Polycyclic carbamoylpyridone derivative having hiv integrase inhibitory activity
US-2016207939-A1 · Jul 21, 2016 · US
US11267823B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11267823-B2 |
| Application number | US-202016924390-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 9, 2020 |
| Priority date | Apr 28, 2005 |
| Publication date | Mar 8, 2022 |
| Grant date | Mar 8, 2022 |
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Substituted 1,2,3,3a,4,5,7,9,13,13a-decahydropyrido[1′,2′:4,5]pyrazino[1,2-a]pyrrolo[1,2-c]pyrimidines having the anti-virus activity, particularly the HIV integrase inhibitory activity, and a pharmaceutical composition containing the same, particularly an anti-HIV pharmaceutical composition.
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The invention claimed is: 1. A compound of the formula: or a pharmaceutically acceptable salt thereof. 2. A pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent together with the compound of claim 1 , or a pharmaceutically acceptable salt thereof. 3. A pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent together with the compound of claim 1 . 4. A compound of the formula: 5. A pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent together with the compound of claim 4 . 6. A compound of the formula: or a pharmaceutically acceptable salt thereof. 7. A pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent together with the compound of claim 6 , or a pharmaceutically acceptable salt thereof. 8. A pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent together with the compound of claim 6 . 9. A compound of the formula: 10. A pharmaceutical composition comprising a pharmaceutically acceptable carrier or diluent together with the compound of claim 9 .
Ortho-condensed systems · CPC title
Ortho-condensed systems · CPC title
Ortho-condensed systems · CPC title
Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems · CPC title
having two nitrogen atoms, e.g. dilazep · CPC title
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