Docking stations for transcatheter valves

Patent metadata

Field	Value
Publication number	US-11291540-B2
Application number	US-201816034794-A
Country	US
Kind code	B2
Filing date	Jul 13, 2018
Priority date	Jun 30, 2017
Publication date	Apr 5, 2022
Grant date	Apr 5, 2022

Abstract

Docking stations for transcatheter valves are described. The docking stations can include an expandable frame, at least one sealing portion, and a valve seat. The expandable frame can be configured to conform to an interior shape of a portion of the circulatory system when expanded inside the circulatory system. The sealing portion can be configured to contact an interior surface of the circulatory system to create a seal. The valve seat can be connected to the expandable frame and can be configured to support an expandable transcatheter valve. The docking stations are adaptable to different anatomies/locations to allow implantation of a transcatheter valve in a variety of anatomies/locations.

First claim

The invention claimed is:

1. A docking station comprising:
an expandable frame configured to conform to an interior shape of a blood vessel when expanded inside the blood vessel, the expandable frame including an annular outer wall extending from a proximal end to a distal end portion and an annular inner wall radially spaced from the annular outer wall and having a proximal end that terminates in the distal end portion of the annular outer wall such that the annular inner wall is limited to the distal end portion of the annular outer wall;
at least one sealing portion defined by the annular outer wall and configured to provide a seal between the docking station and an interior surface of the blood vessel; and
a valve seat defined by the annular inner wall, wherein the valve seat is configured to support an expandable transcatheter valve at the distal end portion of the expandable frame;
wherein the expandable frame includes a first leg that extends proximally beyond the proximal end of the annular outer wall and an elongated second leg that extends proximally further beyond the proximal end of the annular outer wall, beyond a proximal end of the first leg.

2. The docking station of claim 1 , wherein links connect the annular outer wall of the expandable frame to the annular inner wall of the expandable frame.

3. The docking station of claim 2 , wherein the links are curved in a semi-circular shape.

4. The docking station of claim 2 , wherein the outer wall of the expandable frame comprises a plurality of struts, and wherein a thickness of the links is less than a thickness of the struts.

5. The docking station of claim 2 , wherein an apex of the links is bent such that portions of the links on opposite sides of the apex extend away from each other at an acute angle.

6. An expandable docking station frame comprising:
an annular valve seat having a distal end;
a cylindrical outer wall having a distal end comprising struts disposed around the valve seat; and
links that connect the distal end of the annular valve seat to the distal end of the outer wall, each of the links being contoured distally outward of the distal ends of the annular valve seat and the outer wall to form an apex defining a distal end of the expandable docking station frame; and
wherein each of the links extends from the outer wall directly toward a longitudinal axis that runs longitudinally through a center of the docking station frame; and
wherein a thickness of the links is less than a thickness of the struts.

7. The expandable docking station frame of claim 6 , further comprising a first leg that extends proximally beyond a proximal end of the cylindrical outer wall and an elongated second leg that extends proximally further beyond the proximal end of the cylindrical outer wall, beyond a proximal end of the first leg.

8. The docking station of claim 1 , wherein the elongated second leg includes a foot shaped for connection to a retention device.

9. The docking station of claim 1 , wherein the expandable frame is configured to conform to the interior shape of the blood vessel, when expanded inside the blood vessel, such that the expandable frame can expand in multiple locations to conform to multiple bulges of the blood vessel and can contract in multiple locations to conform to multiple narrowed regions of the blood vessel.

10. The docking station of claim 9 , wherein the blood vessel is an aorta, and wherein the expandable frame is configured to conform to an interior shape of the aorta when expanded inside the aorta.

11. The docking station of claim 1 , further comprising a tubular graft coupled to the expandable frame that extends axially beyond an end of the expandable frame.

12. The expandable docking station frame of claim 6 , wherein the links and the struts are integrally formed, and wherein a transition portion transitions from the thickness of the links to the thickness of the struts.

13. The expandable docking station frame of claim 6 , wherein an apex of the links is bent such that portions of the links on opposite sides of the apex extend away from each other at an acute angle.

14. A docking station comprising:
a frame comprising a retaining portion circumscribing an inflow area and a valve seat configured to receive an expandable transcatheter valve, wherein the retaining portion has a first diameter larger than a second diameter of the valve seat, and wherein a tapered region transitions between the first diameter and the second diameter in an inflow to outflow direction, such that the valve seat is positioned entirely to one axial side of the retaining portion without radially overlapping any of the retaining portion;
at least one sealing portion configured to provide a seal between the docking station and an interior surface of a circulatory system; and
a reinforcing material connected to the frame at the valve seat for preventing transfer of radial outward force from the valve seat to the interior surface of the circulatory system.

15. The docking station of claim 14 , further comprising a toroidal atraumatic outer segment that extends radially outwardly from the valve seat.

16. The docking station of claim 14 wherein the at least one sealing portion comprises a cover disposed over the tapered region of the frame.

17. The docking station of claim 14 wherein the at least one sealing portion comprises a cover disposed over the tapered region of the frame and a portion of the retaining portion of the frame.

18. The docking station of claim 17 wherein a majority of the retaining portion of the frame is uncovered.

19. The docking station of claim 14 wherein the reinforcing material comprises a band connected to the frame at the valve seat.

20. A docking station comprising:
a frame comprising a retaining portion circumscribing an inflow area and a valve seat;
wherein the retaining portion has a first diameter larger than a second diameter of the valve seat;
wherein a tapered region of the frame transitions between the first diameter and the second diameter in an inflow to outflow direction;
wherein the valve seat is disposed at an end of the frame, positioned entirely to one axial side of the retaining portion without overlapping any of the retaining portion;

a cover having a portion disposed over the tapered region of the frame to define a sealing portion configured to provide a seal between the tapered portion of the frame and an interior surface of a circulatory system; and
a reinforcing material separate from the cover and secured around the frame at a junction between the valve seat and the tapered region to restrict radial expansion of the valve seat.

21. The docking station of claim 20 wherein a majority of the retaining portion of the frame is uncovered.

22. The docking station of claim 20 wherein the reinforcing material comprises a band connected to the frame at the valve seat.

23. The docking station of claim 20 wherein the cover is disposed on a portion of the retaining portion.

24. A docking station and valve assembly comprising:
a docking station comprising:
a first frame comprising a retaining portion circumscribing an inflow area and a valve seat;
wherein the retaining portion has a first diameter larger than a second diameter of the valve seat;
wherein a tapered region of the frame transitions between the first diameter and the second diameter in an inflow to outflow direction;
wherein the valve seat is dispose

Assignees

• Edwards Lifesciences Corp

Inventors

• Tayeb Liron
• Goldberg Eran
• Maimon David
• Carmi Adi
• Tylis Arie
• Witzman Ofir
• Schneider Ralph
• Jafari Mohammad
• Cao Hengchu
• Abbott Eason Michael
• Armer Dustin P
• Franklin Michael D
• Saar Tomer
• Dvorsky Anatoly
• Desrosiers John J
• Murray Daniel James
• Valdez Michael G
• Bash Assaf
• Blumenfeld Amir
• Axelrod Noa
• Atias Eitan

Classifications

• A61F2/2412

  with soft flexible valve members, e.g. tissue valves shaped like natural valves · CPC title

• A61F2220/005

  using adhesives · CPC title

• A61F2/9522

  Means for mounting a stent or stent-graft onto or into a placement instrument · CPC title

• A61F2250/0039

  differing in diameter · CPC title

• A61F2002/9534

  for repositioning of stents · CPC title