Test device, reaction apparatus and reactive test method

Patent metadata

Field	Value
Publication number	US-11249076-B2
Application number	US-201414464971-A
Country	US
Kind code	B2
Filing date	Aug 21, 2014
Priority date	Jan 20, 2011
Publication date	Feb 15, 2022
Grant date	Feb 15, 2022

Abstract

A test device having a micro flow channel including a reaction part where a reactant that is reactive to a tested chemical dispersed in a tested fluid is fixed, and at least one actuator for actuating the tested fluid to move in at least one of two opposite sides of the micro flow channel so as to homogenize a density distribution of the tested chemical in the tested fluid. The tested fluid is sent in the micro flow channel a plurality of times.

First claim

What is claimed is:

1. A reactive test method comprising:
sending a tested fluid in a micro flow channel a plurality of times, the micro flow channel disposed oriented horizontally, the micro flow channel including a reaction part having a reactant fixed to a bottom of the micro flow channel thereat, wherein the reactant is reactive to a tested chemical dispersed in the tested fluid;
actuating the tested fluid to move in at least one of two opposite sides of the micro flow channel so as to homogenize a density distribution of the tested chemical in the tested fluid, and
stirring, via one or more of an oscillator, a resonator, or a spiral groove formed in the micro flow channel, the tested chemical and the tested fluid, wherein the oscillator, the resonator, or the spiral groove is disposed in at least one of two opposite sides of the micro flow channel.

2. A reactive test method according to claim 1 , wherein the tested fluid is reciprocated in the micro flow channel.

3. A reactive test method according to claim 1 , wherein the tested fluid is circulated.

4. A reactive test method according to claim 1 , wherein the actuating the tested fluid is carried out in a reservoir that is disposed in at least one of two opposite sides of the micro flow channel, the reservoir having an inner volume larger than a volume of the tested fluid.

5. A reactive test method according to claim 1 , wherein an immune reaction between an antigen in the tested fluid and an antibody fixed in the reaction part as the reactant is carried out in the reaction part.

Assignees

• Otsuka Pharma Co Ltd

Inventors

• Higashino Kusunoki
• Sando Yasuhiro
• Miyata Kenichi

Classifications

• G01N33/54366 Primary

  Apparatus specially adapted for solid-phase testing · CPC title

• B01F31/86

  with vibration of the receptacle or part of it · CPC title

• B01F25/43141

  composed of consecutive sections of helical formed elements · CPC title

• B01F25/431951

  Spirally-shaped baffle · CPC title

• B01L2400/0487

  fluid pressure, pneumatics · CPC title