Ultraviolet sterilizing drainage catheter

Patent metadata

Field	Value
Publication number	US-11285293-B2
Application number	US-201816216076-A
Country	US
Kind code	B2
Filing date	Dec 11, 2018
Priority date	Nov 6, 2013
Publication date	Mar 29, 2022
Grant date	Mar 29, 2022

Abstract

A device disclosed herein includes a tubular member which is flexible and configured to receive ultraviolet (UV) light from a UV illumination coupler. The tubular member contains a lumen defining a longitudinal interior space within the tubular member, a tubular body bounded by an inner wall defining an outer boundary of the lumen and an outer wall defining an outer surface of the tubular member, at least one optical fiber disposed outside of the interior space not parallel to an axis of the lumen and adapted to receive the UV light from the UV illumination coupler, and a protective component adapted to prevent substantively all of the UV light emitted from the optical fiber from exiting the outer wall. Methods for producing and using such devices are also disclosed herein.

First claim

What is claimed is:

1. A device configured to receive ultraviolet (UV) light from a UV illumination coupler, the device comprising:
a tubular member comprising a tubular body and a longitudinal interior space,
wherein the tubular body is bounded by
an inner wall defining an inner surface of the tubular body, the inner wall facing the longitudinal interior space and the inner wall defining an outer boundary of the longitudinal interior space, and
an outer wall defining an outer surface of the tubular body; and

at least one optical fiber in a helix shape disposed within the tubular member with an axis parallel to an axis of the longitudinal interior space, the at least one optical fiber further disposed within UV transmissive material of the tubular member forming a non-smooth bore and wherein the at least one optical fiber is adapted to emit substantially all UV light from the UV illumination coupler into the longitudinal interior space.

2. The device of claim 1 , wherein the tubular member is flexible.

3. The device of claim 1 , wherein the at least one optical fiber is disposed within the tubular body.

4. The device of claim 1 , wherein a distal end of the at least one optical fiber comprises a reflective surface to reflect light reaching the distal end of the at least one optical fiber back into the tubular member.

5. The device of claim 1 , further comprising a protective component adapted to prevent substantially all of the UV light emitted from the optical fiber from exiting the tubular member.

6. The device of claim 5 , wherein:
the protective component is a UV reflective material disposed between the at least one optical fiber and the outer wall; or
the protective component is a UV reflective coating forming the outer wall.

7. The device of claim 5 , wherein:
the tubular body comprises a UV transmissive inner section comprising the at least one optical fiber embedded in the UV transmissive material and situated at or near the inner wall; and
the protective component comprises a UV absorbent outer section comprising a UV absorbent material situated at or near the outer wall.

8. The device of claim 1 , wherein the at least one optical fiber is at least one diffusive optical fiber to direct a portion of UV light radially from a longitudinal axis of the fiber.

9. The device of claim 1 , wherein the at least one optical fiber is adapted to emit UV light along at least a portion of a length of the longitudinal interior space and wherein the at least one optical fiber is at least one non-diffusive diffusive optical fiber configured to terminate at the portion of the length of the longitudinal interior space to be illuminated.

10. The device of claim 1 , wherein the at least one optical fiber is a bundle of optical fibers.

11. The device of claim 1 , wherein the at least one optical fiber is embedded within the inner wall of the tubular body.

12. The device of claim 1 , further comprising:
a port in fluid communication with the longitudinal interior space and situated at a proximal end of the tubular member; and
an opening in fluid communication with the longitudinal interior space and situated at a distal end of the tubular member.

13. The device of claim 1 , further comprising at least one light source adapted to emit the UV light to illuminate the UV illumination coupler.

14. The device of claim 13 , further comprising:
a power source;
a power socket adapted to transmit current from the power source to the light source; and
a current controller adapted to control current from the power source to the light source.

15. The device of claim 13 , wherein the light source is adapted to emit the UV light having a wavelength of about 250 nm to about 300 nm.

16. The device of claim 13 , wherein the light source is selected from a group comprising a light emitting diode (LED), a laser diode (LD), a superluminescent light emitting diode (SLED), a nanodot LED, a quantum dot, a laser and a combination thereof.

17. The device of claim 1 , wherein the at least one optical fiber is disposed within the tubular member such that the at least one optical fiber encircles a circumference of the longitudinal interior space.

18. A method for producing the device of claim 1 , the method comprising:
affixing the at least one optical fiber to a flexible material to form a fiber-containing structure;
rolling the fiber-containing structure to form a rolled structure defining a hollow space corresponding to the longitudinal interior space;
sealing the rolled structure to form the tubular member; and
attaching the ultraviolet illumination coupler to the tubular member.

19. A treatment method using the device of claim 1 , the method comprising:
inserting a distal end and a portion of the tubular member into a body cavity, duct or vessel of a subject;
passing a liquid or a solid object through the longitudinal interior space; and
transmitting the UV light through the UV illumination coupler to illuminate at least a portion of the longitudinal interior space with a sufficient dose of UV light to inactivate a therapeutically effective amount of infective agents.

20. The treatment method of claim 19 , wherein the therapeutically effective amount is a reduction of bacteria contained in the longitudinal interior space by at least two orders of magnitude while producing no measurable UV-induced damage in tissues of the subject.

Assignees

• The Univ Of Maryland Baltimore
• Us Veterans Affairs
• Univ Maryland

Inventors

• Tang Cha-Min
• Bigeleisen Paul E
• Galvagno Jr Samuel M
• Shirtliff Mark E

Classifications

• A61M25/0017 Primary

  specially adapted for long-term hygiene care, e.g. urethral or indwelling catheters to prevent infections · CPC title

• A61M25/04

  in the body, e.g. expansible {(A61M25/10, A61M16/0488 take precedence)} · CPC title

• A61M25/0012

  with embedded structures, e.g. coils, braids, meshes, strands or radiopaque coils · CPC title

• A61M2205/587

  Lighting arrangements · CPC title

• A61M25/0045

  multi-layered, e.g. coated (coating materials A61L29/08) · CPC title