Ureteral stents and methods of using the same

Patent metadata

Field	Value
Publication number	US-11224502-B2
Application number	US-201716067928-A
Country	US
Kind code	B2
Filing date	Jan 5, 2017
Priority date	Jan 8, 2016
Publication date	Jan 18, 2022
Grant date	Jan 18, 2022

Abstract

Embodiments disclosed herein relate to ureteral stents having an elongated stent body and one or more deformable bladders secured thereto, and methods of using the same.

First claim

What is claimed is:

1. A ureteral stent, comprising:
an elongated stent body including:
a proximal end region including a first retaining structure, the proximal end region configured for positioning in a kidney;
a distal end region configured for positioning in a bladder and spaced longitudinally from the proximal end region;
an outer surface; and
an inner surface defining a lumen extending between the proximal end region and the distal end region of the elongated stent body; and

a deformable bladder secured to and surrounding at least a portion of the distal end region of the elongated stent body, the deformable bladder including:
a resiliently deformable imperforate envelope; and
an inert fluid imperforately sealed within the resiliently deformable imperforate envelope.

2. The ureteral stent of claim 1 , wherein the resiliently deformable envelope is formed from a material having a modulus of elasticity and dimensions effective to allow the deformable bladder to elongate along a portion of the outer surface of the elongated stent body and reduce the at least one cross-sectional dimension responsive to an external pressure applied thereto.

3. The ureteral stent of claim 1 , wherein:
the elongated stent body includes one or more of a perforated portion, a discontinuity, a portion having a thinner construction than adjacent portions of the elongated stent body, or a portion made with a different and more collapsible material than surrounding portions of the elongated stent body; and
the perforated portion, the discontinuity, the portion having the thinner construction, or the portion made with the different and more collapsible material is configured to collapse and substantially close the lumen responsive to external pressure from the bladder during urination.

4. The ureteral stent of claim 1 , wherein the resiliently deformable imperforate envelope includes an elastomer having one or more of silicone rubber, natural rubber, natural polyisoprene, polyurethane, synthetic polyisoprene nylon, or nitrile.

5. The ureteral stent of claim 1 , wherein the inert fluid includes one or more of mineral oil, cold-pressed vegetable oil, coconut oil, almond oil, olive oil, or a seed oil.

6. The ureteral stent of claim 1 , wherein the resiliently deformable imperforate envelope, including the inert fluid therein, is sized and configured to deform and fit inside of a delivery sheath suitable for insertion into a ureter of a subject.

7. The ureteral stent of claim 6 , further comprising the delivery sheath, the delivery sheath configured to fit over a length of the ureteral stent and cause the resiliently deformable imperforate envelope to at least partially deform and fit therein.

8. The ureteral stent of claim 1 , wherein the deformable bladder has a substantially teardrop deployed shape.

9. The ureteral stent of claim 1 , wherein the resiliently deformable imperforate envelope has a first portion and a second portion, the first portion having a greater wall thickness than the second portion.

10. The ureteral stent of claim 9 , wherein the elongated stent body includes a collapsible portion, the collapsible portion including one or more of a perforated portion, a discontinuity, a portion having a thinner construction than adjacent portions of the elongated stent body, or a portion made with a different, a more collapsible material than sidewall material in surrounding portions of the elongated stent body;
wherein each of the perforated portion, the discontinuity, the portion having a thinner construction, or the portion made with the different, more collapsible material is configured to collapse and substantially close the lumen of the elongated stent body responsive to external pressure from the bladder during urination; and
wherein the second portion of the resiliently deformable envelope is positioned proximate to the collapsible portion of the elongated stent body when the resiliently deformable envelope is in a deployed configuration.

11. The ureteral stent of claim 1 , wherein the first retaining structure includes an additional deformable bladder, the additional deformable bladder including:
an additional resiliently deformable envelope that is imperforately sealed; and
an additional inert fluid disposed in the additional resiliently deformable envelope;
wherein the additional resiliently deformable envelope is configured to allow the additional deformable bladder to elongate along a portion of the outer surface of the elongated stent body and reduce at least one cross-sectional dimension of the additional resiliently deformable envelope responsive to external pressure applied thereto.

12. The ureteral stent of claim 11 , wherein the additional resiliently deformable envelope includes an elastomer having one or more of silicone rubber, natural rubber, natural polyisoprene, synthetic polyisoprene polyurethane, nylon, or nitrile.

13. The ureteral stent of claim 11 , wherein the additional inert fluid includes one or more of mineral oil, cold-pressed vegetable oil, coconut oil, almond oil, olive oil, or a seed oil.

14. The ureteral stent of claim 11 , wherein the additional deformable bladder is configured identically to the deformable bladder.

15. The ureteral stent of claim 1 , wherein the elongated stent body is coated with at least one material selected from gold, palladium, and silver.

16. The urethral stent of claim 1 , wherein the elongated stent body and the deformable bladder have no filling port or valve.

Assignees

• Bard Inc C R

Inventors

• Goldman David Matthew
• Curry Peter
• Urban Joseph Anthony
• Wiste Jeremy M

Classifications

• A61F2002/047

  Urethrae · CPC title

• A61F2/04 Primary

  Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts (A61F2/18, A61F2/20 take precedence; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95) · CPC title

• A61M5/00

  Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests ({vaccination appliances for veterinary use A61D1/025} ; tube connectors, tube couplings, valves or branch units specially adapted for medical use A61M39/00; containers specially adapted for medical or pharmaceutical purposes A61J1/00; {combinations of vial and syringe for mixing or transferring their contents A61J1/20; holders for containers for collecting, storing or administering blood or medical fluids A61J1/16}) · CPC title

• A61M27/008

  pre-shaped, for use in the urethral or ureteral tract · CPC title