Systems and methods for improving an AV access site

Patent metadata

Field	Value
Publication number	US-11260160-B2
Application number	US-201514596785-A
Country	US
Kind code	B2
Filing date	Jan 14, 2015
Priority date	Jan 14, 2014
Publication date	Mar 1, 2022
Grant date	Mar 1, 2022

Abstract

The invention relates to restricting flow through a vascular access site such as an arteriovenous (AV) fistula or a graft using intravascular measurements to guide the procedure. The invention provides systems and methods for using intravascular detection to guide the restriction of flow through an AV fistula or graft. An intravascular instrument such as an imaging catheter or guidewire with measuring capabilities is inserted into a vessel proximal to an access site and used to evaluate the access site, which is banded to obtain healthy flow as indicated by the intravascular instrument. In certain aspects, the invention provides a method for improving a hemodialysis fistula or graft by inserting an intravascular instrument into a vessel proximal to the fistula or graft, making a measurement with the intravascular instrument, and restricting flow through the fistula or graft until the measurement obtains a predetermined value.

First claim

The invention claimed is:

1. A method for improving a hemodialysis vascular access site, the method comprising:
providing an intravascular instrument comprising an elongate tubular member, a proximal coil coupled to the elongate tubular member, a tip coil and a combination sensor tip having a housing, the tip coil and the proximal coil being different coils, wherein the housing comprises a proximal end coupled to the tip coil, wherein the combination sensor tip comprises a pressure sensor and an intravascular ultrasound (IVUS) transducer configured to acquire cross-sectional views, wherein the pressure sensor and the IVUS transducer are disposed within the housing;
inserting the intravascular instrument into a vessel proximal to the hemodialysis vascular access site with guidance from imaging provided by the IVUS transducer in the combination sensor tip at the distal end of the intravascular instrument;
making a measurement with the pressure sensor at the distal end of the intravascular instrument; and
restricting flow through the hemodialysis vascular access site by banding while directly monitoring a radius or diameter of the vascular access site undergoing the banding using cross-sectional views acquired by the IVUS transducer until the radius or diameter of the vascular access site determined by the direct monitoring obtains a predetermined value.

2. The method of claim 1 , wherein the intravascular instrument is an instrumented guidewire.

3. The method of claim 1 , wherein the IVUS is further configured to acquire views along a vessel axis, and the inserting of the intravascular instrument into the vessel is with guidance from views along the vessel axis provided by the IVUS transducer.

4. The method of claim 1 , wherein the measurement comprises a rate of flow through the vascular access site and the vascular access site is one selected from the list consisting of an arteriovenus fistula and a graft.

5. The method of claim 1 , wherein the tip coil has at least one distinguishing characteristic from the proximal coil.

6. The method of claim 5 , wherein the at least one distinguishing characteristic is the tip coil is radiopaque.

7. The method of claim 1 , wherein the pressure sensor is disposed proximally of the IVUS transducer within the housing.

8. A system for vascular access site banding, the system comprising:
an intravascular instrument dimensioned to be inserted into a vessel proximal to the vascular access site and operable to measure a property therein, the intravascular instrument comprising an elongate tubular member, a proximal coil coupled to the elongate tubular member, a tip coil coupled to the proximal coil, the tip coil and the proximal coil being different coils, and a combination sensor tip, wherein the combination sensor tip comprises a housing, a pressure sensor and an IVUS transducer configured to acquire both cross-sectional views and views along a vessel axis, wherein the pressure sensor and the IVUS transducer are disposed within the housing, wherein the housing comprises a proximal end coupled to the tip coil; and
a computer coupled to the intravascular instrument and operable to:
receive the measured property from the combination tip of the intravascular instrument and to evaluate a need for restriction of blood flow through the arteriovenous vascular access site based upon the measured property;
monitor banding of the arteriovenous vascular access site by acquiring cross-sectional views using the IVUS and display a radius or diameter of the arteriovenous vascular access site determined from the cross-sectional views during the banding.

9. The system of claim 8 , wherein the intravascular instrument is an instrumented guidewire.

10. The system of claim 8 , wherein the computer is operable to evaluate whether the measured property obtains a predetermined value and to guide a decision about further restriction of flow based upon whether the measured property obtains the predetermined value.

11. The system of claim 10 , wherein the measured property comprises a rate of flow through the vascular access site.

12. The system of claim 11 , wherein the predetermined value is less than 800 mL/min.

13. The system of claim 10 , wherein the measured property comprises a radius or diameter of the vascular access site.

14. The system of claim 13 , wherein the predetermined diameter value is less than 8 mm.

15. The system of claim 8 wherein
the IVUS transducer is further configured to measure Doppler flow velocity;
the measured property further comprises a flow velocity measured using the IVUS; and
the computer is further operable to compute a flow volume based on the flow velocity and further based on the radius or diameter.

16. The system of claim 8 wherein the measured property is a pressure measurement by the pressure sensor that describes a pressure gradient of the arteriovascular access site.

17. The system of claim 8 , wherein the tip coil has at least one distinguishing characteristic from the proximal coil.

18. The system of claim 17 , wherein the at least one distinguishing characteristic is the tip coil is radiopaque.

Assignees

• Volcano Corp
• Philips Image Guided Therapy Corp

Inventors

• Matsubara Bradley S
• Unser John

Classifications

• A61B8/12 Primary

  in body cavities or body tracts, e.g. by using catheters · CPC title

• A61B5/026

  Measuring blood flow {(A61B3/1233, A61B3/1241 take precedence)} · CPC title

• A61B5/02154

  by optical transmission · CPC title

• A61B8/06

  Measuring blood flow · CPC title

• A61M2205/3331

  Pressure; Flow · CPC title