Ultrasound localization system with advanced biopsy site markers

Patent metadata

Field	Value
Publication number	US-11234772-B2
Application number	US-201816771379-A
Country	US
Kind code	B2
Filing date	Dec 11, 2018
Priority date	Dec 11, 2017
Publication date	Feb 1, 2022
Grant date	Feb 1, 2022

Abstract

Disclosed biopsy markers are adapted to serve as localization markers during a surgical procedure. Adaptation includes incorporation of materials detectable under ultrasound during surgery, as well as features for co-registration with image guidance or other real-time imaging technologies during surgery. Such biopsy markers, when used as localization markers, improve patient comfort and reduce challenges in surgical coordination and surgery time. Additional disclosed biopsy markers are adapted to serve as monitoring and/or detection apparatuses. Localization of an implanted marker may be done with ultrasound technology. Ultrasound image data is analyzed to identify the implanted marker. A distance to the marker or a lesion may be determined and displayed. The determined distance may be a distance between the ultrasound probe and the marker or lesion, a distance between the marker or lesion and an incision instrument, and/or a distance between the ultrasound probe and the incision instrument.

First claim

What is claimed is:

1. A method for localization of an implanted marker with ultrasound technology, the method comprising:
emitting a first array of ultrasonic sound waves from an ultrasonic transducer of an ultrasound probe in a first position;
detecting first reflected ultrasonic sound waves by the ultrasonic transducer, wherein the first reflected ultrasonic sound waves include at least a portion of the first array of ultrasonic sound waves after being reflected from a marker implanted within an interior of a patient;
generating first image data from the first reflected ultrasonic sound waves;
analyzing, by a processor, the generated first image data to identify the marker within the interior of the patient;
emitting a second array of ultrasonic sound waves from the ultrasonic transducer of the ultrasound probe in a second position;
detecting second reflected ultrasonic sound waves by the ultrasonic transducer, wherein the second reflected ultrasonic sound waves include at least a portion of the second array of ultrasonic sound waves after being reflected from within the interior of the patient;
generating second image data from the second reflected ultrasonic sound waves;
analyzing, by the processor, the generated second image data to determine the marker is not present within the generated second image data;
generating a navigation indicator, wherein the navigation indicator indicates a direction of the marker relative to the second position of the ultrasound probe; and
displaying the navigation indicator on a display concurrently with an ultrasound image generated from the second image data.

2. The method of claim 1 , further comprising:
generating a first image from the first image data; and
displaying the first image on the display.

3. The method of claim 2 , further comprising:
based at least in part on the identification of the marker in the generated first image data, determining a distance to the marker within the interior of the patient; and
displaying on the display, concurrently with the display of the first image, the determined distance to the marker.

4. The method of claim 3 , wherein the determined distance to the marker is one of: a distance from a portion of the ultrasound probe to the marker, a distance from a portion of a scalpel to the marker, or a distance from a portion of a cautery tool to the marker.

5. The method of claim 1 , wherein the navigation indicator is an arrow pointing in the direction of the marker relative to the second position of the ultrasound probe.

6. A method for localization of an implanted marker with ultrasound technology, the method comprising:
emitting a first array of ultrasonic sound waves from an ultrasonic transducer of an ultrasound probe in a first position;
detecting first reflected ultrasonic sound waves by the ultrasonic transducer, wherein the first reflected ultrasonic sound waves include at least a portion of the first array of ultrasonic sound waves after being reflected from a marker implanted within an interior of a patient;
generating first image data from the first reflected ultrasonic sound waves;
analyzing, by a processor, the generated first image data to identify the marker within the interior of the patient;
based at least in part on the identification of the marker in the generated first image data, determining a distance to the marker within the interior of the patient;
displaying on a display, concurrently with display of a first image generated from the first image data, the determined distance to the marker;
emitting a second array of ultrasonic sound waves from the ultrasonic transducer of the ultrasound probe in a second position;
detecting second reflected ultrasonic sound waves by the ultrasonic transducer, wherein the second reflected ultrasonic sound waves include at least a portion of the second array of ultrasonic sound waves after being reflected from within the interior of the patient;
generating second image data from the second reflected ultrasonic sound waves;
analyzing, by the processor, the generated second image data to determine the marker is not present within the generated second image data;
generating a navigation indicator, wherein the navigation indicator indicates a direction of the marker relative to the second position of the ultrasound probe; and
displaying the navigation indicator on the display concurrently with an ultrasound image generated from the second image data, wherein the navigation indicator is an arrow pointing in the direction of the marker relative to the second position of the ultrasound probe.

7. The method of claim 6 , wherein the determined distance to the marker is one of: a distance from a portion of the ultrasound probe to the marker, a distance from a portion of a scalpel to the marker, or a distance from a portion of a cautery tool to the marker.

Assignees

• Hologic Inc

Inventors

• Laviola John
• St Pierre Shawn
• Stellmach Brian
• Fontaine Lori
• Stand Iii Joseph A
• Alvarez Estefania
• Grantz Stephen
• Lyman Michelle Dawn
• Butler Shannon Marie
• Mathis Yuliya

Classifications

• A61B8/0825

  for diagnosis of the breast, e.g. mammography · CPC title

• A61B2017/00867

  shape memory effect · CPC title

• A61B34/25

  User interfaces for surgical systems · CPC title

• A61B2090/3912

  Body cavities · CPC title

• A61B5/4842

  Monitoring progression or stage of a disease · CPC title