Systems, devices and methods for analyte monitoring system

Patent metadata

Field	Value
Publication number	US-11278244-B2
Application number	US-201715462239-A
Country	US
Kind code	B2
Filing date	Mar 17, 2017
Priority date	Mar 30, 2016
Publication date	Mar 22, 2022
Grant date	Mar 22, 2022

Abstract

Systems and methods are provided for detecting changes or fluctuations in an analyte concentration signal that are abnormal, e.g., exceed a predetermined threshold, current trend of analyte concentration measurements, etc. Signals indicative of an analyte concentration in a host may be received from an analyte sensor. The signals may be monitored, and a determination can be made as to whether there is a change in the signal. Upon detecting such a change, the change can be compensated for such that a representation of the signal indicates the analyte concentration. Optionally, the cause of the detected changes or fluctuations can also be determined and information regarding the detected changes or fluctuations can be recorded and analyzed for subsequent optimization of the systems and methods as well for transmitting alerts, notifications, etc. to a user to take corrective action.

First claim

What is claimed is:

1. A system comprising:
an analyte sensor adapted to measure analyte concentration data;
sensor measurement circuitry adapted to receive analyte concentration data from the analyte sensor and detect a fluctuation including noise in the received analyte concentration data, wherein the sensor measurement circuitry is further adapted to compensate for the detected fluctuation exceeding a predetermined threshold in the analyte concentration data to accurately reflect analyte concentration in a host; and
an offset current circuit adapted to add an analog current to a signal indicative of the analyte concentration data and a noise signal component associated with the noise such that the signal indicative of the analyte concentration data and the noise signal component are shifted from below-zero levels to levels above a zero value, wherein the offset current circuit is configured to be triggered to add the analog current upon a determination that a percentage of zero-peak value associated with the noise signal component is greater than the signal indicative of the analyte concentration data.

2. The system of claim 1 , further comprising at least one of memory adapted to store information associated with the fluctuation in the analyte concentration data or a transmitter adapted to transmit the information associated with the fluctuation to at least one of a remote server or a display device adapted to display the information associated with the fluctuation or information derived therefrom.

3. The system of claim 2 , comprising one or more environmental sensors to determine environmental conditions configured to cause the fluctuation in the analyte concentration data.

4. The system of claim 1 , wherein the offset current circuit is adapted to add the analog current in accordance with one or more programmed offset currents.

5. The system of claim 4 , further comprising a processor adapted to compensate for the noise signal component and subtract the added analog current from the received analyte concentration data to obtain analyte concentration data indicative of the analyte concentration in the host absent the noise signal component.

6. The system of claim 5 , wherein the processor is further adapted to capture details of the noise signal component by reducing a sampling period during which the analyte concentration data is measured or overclocking the sensor measurement circuitry.

7. The system of claim 1 , further comprising a guard band having a same voltage differential as that existing between at least two electrodes of the analyte sensor to compensate for artifact-induced current flow across the voltage differential.

8. The system of claim 1 , further comprising a processor adapted to directly adjust the analyte concentration data by a predetermined adjustment amount based upon one or more factors causing the fluctuation.

Assignees

• Dexcom Inc

Inventors

• Burnette Douglas William
• Hampapuram Hari
• Kamath Apurv Ullas
• Larvenz Shawn
• Mandapaka Aditya
• Mcdaniel Zebediah L
• Miller Tom
• Wedekind Jeffrey R
• Zeng Yonghuang
• Reichert Stephen Alan

Classifications

• A61B5/72 Primary

  Signal processing specially adapted for physiological signals or for diagnostic purposes · CPC title

• A61B5/1495

  Calibrating or testing of in-vivo probes · CPC title

• A61B5/14865

  invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors · CPC title

• A61B5/1477

  non-invasive · CPC title

• A61B5/1473

  invasive, e.g. introduced into the body by a catheter · CPC title