Systems and methods for inertial sensing for VAD diagnostics and closed loop control

Patent metadata

Field	Value
Publication number	US-11241570-B2
Application number	US-201916511641-A
Country	US
Kind code	B2
Filing date	Jul 15, 2019
Priority date	Jul 17, 2018
Publication date	Feb 8, 2022
Grant date	Feb 8, 2022

Abstract

A blood circulation assist system includes a ventricular assist device (VAD) and a controller. The VAD is attachable to a heart of a patient to pump blood from a ventricle of the heart into a blood vessel of the patient. The VAD includes an impeller, a motor stator operable to rotate the impeller, and an accelerometer generating an accelerometer output indicative of accelerations of the VAD. The controller controls operation of the motor stator to control rotational speed of the impeller based on the accelerometer output.

First claim

What is claimed is:

1. A blood circulation assist system, comprising:
a ventricular assist device (VAD) comprising a housing defining a blood flow conduit, an impeller disposed within the blood flow conduit, a motor stator operable to rotate the impeller, and control electronics disposed within the housing, wherein the housing comprises an inlet cannula and is coupleable to a heart of a patient to receive blood into the inlet cannula from a ventricle of the heart and pump the blood to a blood vessel of the patient, wherein the control electronics are configured to control drive currents supplied to the motor stator to control magnetic levitation of the impeller and/or rotation of the impeller, and wherein the control electronics comprise an accelerometer generating an accelerometer output indicative of accelerations of the VAD; and
a controller operatively coupled with the control electronics, wherein the controller processes the accelerometer output and controls operation of the control electronics to control rotational speed of the impeller based on the accelerometer output.

2. The system of claim 1 , wherein the controller:
processes the accelerometer output to detect a cardiac cycle timing of the heart, the cardiac cycle timing including a heart rate of the heart and a time of occurrence for each of one or more cardiac cycle events for the heart; and
varies the rotational speed of the impeller in sync with the cardiac cycle timing.

3. The system of claim 2 , wherein the controller varies the rotational speed to during ventricular systole of the heart to increase a rate at which the VAD pumps blood from the ventricle to the blood vessel.

4. The system of claim 3 , wherein the controller is configured to accomplish one or more of:
process the accelerometer output to measure motion of a heart wall of the heart to which the housing is attached, and detect timing of ventricular systole of the heart based on the motion of the heart wall; and
process the accelerometer output to detect a time of occurrence of at least one heart sound, and detect timing of ventricular systole of the heart based on the time of occurrence of the at least one heart sound.

5. The system of claim 4 , wherein the at least one heart sound includes:
a sound of closure of the atrioventricular valves of the heart; and/or
a sound of closure of the semilunar valves of the heart.

6. The system of claim 2 , wherein the controller:
controls the control electronics to rotate the impeller at a constant speed throughout at least one complete cardiac cycle of the heart;
monitors drive current supplied to the motor stator to rotate the impeller at the constant speed; and
processes the monitored drive current to detect the cardiac cycle timing of the heart.

7. The system of claim 2 , wherein the controller varies the rotational speed of the impeller over a target cardiac cycle of the heart based on detected timing of one or more cardiac cycles of the heart that occur prior to the target cardiac cycle.

8. The system of claim 2 , wherein the controller varies the rotational speed of the impeller over a target cardiac cycle of the heart based on detected timing of the target cardiac cycle.

9. The system of claim 2 , wherein the controller:
processes the accelerometer output to measure an activity level of the patient; and
controls the rotational speed of the impeller based on the activity level.

10. The system of claim 9 , wherein the controller is configured to process the accelerometer output to measure a respiration rate for the patient and/or a diaphragm contraction for the patient, and base the activity level on the respiration rate and/or the diaphragm contraction.

11. The system of claim 1 , wherein the controller:
processes the accelerometer output to measure an activity level of the patient; and
controls the rotational speed of the impeller based on the activity level.

12. The system of claim 11 , wherein the controller is configured to process the accelerometer output to measure a respiration rate for the patient and/or a diaphragm contraction for the patient, and base the activity level on the respiration rate and/or the diaphragm contraction.

13. The system of claim 1 , wherein the controller is disposed within the housing.

14. The system of claim 1 , further comprising an external control unit operatively coupled with the VAD, wherein the controller is disposed within a housing of the external control unit.

15. The system of claim 1 , wherein the accelerometer output is indicative of accelerations of the VAD relative to three different axes.

16. A blood circulation assist system, comprising:
a ventricular assist device (VAD) comprising a housing defining a blood flow conduit, control electronics disposed within the housing, and a motor stator; wherein the housing comprises an inlet cannula and is coupleable to a heart of a patient to receive blood into the inlet cannula from a ventricle of the heart and pump the blood to a blood vessel of the patient, wherein the control electronics are operable to control currents supplied to the motor stator, and wherein the control electronics comprise an accelerometer generating an accelerometer output indicative of accelerations of the VAD; and
a controller that processes the accelerometer output to generate VAD monitoring data indicative of one or more operational parameters of the VAD.

17. The system of claim 16 , wherein:
the VAD comprises a magnetically levitated impeller and the motor stator is operable to rotate and magnetically levitate the impeller;
the control electronics are configured to control the currents supplied to the motor stator to control rotation and magnetic levitation of the impeller; and
the VAD monitoring data is indicative of vibrations of the impeller.

18. The system of claim 16 , wherein the VAD monitoring data is indicative of whether a suction event has occurred during an acquisition time period for the VAD monitoring data.

19. The system of claim 16 , further comprising a memory device in which the VAD monitoring data is stored, the VAD monitoring data stored in the memory device being accessible for subsequent display and/or processing.

Assignees

• Tc1 Llc

Inventors

• Hansen John Freddy
• Hill John Donald
• Andriola Peter
• Harjes Daniel I
• Lee Eric
• Valchera Gionata
• Mercier Nichole
• Salltakaj Urim

Classifications

• A61M60/232

  Centrifugal pumps · CPC title

• A61M60/178 Primary

  drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices · CPC title

• A61M60/816

  Sensors arranged on or in the housing, e.g. ultrasonic flow sensors · CPC title

• A61M60/538

  Regulation using real-time blood pump operational parameter data, e.g. motor current · CPC title

• A61M60/515

  Regulation using real-time patient data · CPC title