the piston is configured to drive the membrane of the medical fluid cassette to decrease the volume of the chamber, and wherein the control unit is configured to calculate the theoretical volume of fluid pumped out of the chamber, and wherein the control unit is configured to multiply the theoretical volume of fluid pumped out of the chamber by the correction factor to determine the corrected volume of fluid pumped out of the chamber.

9. The medical fluid pumping system of claim 5 , wherein the piston is configured to be retracted to pull the membrane of the medical fluid cassette to increase the volume of the chamber, wherein the control unit is configured to calculate the theoretical volume of fluid drawn into the chamber, and wherein the control unit is configured to multiply the theoretical volume of fluid drawn into the chamber by the correction factor to determine the corrected volume of fluid drawn into the chamber.

10. The medical fluid pumping system of claim 6 , wherein at least a portion of the piston head has an outer diameter that is less than a maximum inner diameter of a recessed region of the rigid base that cooperates with the membrane to form the chamber.

11. The medical fluid pumping system of claim 1 , wherein the medical fluid pumping machine is configured to repeat the steps of:
(a) pumping the medical fluid out of or drawing the medical fluid into the chamber of the medical fluid cassette;
(b) calculating, the theoretical volume of the medical fluid pumped out of or drawn into the chamber; and
(c) multiplying the theoretical volume of fluid pumped out of or drawn into the chamber by the correction factor to determine the corrected volume of fluid pumped out of or drawn into the chamber,
wherein the control unit is configured to sum the determined corrected volumes to determine a total corrected volume of fluid pumped out of or drawn into the chamber over the course of a dialysis treatment.

12. The medical fluid pumping system of claim 11 , wherein the dialysis treatment comprises pumping dialysate out of the pump chamber and into a peritoneal cavity of a patient multiple times and drawing the dialysate out of the peritoneal cavity of the patient and into the pump chamber multiple times, and the medical fluid pumping machine is configured to carry out steps (a)-(c) each time the dialysate is pumped out of the pump chamber and into the peritoneal cavity of the patient and each time the dialysate is drawn out of the peritoneal cavity of the patient and into the pump chamber to determine a total volume of dialysate delivered to the peritoneal cavity of the patient and a total volume of dialysate removed from the peritoneal cavity of the patient during the dialysis treatment.

13. The medical fluid pumping system of claim 1 , wherein the medical fluid pumping machine is configured to measure a pressure of the medical fluid within the medical fluid cassette or within a fluid line connected to the medical fluid cassette and the control unit is configured to select the correction factor based on the measured pressure.

14. The medical fluid pumping system of claim 13 , wherein the medical fluid pumping machine comprises a pressure sensor configured to align with a pressure sensing chamber of the medical fluid cassette when the medical fluid cassette is in the compartment of the medical fluid pumping machine.

15. The medical fluid pumping system of claim 14 , wherein a pressure in the pressure sensing chamber is approximately equal to the pressure in the pump chamber of the medical fluid cassette.

16. The medical fluid pumping system of claim 13 , further comprising isolating the pump chamber prior to measuring the pressure.

17. The medical fluid pumping system of claim 16 , wherein isolating the pump chamber comprises closing valves adjacent first and second ports of the pump chamber.

18. The medical fluid pumping system of claim 1 , wherein the medical fluid pumping machine comprises a peritoneal dialysis machine.

Assignees

• Fresenius Medical Care Holdings Inc

Inventors

• Ly Tri
• Zhu Jie
• Plahey Kulwinder S

Classifications

• A61M1/281 Primary

  Instillation other than by gravity · CPC title

• A61M1/288

  Priming (priming in extracorporeal blood circuits A61M1/3643) · CPC title

• A61M2205/3379

  Masses, volumes, levels of fluids in reservoirs, flow rates · CPC title

• G01F22/00

  Methods or apparatus for measuring volume of fluids or fluent solid material, not otherwise provided for · CPC title

• G01F22/02

  involving measurement of pressure · CPC title