Method for controlling fluid accuracy and backflow compensation

Patent metadata

Field	Value
Publication number	US-11278853-B2
Application number	US-201816013050-A
Country	US
Kind code	B2
Filing date	Jun 20, 2018
Priority date	Mar 13, 2013
Publication date	Mar 22, 2022
Grant date	Mar 22, 2022

Abstract

A method for controlling fluid ratio accuracy during a dual flow injection with a powered injection system is described. The method includes predicting a first capacitance volume of a first syringe comprising a first medical fluid and a second capacitance volume of a second syringe comprising a second medical fluid with a first capacitance correction factor and a second capacitance correction factor, respectively, selecting a ratio of the first medical fluid and the second medical fluid to be administered to a patient in the dual flow injection, determining a relative acceleration ratio of a first piston of the first syringe and a second piston of a second syringe based on the predicted first capacitance volume and the predicted second capacitance volume, wherein the relative acceleration ratio is selected to maintain the selected ratio of the first medical fluid and the second medical fluid during the dual flow injection, and injecting a mixture of a first medical fluid and a second medical fluid having the selected ratio with the powered injection system.

First claim

We claim:

1. A method for controlling fluid ratio accuracy during a dual flow injection with a fluid delivery system including a powered fluid injector, the method comprising:
selecting, using a fluid control module operatively associated with the powered fluid injector, at least one capacitance correction factor for predicting and compensating for a first capacitance volume of a first syringe comprising a first medical fluid and a second capacitance volume of a second syringe comprising a second medical fluid;
selecting, using the fluid control module operatively associated with the powered fluid injector, a ratio of the first medical fluid and the second medical fluid to be administered to a patient in the dual flow injection;
determining, using the fluid control module operatively associated with the powered fluid injector, a relative acceleration ratio of a first piston of the first syringe and a second piston of the second syringe based on the at least one capacitance correction factor, wherein the relative acceleration ratio is selected to maintain the selected ratio of the first medical fluid and the second medical fluid during the dual flow injection; and
injecting a mixture of the first medical fluid and the second medical fluid having the selected ratio with the fluid delivery system.

2. The method of claim 1 , wherein the first medical fluid has a different viscosity than the second medical fluid.

3. The method of claim 2 , wherein the first medical fluid has a higher viscosity than the second medical fluid.

4. The method of claim 3 , wherein the first medical fluid is an imaging contrast agent and the second medical fluid is saline.

5. The method of claim 4 , wherein the ratio ranges from 10:90 to 90:10 imaging contrast agent to saline.

6. The method of claim 1 , wherein the first piston of the first syringe is accelerated at an acceleration value A 1 , where the acceleration value A 1 is determined by equation (1),
A 1 =A 2 /( c ·( V 1 /V 2 ))  (1)

wherein A 2 is an acceleration value for the second syringe, c is a scalar correction factor derived from the at least one capacitance correction factor, V 1 is a velocity of the first piston, and V 2 is a velocity of the second piston.

7. The method of claim 6 , wherein A 2 is a maximum acceleration value of the second syringe.

8. The method of claim 1 , wherein the fluid delivery system further comprises a first tubing set connected to a distal end of the first syringe and a second tubing set connected to a distal end of the second syringe.

9. The method of claim 8 , wherein a backflow volume of the first medical fluid into the second tubing set is less than 0.5 mL.

Assignees

• Bayer Healthcare Llc

Inventors

• Schriver Ralph H
• Maihoefer Andreas
• Dedig James A
• Spohn Michael A
• Grubic Herbert M
• Swantner Michael J
• Caruso Adam

Classifications

• B01F2101/2202

  Mixing compositions or mixers in the medical or veterinary field · CPC title

• A61M39/105

  Multi-channel connectors or couplings, e.g. for connecting multi-lumen tubes (multi-channel connectors in general F16L37/56) · CPC title

• Y10T137/0329

  Mixing of plural fluids of diverse characteristics or conditions · CPC title

• A61M2039/0027

  for mixing several substances from different containers · CPC title

• B01F35/51

  characterised by their material · CPC title