Vaccine composition against Chlamydiaceae infections

US11229691B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-11229691-B2
Application numberUS-202016884649-A
CountryUS
Kind codeB2
Filing dateMay 27, 2020
Priority dateJul 28, 2015
Publication dateJan 25, 2022
Grant dateJan 25, 2022

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  1. Title

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  2. Abstract

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  5. First independent claim

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Abstract

Official abstract text for this publication.

The invention relates to vaccine compositions for treating and/or preventing infections by a bacterium of the Chlamydiaceae family, said compositions comprising bacteria of the Chlamydiaceae family, which have been previously treated by at least one peptidoglycan inhibitor, or extracts of said treated bacteria.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method of treating infections caused by Chlamydia bacteria selected in the group consisting of Chlamydia muridarum, Chlamydia pneumoniae, Chlamydia psitacci, Chlamydia abortus, Chlamydia felis, Chlamydia caviae, Chlamydia pecorum, Chlamydia suis and Chlamydia trachomatis , comprising: administering to a subject in need thereof a composition comprising a therapeutically effective amount of an inactivated BL form of Chlamydia bacteria selected from the group consisting of Chlamydia muridarum, Chlamydia pneumoniae, Chlamydia psitacci, Chlamydia abortus, Chlamydia felis, Chlamydia caviae, Chlamydia pecorum, Chlamydia suis and Chlamydia trachomatis, wherein the inactivated BL form of Chlamydia bacteria has been previously inactivated by treating with a β-lactam, wherein the β-lactam is selected from the group consisting of amoxicillin, benzylpenicillin, phenoxymethylpenicillin, cloxacillin, cefadroxil, cefixime, imipenem, mecillinam, clavulanic acid, tazobactam, sulbactam, and the combination of cefixime and imipenem. 2. The method of claim 1 , wherein said β-lactam is penicillin G. 3. The method of claim 1 , wherein Chlamydia bacteria is Chlamydia trachomatis or Chlamydia muridarum. 4. The method of claim 1 , wherein a pathology caused by the infection with Chlamydia bacteria is an ocular pathology, a genital pathology, a respiratory pathology, a cardiovascular dysfunction, a circulatory dysfunction, a joint disease, or an inflammatory disease. 5. The method of claim 4 , wherein said genital pathology is selected from the group consisting of venereal lymphogranuloma, urethritis, orchiepididymitis, cervicovaginitis, cervicitis, endocervicitis, endometritis, perihepatitis and salpingitis.

Assignees

Inventors

Classifications

  • inactivated (killed) · CPC title

  • Infectious diseases, e.g. generalised sepsis · CPC title

  • A61K39/118Primary

    Chlamydiaceae, e.g. Chlamydia trachomatis or Chlamydia psittaci · CPC title

  • Antibacterial agents · CPC title

  • Chlamydia · CPC title

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Frequently asked questions

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What does patent US11229691B2 cover?
The invention relates to vaccine compositions for treating and/or preventing infections by a bacterium of the Chlamydiaceae family, said compositions comprising bacteria of the Chlamydiaceae family, which have been previously treated by at least one peptidoglycan inhibitor, or extracts of said treated bacteria.
Who is the assignee on this patent?
Centre Nat Rech Scient, Univ Paris Diderot Paris 7, Inst Nat Sante Rech Med
What technology area does this patent fall under?
Primary CPC classification A61K39/118. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jan 25 2022 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).