Preparation method for gold nanoparticles based on functionalized ionic liquid

Patent metadata

Field	Value
Publication number	US-11241739-B2
Application number	US-201916438126-A
Country	US
Kind code	B2
Filing date	Jun 11, 2019
Priority date	Oct 15, 2018
Publication date	Feb 8, 2022
Grant date	Feb 8, 2022

Abstract

The present invention provides a preparation method for gold nanoparticles based on functionalized ionic liquid. The method comprises synthesizing a functionalized ionic liquid, 3-(12-bromo-dodecyl)-1-(3-pyrrole propyl)-imidazole bromide, as a stabilizer for synthesizing gold nanoparticles, adjusting the concentration of the ionic liquid and the dosage of the reducing agent, thereby successfully preparing the icosahedral gold nanoparticles, and characterizing the morphology thereof by TEM, XRD and SEM. In the present invention, the method employed for preparing the stabilizer is simple, non-toxic, harmless and pollution-free, moreover the preparation of gold nanoparticles by aqueous phase has the advantages of mild conditions, short reaction time, simple operation, green and pollution-free, and belongs to the environment-friendly preparation.

First claim

What is claimed is:

1. A preparation method for gold nanoparticles, characterized in comprising the following steps of:
S1, a step of seeded synthesis of gold nanoparticles comprising: putting 0.42 mL of 0.002 mol/L HAuCl4 solution into 0.951 mL of secondary distilled water and blending to obtain a first mixture, then adding 1.25 mL of 0.20-0.40 mol/L 3-(12-bromo-dodecyl)-1-(3-pyrrol-propyl)-imidazole bromide solution and 0.5 mL of new preparative 0.01 mol/L NaBH4 solution to the first mixture, thereby providing a second mixture and standing the second mixture at 27° C. for 2-4 hours, thereby obtaining gold nanoparticle seeds, and storing the gold nanoparticle seeds at 4° C. for later use;
S2, a step of synthesis of gold nanoparticles comprising: sequentially putting 2.6 mL of secondary distilled water, 1.67 mL of 2×10−3 mol/L HAuCl4 solution, 3.96 mL of 0.4-0.6 mol/L 3-(12-bromo-dodecyl)-1-(3-pyrrol-propyl) imidazole bromide solution and 54 μL of 0.1 mol/L ascorbic acid solution into a test tube and obtaining a third mixture, and stirring the third mixture vigorously for 2 minutes, lastly adding 100-150 μL of the gold nanoparticle seeds prepared in S1 to the third mixture and then stirring the third mixture for 20-40 seconds, and then standing the third mixture for 12-24 hours at 25-30° C., thereby obtaining a gold nanoparticles solution; and
S3, centrifuging the gold nanoparticles solution obtained in S2 to collect gold nanoparticle solids, then washing the gold nanoparticle solids with water and centrifuging again to collect the gold nanoparticle solids.

2. A preparation method for the gold nanoparticles of the claim 1 , characterized in that the concentration of the 3-(12-bromo-dodecyl)-1-(3-pyrrol-propyl)-imidazole bromide solution in S1 is 0.25 mol/L.

3. A preparation method for the gold nanoparticles of the claim 1 , characterized in that the concentration of the 3-(12-bromo-dodecyl)-1-(3-pyrrol-propyl)-imidazole bromide solution in S2 is 0.50 mol/L.

4. A preparation method for the gold nanoparticles of the claim 1 , characterized in that 120 μL of gold nanoparticle seeds prepared in S1 is added in S2.

5. A preparation method for the gold nanoparticles of the claim 1 , characterized in that the standing temperature in S2 is kept at 27° C. for 24 h to obtain the gold nanoparticles solution.

6. A preparation method for the gold nanoparticles of the claim 1 , wherein
the step of centrifuging the gold nanoparticles solution comprises centrifuging at a rate of 12000 r/min for 8-10 minutes to divide the gold nanoparticles solution into an upper liquid layer and a lower solid layer;
the upper liquid layer is removed and the lower solid layer comprises the gold nanoparticle solids collected from the centrifugation step; and
the step of washing comprises dispersing into water the gold nanoparticle solids collected from the centrifugation step; and
the step of centrifuging again comprises centrifuging the dispersion of water and gold nanoparticle solids obtained from the washing step to obtain the gold nanoparticle solids.

Assignees

• Univ Dongguan Technology

Inventors

• Zhang Min
• Dai Baosong

Classifications

• B22F1/054

  Nanosized particles · CPC title

• B22F9/24 Primary

  starting from liquid metal compounds, e.g. solutions · CPC title

• B22F2009/245

  Reduction reaction in an Ionic Liquid [IL] · CPC title

• B22F2304/054

  Particle size between 1 and 100 nm · CPC title

• B22F2202/17

  use of centrifugal or vortex forces · CPC title