Spectral imaging

Patent metadata

Field	Value
Publication number	US-11253209-B2
Application number	US-201214354191-A
Country	US
Kind code	B2
Filing date	Nov 1, 2012
Priority date	Nov 10, 2011
Publication date	Feb 22, 2022
Grant date	Feb 22, 2022

Abstract

An analyzer (124) includes a quantifier (204) configured to quantify an amount of contrast material representing scar tissue created by ablation for tissue of interest in contrast enhanced imaging data and a recommender (210) configured to generate a signal indicative of a recommendation to further ablate the tissue of interest in response to the quantified amount of the contrast material not satisfying a pre-determined threshold. A method includes obtaining contrast enhanced image data indicative of scar tissue created by ablation of tissue of interest, quantifying an amount of contrast material for the scar tissue in the tissue of interest, and generating a signal indicative of a recommendation to further ablate the tissue of interest in response to the quantified amount of the contrast material not satisfying a pre-determined threshold.

First claim

The invention claimed is:

1. An analyzer, comprising:
a quantifier, comprising processor circuitry, configured to quantify an amount of contrast material in contrast enhanced imaging data generated by a computed tomography imaging scanner emitting poly-energetic x-ray radiation;
a comparator, comprising the processor circuitry, configured to compare a quantified amount with a pre-determined threshold; and
a recommender, comprising the processor circuitry, configured to generate a signal indicative of a recommendation to further ablate the tissue of interest in response to the quantified amount of the contrast material not satisfying a pre-determined threshold, wherein the recommender is configured to generate the signal based on a result of a comparison and one or more rules.

2. The analyzer of claim 1 , wherein the contrast enhanced imaging data include computed tomography contrast enhanced imaging data.

3. The analyzer of claim 1 , wherein the contrast enhanced imaging data include x-ray contrast enhanced imaging data.

4. The analyzer of claim 1 , wherein the ablation is one or more of radio frequency or cryogenic ablation.

5. The analyzer of claim 1 , wherein the tissue of interest is cardiac tissue.

6. The analyzer of claim 1 , wherein the tissue of interest is a tumor.

7. The analyzer of claim 1 , wherein the recommender is configured to generate a signal indicative of a recommendation when there is the recommendation, and the recommender is configured not to generate a signal indicative of a recommendation when there is no recommendation.

8. The analyzer of claim 1 , further comprising:
a combiner, comprising the processor circuitry, configured to combine a contrast image representing the contrast material of the tissue of interest and a structural image of the tissue of interest, wherein a combination of the images is visually presented.

9. The analyzer of claim 8 , wherein the contrast image represents a nano-particle contrast material targeted to at least one of the scar tissue.

10. The analyzer of claim 9 , wherein the nano-particle contrast material includes one or more of bismuth, gold, or gadolinium nano-particles.

11. The analyzer of claim 8 , wherein the quantified amount is presented along with the contrast enhanced image.

12. The analyzer of claim 8 , wherein the quantified amount is visually represented in a graph.

13. The analyzer of claim 8 , wherein the signal indicative of the recommendation is presented along with the contrast enhanced image.

14. The analyzer of claim 8 , wherein the combiner is configured to generate a single imaging data by combining the contrast image representing the contrast material of the tissue of interest and the structural image of the tissue of interest.

15. A method, comprising:
obtaining, by processor circuitry, contrast enhanced image data indicative of scar tissue created by ablation of tissue of interest, wherein the contrast enhanced image data is generated by a computed tomography imaging scanner emitting poly-energetic x-ray radiation;
quantifying, by the processor circuitry, an amount of contrast material for the scar tissue in the tissue of interest;
generating, by the processor circuitry, a signal indicative of a recommendation to further ablate the tissue of interest in response to a quantified amount of the contrast material not satisfying a pre-determined threshold, by comparing the quantified amount with the pre-determined threshold using one or more rules;
combining, by the processor circuitry, a contrast image representing the contrast material of the tissue of interest and a structural image of the tissue of interest; and
visually presenting, by the processor circuitry, at least a combination of the images.

16. The method of claim 15 , wherein the contrast enhanced imaging data includes at least one of computed tomography contrast enhanced imaging data or x-ray contrast enhanced imaging data.

17. The method of claim 15 , wherein the contrast material includes a nano-particle contrast material targeted to at least one of the scar tissue.

18. The method of claim 17 , wherein nano-particles include one or more of bismuth, gold, or gadolinium nano-particles.

Assignees

• Koninklijke Philips Nv

Inventors

• Manzke Robert
• Proksa Roland
• Neubauer Anne Morawski
• Schirra Carsten Oliver

Classifications

• F25B1/00

  Compression machines, plants or systems with non-reversible cycle (F25B3/00, F25B5/00, F25B6/00, F25B7/00, F25B9/00 take precedence) · CPC title

• G06T2207/20221

  Image fusion; Image merging · CPC title

• A61B6/503

  for diagnosis of the heart · CPC title

• A61B6/481

  involving the use of contrast agents · CPC title

• A61B6/032 Primary

  Transmission computed tomography [CT] · CPC title