Method for evaluating the ability of a composition to prevent muscle damage and fatigue; food supplement and drug

Patent metadata

Field	Value
Publication number	US-11246853-B2
Application number	US-201716097416-A
Country	US
Kind code	B2
Filing date	Mar 8, 2017
Priority date	Apr 27, 2016
Publication date	Feb 15, 2022
Grant date	Feb 15, 2022

Abstract

Disclosed is a method for evaluating the ability of a chemical substance or a chemical composition to prevent muscle fatigue and damage induced by physical exertion in humans; edible composition including at least one salt of a multivalent metal cation, at least one compound selected between vitamin E or vitamin E acetate, at least one edible polyphenol compound selected from compounds of the flavonol family, compounds of the anthocyanin family, compounds of the phenolic acid family and compounds of the flavonol family and/or the glucosylated derivatives thereof, in which the molar ratio/is of at least 0.50 and not more than 2.00; its use as a food supplement or for preparing a food supplement composition or as a drug for preventing muscle fatigue and/or muscle damage induced by physical exertion, in a method for the treatment of the human body by therapy.

First claim

The invention claimed is:

1. An edible composition (C A ) consisting essentially of:
zinc gluconate comprising a zinc divalent cation (C METAL ),
at least one compound (V E ), chosen from vitamin E or vitamin E acetate,
at least one edible composition (PP) of polyphenolic compounds chosen from compounds of the flavanol family, compounds of the anthocyanin family, compounds of the phenolic acid family, and compounds of the family of flavonols and/or glucosylated derivatives of compounds of the family of flavonols,
wherein the (C METAL )/(V E ) molar ratio is greater than or equal to 0.50 and less than or equal to 1.50.

2. The composition (CA) as defined in claim 1 , comprising, for 100% of its weight:
From 5% to 50% by weight of the zinc gluconate,
From 1% to 35% by weight of the at least one compound (V E ),
From 0.5% to 80% by weight of the at least one edible composition (PP) of polyphenolic compounds,
From 10% to 93.5% by weight of at least one pharmaceutically and/or nutritionally acceptable processing additive.

3. A food supplement composition comprising a tablet, a gel capsule, a soft capsule, a syrup, a powder, an immediate-release powder, a delayed-release powder, a powder for reconstituted drinks, a liquid, a stick, or a gel comprising the edible composition (C A ) as defined in claim 1 .

4. A food supplement comprising a tablet, a gel capsule, a soft capsule, a syrup, a powder, an immediate-release powder, a delayed-release powder, a powder for reconstituted drinks, a liquid, a stick, or a gel comprising the edible composition (C A ) as defined in claim 2 .

5. An edible composition (C A ) comprising:
zinc gluconate comprising a zinc divalent cation (C METAL ),
at least one compound (V E ), chosen from vitamin E or vitamin E acetate,
at least one edible composition (PP) of polyphenolic compounds chosen from compounds of the anthocyanin family, compounds of the phenolic acid family, and compounds of the flavanol family and/or glucosylated derivatives of compounds of the flavanol family,
wherein the (C METAL )/(V E ) molar ratio is greater than or equal to 0.50 and less than or equal to 1.50, and wherein the composition comprises for 100% of its weight:
from 5% to 40% by weight of the zinc gluconate,
from 8% to 35% by weight of the at least one compound (V E ),
from 1% to 70% by weight of the at least one edible composition (PP) of polyphenolic compounds,
from 15% to 89% by weight of at least one pharmaceutically and/or nutritionally acceptable diluent, flow agent, binder, or disintegrating agent.

Assignees

• Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic

Inventors

• Cattuzzato Laetitia
• Kern Catherine
• De Pooter Ambre

Classifications

• A61K47/36

  Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin · CPC title

• A61K47/22

  Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones · CPC title

• A61K47/12

  Carboxylic acids; Salts or anhydrides thereof · CPC title

• A61K9/0053

  Mouth and digestive tract, i.e. intraoral and peroral administration · CPC title

• A23V2250/2132

  Other phenolic compounds, polyphenols · CPC title