Non-invasive cardiac monitor and methods of using recorded cardiac data to infer a physiological characteristic of a patient

Patent metadata

Field	Value
Publication number	US-11246524-B2
Application number	US-202117174143-A
Country	US
Kind code	B2
Filing date	Feb 11, 2021
Priority date	Feb 12, 2020
Publication date	Feb 15, 2022
Grant date	Feb 15, 2022

Abstract

The present invention relates to a non-invasive cardiac monitoring device that records cardiac data to infer physiological characteristics of a human, such as cardiac arrhythmia. Some embodiments of the invention allow for long-term monitoring of physiological signals. Further embodiments allow for processing of the detected cardiac rhythm signals partially on the wearable cardiac monitor device, and partially on a remote computing system. Some embodiments include a wearable cardiac monitor device for long-term adhesion to a mammal for prolonged detection of cardiac rhythm signals.

First claim

What is claimed is:

1. A system comprising a wearable cardiac monitor device for monitoring cardiac rhythm signal data of a user, the wearable cardiac monitor device comprising:
a watertight housing;
a surface on the housing configured to be sealably engaged to a patient;
an adhesive on the surface configured to remain continuously affixed to the patient for at least 7 days, without removal until completion of monitoring;
at least two electrodes permanently disposed within the housing, positioned to detect continuous cardiac rhythm signals of the patient while the surface is sealably engaged to the patient;
a hardware processor configured to:
select a neural network from a plurality of neural networks, wherein selecting the neural network is based on a first characteristic, wherein the neural network comprises a first subset of layers and a second subset of layers; and
process the detected cardiac rhythm signals through an encoder, wherein the encoder comprises the first subset of layers;
quantize the output of the first subset of layers of the neural network; and

a transmitter, the transmitter configured to transmit the quantized output of the first subset of layers to a computing system.

2. The system of claim 1 , wherein the system further comprises the computing system, wherein the computing system is configured to infer a likelihood of an occurrence of cardiac arrhythmia by processing the quantized output through a decoder, wherein the decoder comprises the second subset of layers, wherein the arrhythmia comprises at least one of: ventricular tachycardia, supraventricular tachycardia, ectopy, ventricular fibrillation, or extended pauses.

3. The system of claim 1 , wherein the system further comprises the computing system, wherein the computing system is configured to infer a likelihood of an occurrence of cardiac arrhythmia by processing the quantized output through a decoder, wherein the decoder comprises the second subset of layers, wherein to infer the likelihood of an occurrence of cardiac arrhythmia comprises inputting the output of the first subset of layers in the second subset of layers, wherein the first subset processed at least 24 hours of continuously detected, stored cardiac rhythm signals.

4. The system of claim 1 , wherein the housing comprises a patient trigger configured to depress and initiate recordation of an instance in time of a perceived cardiac event.

5. The system of claim 1 , wherein the electrodes are disposed entirely within the housing.

6. The system of claim 1 , wherein the system further comprises the computing system, wherein the computing system is configured to infer a likelihood of an occurrence of cardiac arrhythmia by processing the quantized output through a decoder, wherein the decoder comprises the second subset of layers.

7. The system of claim 1 , wherein the hardware processor is further configured to determine an amount of quantization for the output of the encoder based on a second characteristic of the system.

8. The system of claim 7 , wherein the second characteristic comprises a lossless compression performance.

9. The system of claim 7 , wherein the second characteristic comprises a characteristic corresponding to at least one of: processing power of the hardware processor, storage capacity of the system, or network usage for transmitting the quantized output.

10. The system of claim 7 , wherein the second characteristic comprises an accuracy of the encoder.

11. The system of claim 1 , wherein the hardware processor is further configured to select the encoder from a plurality of algorithms based on a second characteristic.

12. A system comprising a wearable cardiac monitor device for monitoring bio-signal data of a user, the wearable device comprising:
an adhesive assembly comprising a housing and a wing, the wing comprising an electrode configured to detect cardiac signals from a user;
a hardware processor configured to:
select a neural network from a plurality of neural networks, wherein
selecting the neural network is based on a first characteristic, wherein the neural network comprises a first subset of layers and a second subset of layers; and
process the detected cardiac signals through an encoder, wherein the encoder comprises the first subset of layers of the selected neural network;
quantize the output of the first subset of layers; and

a transmitter, the transmitter configured to transmit the quantized output of the first subset to a computing system.

13. The system of claim 12 , wherein the system further comprises the computing system, wherein the computing system is configured to infer a likelihood of an occurrence of cardiac arrhythmia by processing the quantized output through a decoder, wherein the decoder comprises the second subset of layers, wherein the computing system is further configured to determine an atrial fibrillation burden from the detected cardiac signals.

14. The system of claim 13 , wherein the atrial fibrillation burden comprises an amount of time spent in atrial fibrillation by the user during a period of time.

15. The system of claim 13 , wherein the atrial fibrillation burden comprises an amount of time spent in atrial fibrillation by the user during a sleep period and during a wake period.

16. A system comprising a wearable device for monitoring bio-signal data of a user, the wearable device comprising:
an assembly comprising an electrode configured to detect cardiac signals from a user;
a hardware processor configured to:
select a neural network from a plurality of neural networks, wherein selecting the neural network is based on a first characteristic, wherein the neural network comprises a first subset of layers and a second subset of layers; and
process the detected cardiac signals through an encoder, wherein the encoder comprises the first subset of layers of the selected neural network;
quantize the output of the first subset of layers of the neural network; and

a transmitter, the transmitter configured to transmit the quantized output of the first subset of layers to a computing system.

17. The system of claim 16 , wherein the hardware processor is configured to process the detected cardiac signals through the first subset of layers of the neural network continuously in substantially real-time of detecting ECG signals.

18. The system of claim 16 , wherein the output of the first subset of layers of the neural network comprises an indication of an R peak.

19. The system of claim 16 , wherein the system further comprises the computing system, wherein the computing system is configured to infer a likelihood of an occurrence of cardiac arrhythmia by processing the quantized output through a decoder, wherein the decoder comprises the second subset of layers, wherein the computing system is further configured to reconstruct the cardiac signals via the second subset of layers.

20. The system of claim 16 , wherein the output of the first subset of layers of the neural network is of a smaller dimensionality than the input of the first subset of layers of the neural network.

21. The system of claim 16 , wherein the first characteristic comprises at least one of: a characteristic of the wearable device, a network characteristic between the wearable device and the computing system.

22. The system of claim 16 , wherein the hardware processor is further configured to compress the output of the first subset of layers of the neural network, wherein to transmit the output o

Assignees

• Irhythm Tech Inc

Inventors

• Szabados Steven
• Tamura Yuriko
• Wang Xixi
• Mathew George

Classifications

• A61B2560/0209

  adapted for power saving · CPC title

• A61B5/6833

  Adhesive patches · CPC title

• A61B5/6823

  Trunk, e.g., chest, back, abdomen, hip · CPC title

• A61B5/352

  Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval · CPC title

• A61B5/257

  using adhesive means, e.g. adhesive pads or tapes · CPC title