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US-2024000996-A1 · Jan 4, 2024 · US
Hydrogel composition and bioink composition including the same
US11241517B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11241517-B2 |
| Application number | US-201816165515-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 19, 2018 |
| Priority date | Oct 2, 2018 |
| Publication date | Feb 8, 2022 |
| Grant date | Feb 8, 2022 |
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Abstract
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Provided are a hydrogel composition with high viscoelasticity and a bioink composition including the hydrogel composition. The hydrogel composition according to an embodiment is composed of natural biocompatible substances and thus is not toxic, but has high viscosity, resulting in high mechanical stability or long persistence. Thus, the hydrogel composition may be usefully utilized as a bioink composition for bioprinting, a support in tissue engineering, or a soft tissue filler.
First claim
Opening claim text (preview).
What is claimed is: 1. A hydrogel bioink composition for bioprinting, comprising: 16% by weight to 18% by weight of collagen with respect to the total amount of the hydrogel bioink composition; and 0% by weight to 4% by weight of hyaluronic acid with respect to the total amount of the hydrogel bioink composition, wherein the hydrogel bioink composition does not further comprise a cross-linking agent, and wherein the hydrogel bioink composition has an elastic modulus in a range of 6,900 Pa to 9,500 Pa. 2. The hydrogel bioink composition of claim 1 , wherein the hydrogel bioink composition further comprises thrombin. 3. The hydrogel bioink composition of claim 1 , wherein the hydrogel bioink composition is used for skin regeneration. 4. The hydrogel bioink composition of claim 1 , wherein the hydrogel bioink composition is laden with cells. 5. The hydrogel bioink composition of claim 4 , wherein the cells are stem cells, sensory cells, brain cells, germ cells, epithelial cells, immune cells, cartilage cells, bone cells, or cancer cells. 6. A method of preparing a biocompatible structure, the method comprising: preparing a hydrogel bioink composition according to claim 1 ; and 3D-printing the composition to produce a support. 7. The method of claim 6 , wherein the method further comprises printing by layering cells on the support.
Assignees
Inventors
Classifications
Fibrin; Fibrinogen · CPC title
Hydrogels or hydrocolloids · CPC title
- A61L27/24Primary
Collagen · CPC title
Processes of additive manufacturing · CPC title
Materials specially adapted for additive manufacturing · CPC title
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- What does patent US11241517B2 cover?
- Provided are a hydrogel composition with high viscoelasticity and a bioink composition including the hydrogel composition. The hydrogel composition according to an embodiment is composed of natural biocompatible substances and thus is not toxic, but has high viscosity, resulting in high mechanical stability or long persistence. Thus, the hydrogel composition may be usefully utilized as a bioink…
- Who is the assignee on this patent?
- Korea Inst Sci & Tech
- What technology area does this patent fall under?
- Primary CPC classification A61L27/24. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Feb 08 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).