Chlamydia antigens
US-9675683-B2 · Jun 13, 2017 · US
US11229691B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-11229691-B2 |
| Application number | US-202016884649-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 27, 2020 |
| Priority date | Jul 28, 2015 |
| Publication date | Jan 25, 2022 |
| Grant date | Jan 25, 2022 |
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The invention relates to vaccine compositions for treating and/or preventing infections by a bacterium of the Chlamydiaceae family, said compositions comprising bacteria of the Chlamydiaceae family, which have been previously treated by at least one peptidoglycan inhibitor, or extracts of said treated bacteria.
Opening claim text (preview).
The invention claimed is: 1. A method of treating infections caused by Chlamydia bacteria selected in the group consisting of Chlamydia muridarum, Chlamydia pneumoniae, Chlamydia psitacci, Chlamydia abortus, Chlamydia felis, Chlamydia caviae, Chlamydia pecorum, Chlamydia suis and Chlamydia trachomatis , comprising: administering to a subject in need thereof a composition comprising a therapeutically effective amount of an inactivated BL form of Chlamydia bacteria selected from the group consisting of Chlamydia muridarum, Chlamydia pneumoniae, Chlamydia psitacci, Chlamydia abortus, Chlamydia felis, Chlamydia caviae, Chlamydia pecorum, Chlamydia suis and Chlamydia trachomatis, wherein the inactivated BL form of Chlamydia bacteria has been previously inactivated by treating with a β-lactam, wherein the β-lactam is selected from the group consisting of amoxicillin, benzylpenicillin, phenoxymethylpenicillin, cloxacillin, cefadroxil, cefixime, imipenem, mecillinam, clavulanic acid, tazobactam, sulbactam, and the combination of cefixime and imipenem. 2. The method of claim 1 , wherein said β-lactam is penicillin G. 3. The method of claim 1 , wherein Chlamydia bacteria is Chlamydia trachomatis or Chlamydia muridarum. 4. The method of claim 1 , wherein a pathology caused by the infection with Chlamydia bacteria is an ocular pathology, a genital pathology, a respiratory pathology, a cardiovascular dysfunction, a circulatory dysfunction, a joint disease, or an inflammatory disease. 5. The method of claim 4 , wherein said genital pathology is selected from the group consisting of venereal lymphogranuloma, urethritis, orchiepididymitis, cervicovaginitis, cervicitis, endocervicitis, endometritis, perihepatitis and salpingitis.
inactivated (killed) · CPC title
Infectious diseases, e.g. generalised sepsis · CPC title
Chlamydiaceae, e.g. Chlamydia trachomatis or Chlamydia psittaci · CPC title
Antibacterial agents · CPC title
Chlamydia · CPC title
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