Method for manufacturing polymer and flow-type reaction system for manufacturing polymer

Patent metadata

Field	Value
Publication number	US-11242414-B2
Application number	US-202016992079-A
Country	US
Kind code	B2
Filing date	Aug 12, 2020
Priority date	Mar 29, 2018
Publication date	Feb 8, 2022
Grant date	Feb 8, 2022

Abstract

The present invention provides a method for manufacturing a polymer by a flow-type reaction. The method includes introducing a liquid A of an anionic polymerizable monomer, a liquid B of an anionic polymerization initiator, and a polymerization terminator into different flow paths, allowing the liquids to flow in the flow paths, allowing the liquid A and the liquid B to join together, subjecting the monomer to anionic polymerization while the liquids having joined together are flowing to downstream in a reaction flow path, and allowing a solution, which is obtained by the polymerization reaction and flows in the reaction flow path, and the polymerization terminator to join together so as to terminate the polymerization reaction and to obtain a polymer having a number-average molecular weight of 5,000 to 200,000. A static mixer is disposed in the reaction flow path, and a polymer having a number-average molecular weight equal to or greater than 2,000 is introduced into an inlet port of the mixer. The present invention also provides a flow-type reaction system suitable for performing the manufacturing method.

First claim

What is claimed is:

1. A method for manufacturing a polymer in which anionic polymerization reaction is performed by a flow-type reaction, the method comprising:
introducing a liquid A containing an anionic polymerizable monomer, a liquid B containing an anionic polymerization initiator, and a polymerization terminator into different flow paths;
allowing the liquids to flow in the flow paths;
allowing the liquid A and the liquid B to join together;
subjecting the anionic polymerizable monomer to anionic polymerization while the liquids having joined together are flowing to downstream in a reaction flow path;
allowing a solution, which is obtained by the polymerization reaction and flows in the reaction flow path, and the polymerization terminator to join together so as to terminate the polymerization reaction and to obtain a polymer having a number-average molecular weight of 5,000 to 200,000,
wherein a static mixer is disposed in the reaction flow path, and a polymer having a number-average molecular weight equal to or greater than 2,000 is introduced into an inlet port of the static mixer.

2. The method for manufacturing a polymer according to claim 1 ,
wherein a flow rate at which the liquid B is introduced is higher than 10 mL/min and equal to or lower than 2,000 mL/min.

3. The method for manufacturing a polymer according to claim 1 ,
wherein both the flow path through which the liquid A flows and the flow path through which the liquid B flows have an equivalent diameter of 1 to 10 mm.

4. The method for manufacturing a polymer according to claim 1 ,
wherein a monomer conversion rate is equal to or higher than 1.0% at the inlet port of the static mixer.

5. The method for manufacturing a polymer according to claim 1 ,
wherein an equivalent diameter of the static mixer is 2 to 100 mm.

6. The method for manufacturing a polymer according to claim 1 ,
wherein a length of the reaction flow path is 3 to 100 m.

7. The method for manufacturing a polymer according to claim 1 ,
wherein the number of flow paths which are connected to a joining portion of the liquid A and the liquid B and through which the liquid A flows and the number of flow paths which are connected to the joining portion of the liquid A and the liquid B and through which the liquid B flows is 3 to 10 in total.

8. The method for manufacturing a polymer according to claim 1 ,
wherein at least one organic lithium compound or at least one organic magnesium compound is used as the anionic polymerization initiator.

9. The method for manufacturing a polymer according to claim 1 ,
wherein n-butyllithium is used as the anionic polymerization initiator.

10. The method for manufacturing a polymer according to claim 1 ,
wherein the liquid B contains an aromatic hydrocarbon.

11. A flow-type reaction system for manufacturing a polymer by an anionic polymerization reaction, the system comprising:
a first flow path through which an anionic polymerizable monomer flows;
a second flow path through which an anionic polymerization initiator flows;
a third flow path through which a polymerization terminator flows;
a first joining portion where the first flow path and the second flow path join together;
a reaction tube connected to downstream of the first joining portion;
a second joining portion where the reaction tube and the third flow path join together; and
a pipe line connected to downstream of the second joining portion,
wherein a static mixer is disposed in the reaction tube,
a polymer having a number-average molecular weight equal to or greater than 2,000 is introduced into an inlet port of the static mixer, and
a polymer having a number-average molecular weight of 5000 to 200,000 is obtained from the pipe line.

Assignees

• Fujifilm Corp

Inventors

• Wada Kenji
• Harada Kei

Classifications

• B01J19/243

  spirally, concentrically or zigzag wound · CPC title

• C08F4/484

  an alkali metal bound to a cyclic carbon · CPC title

• B01J19/245

  placed in series · CPC title

• C08F2/38

  Polymerisation using regulators, e.g. chain terminating agents {, e.g. telomerisation} · CPC title

• B01J19/0093 Primary

  Microreactors, e.g. miniaturised or microfabricated reactors (laboratory containers with capillary fluid transport in microfabricated channels or chambers B01L3/5027) · CPC title