Apparatus for invitro control of degradation rate of artificial bone, degradation method, and artificial bone

Patent metadata

Field	Value
Publication number	US-11278429-B2
Application number	US-201916518734-A
Country	US
Kind code	B2
Filing date	Jul 22, 2019
Priority date	Oct 25, 2018
Publication date	Mar 22, 2022
Grant date	Mar 22, 2022

Abstract

An apparatus for controlling a degradation rate of an artificial bone in vitro, a degradation method, and an artificial bone are disclosed. The apparatus includes: a variable resistor; and a wearable component, comprising: a metal wire electrically connected in series with the variable resistor and configured to generate an alternating magnetic field; and an insulating textile layer by which the outside of the metal wire is covered.

First claim

We claim:

1. A method for degrading an artificial bone in situ using an apparatus for invitro control of a degradation rate of an artificial bone, the apparatus comprising: a variable resistor; and a wearable component, the wearable component comprising: a metal wire electrically connected in series with the variable resistor and configured to generate an alternating magnetic field; and an insulating textile layer covering the metal wire and matching with a shape of an object in which the artificial bone is to be used, the method comprising:
adjusting a resistance value of the variable resistor to control strength of the alternating magnetic field of the apparatus, so as to control the degradation rate of the artificial bone.

2. The method according to claim 1 , wherein the step of adjusting the resistance value of the variable resistor to control strength of the alternating magnetic field of the apparatus comprises steps of:
determining the strength of the alternating magnetic field of the apparatus according to a predetermined degradation rate of the artificial bone; and
determining the resistance value of the variable resistor according to the strength of the alternating magnetic field of the apparatus.

3. The method according to claim 2 , wherein the degradation rate of the artificial bone is proportional to the strength of the alternating magnetic field of the apparatus.

4. The method according to claim 3 , wherein the strength of the alternating magnetic field of the apparatus is inversely proportional to the resistance value of the variable resistor.

5. The method according to claim 1 , wherein the artificial bone is a magnesium alloy bone having a protective film provided on a surface thereof, and the method further comprises:
adjusting the resistance value of the variable resistor according to the degradation rate of the protective film.

6. The method according to claim 5 , wherein after the protective film is degraded, the method further comprises:
increasing the resistance value of the variable resistor according to a predetermined degradation rate of the magnesium alloy bone.

7. An artificial bone which is degradable by using the apparatus method according to claim 1 , the artificial bone comprising:
a titanium alloy bone; and/or
a magnesium alloy bone having a protective film provided on a surface thereof.

8. A method of processing the artificial bone according to claim 7 , the method comprising:
removing an oxide layer on a surface of the artificial bone in an oxygen-free environment;
heating the artificial bone in an oxygen-free environment; and
forming a dense oxide layer on the surface of the artificial bone in a pure oxygen environment.

9. The method according to claim 8 , wherein the step of removing an oxide layer on a surface of the artificial bone comprises:
removing the oxide layer by acid.

10. The method according to claim 8 , wherein the step of heating is performed at a temperature of 200 to 300 degrees Celsius.

11. The method according to claim 8 , wherein the step of forming the dense oxide layer is performed for 2-3 hours.

12. The method according to claim 1 , wherein the apparatus further comprises:
a controller electrically connected to the variable resistor, and configured to adjust the resistance value of the variable resistor.

13. The method according to claim 1 , wherein the metal wire is arranged as a helix.

14. The method according to claim 1 , wherein the resistance value of the variable resistor is in a range of 0-200 ohms.

15. The method according to claim 1 , wherein the metal wire is formed of a material comprising at least one of copper, aluminum, or gold.

16. The method according to claim 1 , wherein the apparatus further comprises an alternating current power source electrically connected in series with the variable resistor and the metal wire.

17. The method according to claim 16 , wherein the apparatus further comprises a switching element disposed in a series circuit formed of the metal wire, the variable resistor, and the alternating current power source and configured to control on and off status of the apparatus.

18. The method according to claim 1 , wherein the wearable component has an accommodating space provided therein, wherein the accommodating space is defined by the metal wire and the insulating textile layer.

Assignees

• Fuzhou Boe Optoelectronics Tech Co Ltd
• Boe Technology Group Co Ltd

Inventors

• Cheng Li
• Huang Jianming
• Jia Xiaobo
• Pan Wanping
• Lin Qiusheng
• Wang Ying
• Lin Yabin
• Li Weiqiang
• Zhu Aihua
• Su Xuezhen
• Yu Hailong
• Su Yifeng
• Lu Xiaoying

Classifications

• H01C10/00

  Adjustable resistors · CPC title

• A61F2002/2835

  Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material · CPC title

• C23C8/12

  using elemental oxygen or ozone · CPC title

• H01C10/14

  adjustable by auxiliary driving means · CPC title

• A61F2310/00041

  Magnesium or Mg-based alloys · CPC title