Medicament delivery devices

Patent metadata

Field	Value
Publication number	US-11235104-B2
Application number	US-201816483661-A
Country	US
Kind code	B2
Filing date	Feb 6, 2018
Priority date	Feb 6, 2017
Publication date	Feb 1, 2022
Grant date	Feb 1, 2022

Abstract

A medicament delivery device (100; 300; 400) comprises a chassis (124), a drive element (166) for driving a stopper (22) to expel the medicament through a cannula (144). A carrier (126) is arranged for movement with respect to the chassis (124). Insertion means (130, 202) biases the carrier (126) in an insertion direction. A control part (132) is biased for rotation with respect to the carrier (126). A locking element (176) prevents rotation of the control part (132) in an initial state. The locking element (176) is coupled to the drive element (166) such that the control part (132) is released for rotation when the drive element (166) reaches an activation position during a delivery stroke. Rotation of the control part (132) through a predetermined angle causes decoupling of the insertion means (130, 202) from the carrier (126) to allow movement of the carrier (126) in a retraction direction after the end of the delivery stroke.

First claim

The invention claimed is:

1. A medicament delivery device for delivery of medicament from a container into an injection site through a cannula, the device comprising:
a chassis;
a drive element for driving a stopper of the container in a delivery stroke to expel the medicament through the cannula;
a carrier arranged for movement with respect to the chassis in an insertion direction to advance the cannula from the device and in a retraction direction to withdraw the cannula after delivery of the medicament;
insertion means coupled to the carrier for biasing the carrier in the insertion direction;
a control part biased for rotation with respect to the carrier; and

a locking element cooperable with the control part for preventing rotation of the control part with respect to the carrier in an initial state of the device,
wherein the locking element is coupled to the drive element such that the control part is released for rotation when the drive element reaches an activation position during the delivery stroke,
wherein the rotation of the control part through a predetermined angle with respect to the carrier causes decoupling of the insertion means from the carrier to allow movement of the carrier in the retraction direction after the end of the delivery stroke,
wherein the control part is coupled to the carrier for joint axial movement at least in the insertion direction,
wherein the insertion means is coupled to the carrier by way of the control part,
wherein the insertion means comprises a coupling member for engagement with the control part and an insertion spring for biasing the coupling member in the insertion direction, and
wherein the control part comprises an inclined formation for engagement with the coupling member, such that the coupling member biases the control part for the rotation with respect to the carrier.

2. The device according to claim 1 , comprising retarding means for controlling speed of the rotation of the control part.

3. The device according to claim 2 , wherein the retarding means comprises a rotational damper.

4. The device according to claim 3 , wherein the rotational damper comprises a chamber for receiving a viscous substance and at least one vane arranged for movement through the viscous substance upon the rotation of the control part with respect to the carrier.

5. The device according to claim 4 , wherein the chamber is defined at least in part by the carrier and at least in part by the control part.

6. The device according to claim 3 , wherein the rotational damper comprises a chamber for receiving a viscous substance and at least one projection arranged to constrict movement of the viscous substance through the chamber upon the rotation of the control part with respect to the carrier.

7. The device according to claim 1 , wherein the locking element is engageable with the control part to prevent the rotation of the control part with respect to the carrier, and wherein the locking element disengages from the control part when the drive element reaches the activation position.

8. The device according to claim 7 , wherein the locking element is engageable with an opening in the control part, and wherein the locking element withdraws from the opening when the drive element reaches the activation position.

9. The device according to claim 1 , wherein the locking element is flexible to adopt a non-linear storage configuration in the initial state of the device.

10. The device according to claim 1 , wherein the locking element comprises an elongate extension of the drive element.

11. The device according to claim 1 , wherein the locking element is an elongate member slidably coupled to the drive element.

12. The device according to claim 1 , wherein the drive element reaches the activation position before the end of the delivery stroke.

13. The device according to claim 1 , further comprising a retainer for holding the drive element in a starting position with respect to the carrier and for releasing the drive element to start the delivery stroke.

14. The device according to claim 13 , wherein the retainer is arranged to release the drive element after movement of the carrier in the insertion direction.

15. The device according to claim 14 , wherein the retainer comprises a retaining member for engagement with the locking element to hold the drive element in the starting position, and wherein the movement of the carrier in the insertion direction with respect to the chassis causes disengagement of the retaining member from the locking element.

16. The device according to claim 15 , wherein the locking element comprises an aperture for receiving the retaining member.

17. The device according to claim 15 , wherein the chassis comprises the retaining member.

18. The device according to claim 15 , wherein the retainer further comprises a latching arm connected to the drive element and for engagement between the carrier and the retaining member in the starting position.

19. The device according to claim 1 , wherein the control part is rotatable around a longitudinal axis of the carrier.

20. The device according to claim 1 , wherein the coupling member disengages from the control part upon the rotation of the control part through the predetermined angle.

21. The device according to claim 1 , comprising a latch for holding the carrier in an initial position with respect to the chassis, and a trigger that is operable to release the latch to allow movement of the carrier in the insertion direction.

22. The device according to claim 21 , comprising a casing for receiving the chassis, wherein the casing is moveable in the insertion direction with respect to the chassis to operate the trigger to release the latch.

23. The device according to claim 22 , further comprising a chassis locking mechanism between the casing and the chassis for lockably connecting the casing to the chassis once the casing has moved in the insertion direction.

24. The device according to claim 1 , further comprising:
a removable cap for closing an end of a casing and for preventing movement of the casing with respect to the chassis while the cap is attached to the casing; and
a latching mechanism between the casing and the chassis for preventing the movement of the casing with respect to the chassis, wherein the removable cap prevents disengagement of the latching mechanism while the cap is attached to the casing.

25. The device according to claim 1 ,
wherein the carrier comprises a cannula holder for retaining the cannula;
wherein the container comprises a cartridge having a sealing element for closing an outlet of the cartridge; and
wherein the device comprises a sealing element release member that is cooperable with the sealing element to open the outlet and to establish a flow path from the cartridge to the cannula.

26. A method of treating a patient having a condition susceptible to treatment with the medicament, the method comprising:
dispensing an effective amount of the medicament to the patient utilizing the delivery device according to claim 1 ;
wherein the medicament is disposed in the container and is dispensed into the injection site on the patient through the cannula.

27. A medicament delivery device for delivery of medicament from a container into an injection site through a cannula, the device comprising:
a chassis;
a drive element biased for dr

Assignees

• Owen Mumford Ltd

Inventors

• Cowe Toby
• Evans Timothy

Classifications

• A61M5/3202

  Devices for protection of the needle before use, e.g. caps (A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001) · CPC title

• A61M2005/2073

  preventing premature release, e.g. by making use of a safety lock · CPC title

• A61M5/3234

  Fully automatic needle retraction, i.e. in which triggering of the needle does not require a deliberate action by the user · CPC title

• A61M5/2033 Primary

  Spring-loaded one-shot injectors with or without automatic needle insertion (multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287) · CPC title

• A61M2005/2086

  having piston damping means, e.g. axially or rotationally acting retarders · CPC title