Microfluidic device and control equipment for microfluidic device

Patent metadata

Field	Value
Publication number	US-11278896-B2
Application number	US-201716758123-A
Country	US
Kind code	B2
Filing date	Dec 22, 2017
Priority date	Oct 27, 2017
Publication date	Mar 22, 2022
Grant date	Mar 22, 2022

Abstract

Provided is a microfluidic device to more easily and effectively operate a valve by improving the structure of valves for controlling a fluid flow more simply and efficiently, which comprises a platform having at least one chamber, at least one flow channel connected to the chambers and transfer fluid, and a valve which opens or closes the flow channel, wherein the valve comprises a body installed in the platform, a blocking plate installed in the body and positioned to face the flow channel to selectively blocks the flow channel, a pressing rod installed to be movable at the inside of the body to press the blocking plate, and a fixing unit installed at the body and fix the pressing rod at a blocking plate pressing position.

First claim

What is claimed is:

1. A microfluidic device comprising:
a platform having at least one chamber; at least one flow channel connected to the chamber and transfer fluid; and a valve which opens or closes the flow channel,
wherein the valve comprises a body installed in the platform, a blocking plate installed in the body and positioned to face the flow channel to selectively blocks the flow channel, a pressing rod installed to be movable at the inside of the body to press the blocking plate, and a fixing unit installed at the body and fix the pressing rod at a blocking plate pressing position and
wherein the fixing unit comprises an elastic latch installed at a side of the body, wherein a front end of the elastic latch is elastically urged towards the inside of the body to latch a front end of the pressing rod for fixing the pressing rod.

2. The microfluidic device of claim 1 , wherein:
the front end of the pressing rod has a locking member which is configured to be locked by the elastic latch,
and a diameter of the locking member is smaller than an internal diameter of the body and larger than an internal diameter of the elastic latch.

3. The microfluidic device of claim 2 , wherein:
the pressing rod further comprises a stepped holder which is formed on a side of the pressing rod and configured to be locked by elastic latch to prevent the escape of the pressing rod.

4. The microfluidic device of claim 1 , wherein:
wherein the blocking plate is made of material having elasticity, and being pressed and transformed by the pressing rod to open and close the flow channel.

5. The microfluidic device of claim 1 ,
further comprises a protrusion that protrudes from a lower end of the body and presses the blocking plate against the platform for tightly attaching.

6. The microfluidic device of claim 1 ,
further comprises a valve operation unit that open and close the flow channel by moving the pressing rod,
wherein the valve operation unit comprises a pressing unit that is configured to apply external force to the pressing rod of the valve so that the pressing rod is locked by the elastic latch and fixed, and a releasing unit configured to release the pressing rod from fixed condition.

7. The microfluidic device of claim 6 , wherein:
the pressing unit comprises a housing located above the body and has an open bottom; an electromagnet installed within the housing; an electric current supplier that applies current to the electromagnet; and a magnetic material that is installed to be movable in the housing and push the pressing rod as it moves due to a magnetic force from the electromagnet to moves the pressing rod.

8. The microfluidic device of claim 7 , wherein:
a diameter of a lower end of the magnetic material is smaller than a diameter of a locking member of the pressing rod.

9. The microfluidic device of claim 7 , wherein:
the releasing unit comprises a driving unit which is connected to the housing and moves the housing toward inside of the body, wherein a diameter of a lower end of the housing, which heads for the body, is equal or smaller than an internal diameter of the body and equal or larger than a diameter of a locking member of the pressing rod, thus the housing enlarges the elastic latch outward as the housing moves into the inside of the body.

10. A control equipment for microfluidic device comprising:
a platform having at least one chamber; at least one flow channel connected to the chamber and transfer fluid; and a valve which opens or closes the flow channel,
wherein the valve comprises a body installed in the platform, a blocking plate installed in the body and positioned to face the flow channel to selectively block the flow channel, a pressing rod installed to be movable at the inside of the body to press the blocking plate, and an elastic latch installed at the side of the body, wherein a front end of the elastic latch is elastically urged towards the inside of the body to latch a front end of the pressing rod for fixing the pressing rod,
wherein the control equipment further comprises a valve operation unit for opening and closing the valve equipped with the microfluidic device, and a moving unit for moving the valve operation unit,
wherein the valve operation unit comprises a pressing unit that is configured to apply external force to the pressing rod of the valve so that the pressing rod is locked by the elastic latch and fixed, and a releasing unit configured to release the pressing rod from a fixed condition.

11. Control equipment for microfluidic device of claim 10 , wherein:
the pressing unit comprises a housing located above the body and has an open bottom; an electromagnet installed within the housing; an electric current supplier that applies current to the electromagnet; and a magnetic material that is installed to be movable in the housing and push the pressing rod as it moves due to a magnetic force from the electromagnet to moves the pressing rod.

12. Control equipment for microfluidic device of claim 11 , wherein:
a diameter of a lower end of the magnetic material is smaller than a diameter of a locking member of the pressing rod.

13. Control equipment for microfluidic device of claim 11 , wherein:
the releasing unit comprises a driving unit which is connected to the housing and moves the housing toward inside of the body, wherein a diameter of a lower end of the housing, which heads for the body, is equal or smaller than an internal diameter of the body and equal or larger than a diameter of the locking member of the pressing rod, thus the housing enlarges the elastic latch outward as the housing moves into the inside of the body.

14. The microfluidic device of claim 4 ,
further comprises a valve operation unit that open and close the flow channel by moving pressing rod,
wherein the valve operation unit comprises a pressing unit that is configured to apply external force to the pressing rod of the valve so that the pressing rod is locked by the elastic latch and fixed, and releasing unit configured to release the pressing rod from fixed condition.

15. The microfluidic device of claim 5 ,
further comprises a valve operation unit that open and close the flow channel by moving pressing rod,
wherein the valve operation unit comprises a pressing unit that is configured to apply external force to the pressing rod of the valve so that the pressing rod is locked by the elastic latch and fixed, and releasing unit configured to release the pressing rod from fixed condition.

Assignees

• Ulsan Nat Inst Science & Tech Unist
• Clinomics Co

Inventors

• Cho Yoon Kyoung
• Lee Kyusang
• Lee Yongjin

Classifications

• F16K2099/0069

  Bistable microvalves · CPC title

• B01L3/502738 Primary

  characterised by integrated valves (throttle valves in microfluidic sample containers B01L3/502746) · CPC title

• B01L2300/06

  Auxiliary integrated devices, integrated components · CPC title

• B01L2300/0806

  Standardised forms, e.g. compact disc [CD] format · CPC title

• B01L2300/123

  Flexible; Elastomeric · CPC title